Caffeine Citrate | List of Frontiers open access articles

Original Research

Published on 13 May 2026

Clinical and biological impact of caffeine therapy in premature infants with apnea of prematurity: a prospective observational study

in Obstetrics and Gynecology

Adela-Valeria Neamțu
Ovidiu Mircea Zlatian
Andrei Theodor Bălășoiu
Costel-Valentin Manda
Carla-Maria Bărbulescu-Mateescu
Ana-Maria Pătrașcu
Ramona Cioboată
Liliana Stanca
Olivia Garofița Mateescu
Ștefan Pătrașcu

Frontiers in Medicine

doi 10.3389/fmed.2026.1808401

275 views

Review

Published on 18 Dec 2025

The utility of caffeine citrate as a neuroprotectant in the early life of premature newborns: a literature review of the effects on neurodevelopmental outcomes

in Neonatology

Lauren Phung
Kaithlyn Duong
Rawad Obeid

Frontiers in Pediatrics

doi 10.3389/fped.2025.1682903

1,977 views
1 citation

Clinical Trial

Published on 11 Mar 2020

Caffeine Citrate for Apnea of Prematurity: A Prospective, Open-Label, Single-Arm Study in Chinese Neonates

in Neonatology

Lizhong Du
Xiaomei Tong
Chao Chen
Xirong Gao
Alessandra Gagnatelli
Jingyang Li
Debora Santoro
Sara Nicolardi
Laura Fabbri
The Peyona Chinese Study Group

Frontiers in Pediatrics

doi 10.3389/fped.2020.00076

10,923 views
6 citations

Original Research

Published on 22 Jul 2024

Association between PER and CRY gene polymorphisms and the response to caffeine citrate treatment in infants with apnea of prematurity

in Neonatology

Jiang-Biao Xie
Wei Zhuang
Yao Zhu
Zhi Zheng
Yan-Ru Huang
Si-Min Ma
Xin-Zhu Lin

Frontiers in Pediatrics

doi 10.3389/fped.2024.1414185

2,257 views
1 citation

Original Research

Published on 25 Jan 2022

Caffeine Therapy for Apnea of Prematurity: Role of the Circadian CLOCK Gene Polymorphism

in Obstetric and Pediatric Pharmacology

Hong-Li Guo
Jia-Yi Long
Ya-Hui Hu
Yun Liu
Xin He
Ling Li
Ying Xia
Xuan-Sheng Ding
Feng Chen
Jing Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.724145

6,599 views
17 citations

Original Research

Published on 23 Jun 2025

Impact of cessation of caffeine citrate therapy on intermittent hypoxemia patterns among preterm infants born before 34 weeks

in Neonatology

Peter Kipkurui Mashep
Roseline Ochieng
Jesse Coleman
Mary Waiyego
Amy Sarah Ginsburg
Dorothy Chomba
Morris Ogero Ondieki
Grace Irimu
William M. Macharia
J. Mark Ansermino

Frontiers in Pediatrics

doi 10.3389/fped.2025.1463484

2,636 views
1 citation

Review

Published on 26 Jul 2021

Caffeine for the Pharmacological Treatment of Apnea of Prematurity in the NICU: Dose Selection Conundrum, Therapeutic Drug Monitoring and Genetic Factors

in Obstetric and Pediatric Pharmacology

Jia-Yi Long
Hong-Li Guo
Xin He
Ya-Hui Hu
Ying Xia
Rui Cheng
Xuan-Sheng Ding
Feng Chen
Jing Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.681842

27,366 views
36 citations

Original Research

Published on 27 Feb 2025

Caffeine use in preterm neonates: national insights into Turkish NICU practices

in Neonatology

Sezin Unal
Serdar Beken
Deniz Anuk Ince
Ozden Turan
Ayse Korkmaz Toygar
Ayse Ecevit
Abdullah Baris Akcan
Mustafa Ali Akın
Selma Aktas
Nukhet Aladag Ciftdemir

Frontiers in Pediatrics

doi 10.3389/fped.2025.1492716

8,292 views
1 citation

Articles

Clinical and biological impact of caffeine therapy in premature infants with apnea of prematurity: a prospective observational study

The utility of caffeine citrate as a neuroprotectant in the early life of premature newborns: a literature review of the effects on neurodevelopmental outcomes

Caffeine Citrate for Apnea of Prematurity: A Prospective, Open-Label, Single-Arm Study in Chinese Neonates

Association between PER and CRY gene polymorphisms and the response to caffeine citrate treatment in infants with apnea of prematurity

Caffeine Therapy for Apnea of Prematurity: Role of the Circadian CLOCK Gene Polymorphism

Impact of cessation of caffeine citrate therapy on intermittent hypoxemia patterns among preterm infants born before 34 weeks

Caffeine for the Pharmacological Treatment of Apnea of Prematurity in the NICU: Dose Selection Conundrum, Therapeutic Drug Monitoring and Genetic Factors

Caffeine use in preterm neonates: national insights into Turkish NICU practices