Checkpoint Inhibitor Therapy | List of Frontiers open access articles

Original Research

Published on 17 Feb 2026

Comparative analysis of oncologic outcomes: kidney-sparing surgery versus radical nephroureterectomy for localized high-risk upper tract urothelial carcinoma

in Genitourinary Oncology

Hongyu Zhang
Qi Tan
Yutao He
Tong Zhang
Yunfeng He

Frontiers in Oncology

doi 10.3389/fonc.2026.1753148

101 views

Original Research

Published on 17 Feb 2026

Application of a small molecule calcium influx inducer as a vaccine adjuvant: enhancing Th2-biased immune responses

in Vaccines and Molecular Therapeutics

Yumi Yokoyama
Yukiya Sako
Shiyin Yao
Fernando Gil
Renna Cozza
Jasmine Jin
Ian Mclaughlin
Paola Anguiano Quiroz
Tyler Brown
Nikunj M. Shukla

Frontiers in Immunology

doi 10.3389/fimmu.2026.1704416

163 views

Original Research

Published on 17 Feb 2026

Genetic diversity and molecular characterization of avian paramyxoviruses from wild birds in South Korea between 2020 and 2024

in Virology

Eun-Jee Na
Su-Beom Chae
Young-Sik Kim
Jun-Soo Park
Serin Sim
Seung-Chai Kim
Hwan-Ju Kim
Chang-Gi Jeong
Jae-Ku Oem

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1732075

233 views

Case Report

Published on 17 Feb 2026

Case Report: Neo-homozygous nonsense mutation in NLRP5 associated with early embryonic arrest in two sisters from a Chinese family

in Assisted Reproduction

Qin Xu
Yumei Deng
Jingjing Huo
Yuanlong Yan
Yangjia Zhang
Yaxian Ma
Li Zhuan

Frontiers in Reproductive Health

doi 10.3389/frph.2026.1767934

130 views

Original Research

Published on 17 Feb 2026

Seeing through the virtual reality: the effects of learning environment and task difficulty on difficulty perception, learning outcomes and mental models

in Educational Psychology

Meixian Shan
Suying Du
Chenyu Shangguan
Mei Li

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1772894

113 views

Original Research

Published on 17 Feb 2026

Analysis of risk factors for early recurrence after radiofrequency ablation in patients with atrial fibrillation and construction of a nomogram predictive model

in Cardiac Rhythmology

Jia-Nan Wang
Hui-Lan Liu
Hui-Hong Hong
Ting-Pei Zhuang
Bing Wu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1659637

145 views

Brief Research Report

Published on 17 Feb 2026

Synergy between explicit teaching, ICT integration, and the TaRL approach: structural modeling of learning gains

in Digital Education

Mounia Machkour
Hiba Gharbaoui
Latifa Lamalif
Sophia Faris
Khalifa Mansouri

Frontiers in Education

doi 10.3389/feduc.2026.1742242

170 views

Original Research

Published on 17 Feb 2026

Glutamate transmission in the prelimbic cortex and nucleus accumbens shell is involved in ethanol reinforcement and drinking in rats

in Motivation and Reward

Xiaoying Tan
William J. McBride
Zheng-Ming Ding

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2026.1745128

236 views

Original Research

Published on 17 Feb 2026

ctDNA guided management of POLE mutant GI malignancies promotes exceptional responses and prolonged survival to immunotherapy

in Cancer Immunity and Immunotherapy

Umair Mahmood
Chetan Bhan
Charles Imber
Jamie Murphy
Krish Menon
Tara D. Barwick
Zahir Amin
Khurum Khan

Frontiers in Immunology

doi 10.3389/fimmu.2026.1738295

Correction

Published on 17 Feb 2026

Correction: Fatal adverse events associated with programmed cell death ligand 1 inhibitors: a systematic review and meta-analysis

in Drugs Outcomes Research and Policies

Xuewen Wang
Shijie Wu
Yaying Chen
Erqian Shao
Tingting Zhuang
Linbin Lu
Xiong Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1782058

Mini Review

Published on 17 Feb 2026

Modulation of CCR2/CCL2 molecular axis in the expansion and rupture of abdominal aortic aneurysms

in Atherosclerosis and Vascular Medicine

Ryan Wahidi
Santiago Elizondo-Benedetto
Ryan Catlett
Bera Koklu
Mohamed A. Zayed

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1772497

222 views

Original Research

Published on 17 Feb 2026

Evidence for modulation of the fecal microbiota profile by diet in lactating buffalo

in Animal Nutrition and Metabolism

Chiara Evangelista
Daniele Pietrucci
Marco Milanesi
Federica Gabbianelli
Loredana Basiricò
Sebastiana Failla
Giovanni Chillemi
Umberto Bernabucci

Frontiers in Veterinary Science

doi 10.3389/fvets.2026.1739986

251 views

Original Research

Published on 17 Feb 2026

Multi-site cardiac rhythm monitoring via multi-channel SCG system and exercise-induced physiological analysis

in Cardiac Electrophysiology

Miaoyang Hu
Huansheng Yi
Wenjun Yan
Wei Ren
Jianqi Wang
Fugui Qi

Frontiers in Physiology

doi 10.3389/fphys.2026.1727160

193 views

Review

Published on 17 Feb 2026

The chitinolytic enzymes from the entomopathogenic fungus Metarhizium anisopliae: GH family distribution, domain architecture, and protein regulation

in Fungi-Animal Interactions

Qusai Al Abdallah
Kholoud M. Alananbeh
Nehaya Al-Karablieh
Salah-Eddin Araj

Frontiers in Fungal Biology

doi 10.3389/ffunb.2026.1732437

215 views

Original Research

Published on 17 Feb 2026

“A supplement, not a substitute” - relational experiences of neurodiverse graduate students with an AI Virtual Mentor

in STEM Education

Connie Mosher Syharat
Arash Zaghi

Frontiers in Education

doi 10.3389/feduc.2026.1769327

161 views

Original Research

Published on 17 Feb 2026

Symbiotic N2-fixation, carbon accumulation and water-use efficiency of 63 common bean (Phaseolus vulgaris L.) genotypes grown under field conditions at Malkerns, Eswatini using the 15N and 13C natural abundance technique

in Plant-Soil Interactions

Rotondwa Pascalia Gunununu
Titus Yeliku-ang Ngmenzuma
Felix Dapare Dakora
Mustapha Mohammed

Frontiers in Agronomy

doi 10.3389/fagro.2025.1713315

377 views

Articles

Comparative analysis of oncologic outcomes: kidney-sparing surgery versus radical nephroureterectomy for localized high-risk upper tract urothelial carcinoma

Application of a small molecule calcium influx inducer as a vaccine adjuvant: enhancing Th2-biased immune responses

Genetic diversity and molecular characterization of avian paramyxoviruses from wild birds in South Korea between 2020 and 2024

Case Report: Neo-homozygous nonsense mutation in NLRP5 associated with early embryonic arrest in two sisters from a Chinese family

Seeing through the virtual reality: the effects of learning environment and task difficulty on difficulty perception, learning outcomes and mental models

Analysis of risk factors for early recurrence after radiofrequency ablation in patients with atrial fibrillation and construction of a nomogram predictive model

Synergy between explicit teaching, ICT integration, and the TaRL approach: structural modeling of learning gains

Glutamate transmission in the prelimbic cortex and nucleus accumbens shell is involved in ethanol reinforcement and drinking in rats

ctDNA guided management of POLE mutant GI malignancies promotes exceptional responses and prolonged survival to immunotherapy

Correction: Fatal adverse events associated with programmed cell death ligand 1 inhibitors: a systematic review and meta-analysis

Modulation of CCR2/CCL2 molecular axis in the expansion and rupture of abdominal aortic aneurysms

Evidence for modulation of the fecal microbiota profile by diet in lactating buffalo

Multi-site cardiac rhythm monitoring via multi-channel SCG system and exercise-induced physiological analysis

The chitinolytic enzymes from the entomopathogenic fungus Metarhizium anisopliae: GH family distribution, domain architecture, and protein regulation

“A supplement, not a substitute” - relational experiences of neurodiverse graduate students with an AI Virtual Mentor

Symbiotic N2-fixation, carbon accumulation and water-use efficiency of 63 common bean (Phaseolus vulgaris L.) genotypes grown under field conditions at Malkerns, Eswatini using the 15N and 13C natural abundance technique