Checkpoint Pathways | List of Frontiers open access articles

Review

Published on 15 Dec 2022

In or out of control: Modulating regulatory T cell homeostasis and function with immune checkpoint pathways

in Immunological Tolerance and Regulation

Maha Abdeladhim
Jodi L. Karnell
Sadiye Amcaoglu Rieder

Frontiers in Immunology

doi 10.3389/fimmu.2022.1033705

8,235 views
30 citations

Review

Published on 13 Sep 2024

Immune checkpoint pathways in glioblastoma: a diverse and evolving landscape

in Cancer Immunity and Immunotherapy

Julio F. Inocencio
Stefan Mitrasinovic
Mohammad Asad
Ian F. Parney
Xingxing Zang
Benjamin T. Himes

Frontiers in Immunology

doi 10.3389/fimmu.2024.1424396

5,420 views
12 citations

Review

Published on 25 Oct 2022

Checkpoint inhibitors as immunotherapy for fungal infections: Promises, challenges, and unanswered questions

in Microbial Immunology

Sebastian Wurster
Stephanie S. Watowich
Dimitrios P. Kontoyiannis

Frontiers in Immunology

doi 10.3389/fimmu.2022.1018202

9,172 views
61 citations

Original Research

Published on 23 Dec 2024

Can there be calm during a cytokine storm? Immune checkpoint pathways affecting the severity of COVID-19 disease

in Virology

Matyas Meggyes
David U. Nagy
Ildiko Toth
Timoteus Feik
Agnes Peterfalvi
Beata Polgar
David Sipos
Agnes Kemeny
Laszlo Szereday

Frontiers in Microbiology

doi 10.3389/fmicb.2024.1508423

3,525 views
1 citation

Original Research

Published on 07 May 2021

TIGIT and PD-1 Immune Checkpoint Pathways Are Associated With Patient Outcome and Anti-Tumor Immunity in Glioblastoma

in Cancer Immunity and Immunotherapy

Itay Raphael
Rajeev Kumar
Lauren H. McCarl
Karsen Shoger
Lin Wang
Poorva Sandlesh
Chaim T. Sneiderman
Jordan Allen
Shuyan Zhai
Marissa Lynn Campagna

Frontiers in Immunology

doi 10.3389/fimmu.2021.637146

17,749 views
62 citations

Mini Review

Published on 24 Nov 2023

Immune checkpoints in rheumatoid arthritis: progress and promise

in Inflammation

Annabelle Small
Katie Lowe
Mihir D. Wechalekar

Frontiers in Immunology

doi 10.3389/fimmu.2023.1285554

8,031 views
9 citations

Perspective

Published on 11 Feb 2021

VISTA: A Target to Manage the Innate Cytokine Storm

in Immunological Tolerance and Regulation

Mohamed A. ElTanbouly
Yanding Zhao
Evelien Schaafsma
Christopher M. Burns
Rodwell Mabaera
Chao Cheng
Randolph J. Noelle

Frontiers in Immunology

doi 10.3389/fimmu.2020.595950

16,357 views
44 citations

Mini Review

Published on 04 Apr 2018

Targeting Tumor-Associated Macrophages as a Potential Strategy to Enhance the Response to Immune Checkpoint Inhibitors

in Molecular and Cellular Pathology

Luca Cassetta
Takanori Kitamura

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2018.00038

24,673 views
196 citations

Mini Review

Published on 23 Aug 2022

Mechanisms of extracellular vesicle-mediated immune evasion in melanoma

in Cancer Immunity and Immunotherapy

Lothar C. Dieterich

Frontiers in Immunology

doi 10.3389/fimmu.2022.1002551

5,958 views
16 citations

Review

Published on 26 Apr 2022

The Role of Innate Lymphoid Cells in Cancer Development and Immunotherapy

in Stem Cell Research

Rio Sugimura
Clement Yisai Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.803563

6,214 views
10 citations

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Review

Published on 15 Apr 2016

Immune Checkpoint Inhibitors and Prostate Cancer: A New Frontier?

Alessandra Modena
Chiara Ciccarese
Roberto Iacovelli
Matteo Brunelli
Rodolfo Montironi
Michelangelo Fiorentino
Giampaolo Tortora
Francesco Massari

Oncology Reviews

doi 10.4081/oncol.2016.293

Review

Published on 02 Aug 2024

The Nectin family ligands, PVRL2 and PVR, in cancer immunology and immunotherapy

in Cancer Immunity and Immunotherapy

Kosuke Murakami
Sudipto Ganguly

Frontiers in Immunology

doi 10.3389/fimmu.2024.1441730

9,333 views
12 citations

Review

Published on 17 Oct 2023

Checkpoint inhibition in hematologic malignancies

in Hematologic Malignancies

Aaron Tsumura
Daniel Levis
Joseph M. Tuscano

Frontiers in Oncology

doi 10.3389/fonc.2023.1288172

7,007 views
19 citations

Review

Published on 31 Aug 2021

Soluble B7-CD28 Family Inhibitory Immune Checkpoint Proteins and Anti-Cancer Immunotherapy

in Cancer Immunity and Immunotherapy

Muhammad Khan
Sumbal Arooj
Hua Wang

Frontiers in Immunology

doi 10.3389/fimmu.2021.651634

19,743 views
89 citations

Mini Review

Published on 14 Oct 2025

METTL14 in tumor immunity: epitranscriptomic regulation and therapeutic potential

in Cancer Immunity and Immunotherapy

Chunhong Li
Xiulin Jiang
Yixiao Yuan
Qiang Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1709742

2,303 views
3 citations

Review

Published on 05 Mar 2018

Combining Immunotherapy and Radiotherapy for Cancer Treatment: Current Challenges and Future Directions

in Cancer Molecular Targets and Therapeutics

Yifan Wang
Weiye Deng
Nan Li
Shinya Neri
Amrish Sharma
Wen Jiang
Steven H. Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2018.00185

82,485 views
355 citations

Articles

In or out of control: Modulating regulatory T cell homeostasis and function with immune checkpoint pathways

Immune checkpoint pathways in glioblastoma: a diverse and evolving landscape

Checkpoint inhibitors as immunotherapy for fungal infections: Promises, challenges, and unanswered questions

Can there be calm during a cytokine storm? Immune checkpoint pathways affecting the severity of COVID-19 disease

TIGIT and PD-1 Immune Checkpoint Pathways Are Associated With Patient Outcome and Anti-Tumor Immunity in Glioblastoma

Immune checkpoints in rheumatoid arthritis: progress and promise

VISTA: A Target to Manage the Innate Cytokine Storm

Targeting Tumor-Associated Macrophages as a Potential Strategy to Enhance the Response to Immune Checkpoint Inhibitors

Mechanisms of extracellular vesicle-mediated immune evasion in melanoma

The Role of Innate Lymphoid Cells in Cancer Development and Immunotherapy

Immune Checkpoint Inhibitors and Prostate Cancer: A New Frontier?

The Nectin family ligands, PVRL2 and PVR, in cancer immunology and immunotherapy

Checkpoint inhibition in hematologic malignancies

Soluble B7-CD28 Family Inhibitory Immune Checkpoint Proteins and Anti-Cancer Immunotherapy

METTL14 in tumor immunity: epitranscriptomic regulation and therapeutic potential

Combining Immunotherapy and Radiotherapy for Cancer Treatment: Current Challenges and Future Directions