Chemonucleolysis | List of Frontiers open access articles

Review

Published on 08 Jan 2025

Developments and clinical experiences in collagenase chemonucleolysis for lumbar disc herniation: a narrative review

in Precision Medicine

Hao Zhang
Chi Zhang
Lin Li
Ming-liang Hu
Jian-ning Zhao
Zhang Zheng
Wen-feng Ding

Frontiers in Medicine

doi 10.3389/fmed.2024.1522568

4,400 views
5 citations

Original Research

Published on 30 Aug 2023

Chemonucleolysis combined with dynamic loading for inducing degeneration in bovine caudal intervertebral discs

in Tissue Engineering and Regenerative Medicine

Andrea Vernengo
Helen Bumann
Nadine Kluser
Astrid Soubrier
Amra Šećerović
Jan Gewiess
Jan Ulrich Jansen
Cornelia Neidlinger-Wilke
Hans-Joachim Wilke
Sibylle Grad

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2023.1178938

4,069 views
14 citations

Original Research

Published on 13 Apr 2026

Effects of catheter-based extradural collagenase chemonucleolysis on pain scores and lumbar function in patients with lumbar disc herniation

in Intensive Care Medicine and Anesthesiology

Yongfu Feng
Yuanxin Huang
Jie Yuan
Guoping Song
Guanfeng Shang
Qian Zhang
Xiaoyun Luo
Yun Xu

Frontiers in Medicine

doi 10.3389/fmed.2026.1807178

293 views

Review

Published on 12 Jan 2026

Proteolytic enzyme models as tunable preclinical platforms for investigating intervertebral disc degeneration

in Molecular and Cellular Pathology

Jan Gewiess
Annamarie D’Intino
Alejandra Santos
Mauro Alini
Andrea J. Vernengo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1683282

1,017 views

Systematic Review

Published on 20 Jul 2021

Eight Surgical Interventions for Lumbar Disc Herniation: A Network Meta-Analysis on Complications

in Neurosurgery

Fei-Long Wei
Tian Li
Quan-You Gao
Yi Yang
Hao-Ran Gao
Ji-Xian Qian
Cheng-Pei Zhou

Frontiers in Surgery

doi 10.3389/fsurg.2021.679142

11,261 views
15 citations

Systematic Review

Published on 21 Aug 2023

The efficacy and safety of condoliase for lumbar disc herniation: a systematic review and meta-analysis

in Drugs Outcomes Research and Policies

Zeling Huang
Bo Xu
Yujiang Liu
Hua Chen
Xuefeng Cai
Long Zhang
Xiaofeng Shen
Yuwei Li

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1151998

8,532 views
11 citations

Articles