Clinical Trajectories | List of Frontiers open access articles

Brief Research Report

Published on 30 Oct 2024

Clinical trajectories of patients with multiple sclerosis from onset and their relationship with serum neurofilament light chain levels

in Multiple Sclerosis and Neuroimmunology

Carlos Quintanilla-Bordás
Laura Cubas-Núñez
Jéssica Castillo-Villalba
Sara Carratalá-Boscá
Raquel Gasque-Rubio
Jordi Tortosa-Carreres
Carmen Alcalá
Lorena Forés-Toribio
Celia Lucas
David Gorriz

Frontiers in Neurology

doi 10.3389/fneur.2024.1477335

2,169 views
3 citations

Study Protocol

Published on 29 Apr 2022

The Feasibility and Utility of Harnessing Digital Health to Understand Clinical Trajectories in Medication Treatment for Opioid Use Disorder: D-TECT Study Design and Methodological Considerations

in Addictive Disorders

Lisa A. Marsch
Ching-Hua Chen
Sara R. Adams
Asma Asyyed
Monique B. Does
Saeed Hassanpour
Emily Hichborn
Melanie Jackson-Morris
Nicholas C. Jacobson
Heather K. Jones

Frontiers in Psychiatry

doi 10.3389/fpsyt.2022.871916

7,898 views
12 citations

Case Report

Published on 17 Nov 2022

Case report: Real-world experience using a personalized cancer-specific circulating tumor DNA assay in different metastatic melanoma scenarios

in Skin Cancer

Karam Khaddour
Alice Zhou
Omar H. Butt
Griffin Budde
Allyson Koyen Malashevich
George Ansstas

Frontiers in Oncology

doi 10.3389/fonc.2022.978996

3,968 views
7 citations

Original Research

Published on 11 Jan 2024

Development and usability testing of a patient digital twin for critical care education: a mixed methods study

in Healthcare Professions Education

Lucrezia Rovati
Phillip J. Gary
Edin Cubro
Yue Dong
Oguz Kilickaya
Phillip J. Schulte
Xiang Zhong
Malin Wörster
Diana J. Kelm
Ognjen Gajic

Frontiers in Medicine

doi 10.3389/fmed.2023.1336897

7,614 views
25 citations

Original Research

Published on 09 Feb 2023

Comprehensive AI-assisted tool for ankylosing spondylitis based on multicenter research outperforms human experts

in Digital Public Health

Hao Li
Xiang Tao
Tuo Liang
Jie Jiang
Jichong Zhu
Shaofeng Wu
Liyi Chen
Zide Zhang
Chenxing Zhou
Xuhua Sun

Frontiers in Public Health

doi 10.3389/fpubh.2023.1063633

6,696 views
26 citations

Original Research

Published on 03 Dec 2018

Concussion Subtype Identification With the Rivermead Post-concussion Symptoms Questionnaire

in Neurotrauma

Jun Maruta
Angela Lumba-Brown
Jamshid Ghajar

Frontiers in Neurology

doi 10.3389/fneur.2018.01034

17,606 views
47 citations

Study Protocol

Published on 14 Jan 2026

PEPAMARKER: a multicenter cohort study protocol on predictive biomarkers of affective vs. non-affective trajectories in first-episode psychosis

in Schizophrenia

Raphaël Terrisse
Christophe Lemey
Deok-Hee Kim-Dufor
Louise Miglianico
Florian Stéphan

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1702187

628 views

Review

Accepted on 28 Feb 2026

Pediatric Heart Failure in the Era of Cardio-Immunology: Inflammatory–Immune Context Phenotypes, Diagnosis, and Targeted Management

in Molecular Innate Immunity

Danna Li
Dezhen Yao

Frontiers in Immunology

Original Research

Published on 04 Aug 2025

The Italian cross-cultural adaptation of the Social Vulnerability Index

in Aging and Public Health

Gloria Mangini
Cristina Festari
Silvia Ottaviani
Luca Tagliafico
Gianluca Di Cara
Alessio Nencioni
Fiammetta Monacelli
Delphi Consensus Panel

Frontiers in Public Health

doi 10.3389/fpubh.2025.1576223

2,246 views

Case Report

Published on 24 Jul 2025

Case Report: Clinical impact of BRCA1 and BRIP1 vs. BRCA1 and BRCA2 germline double heterozygosity in ovarian cancer: a comparative case study

in Gynecological Oncology

Limei Zheng
Qianyuan Zhu
Fenglan Zhang
Hao Qiu
Lan Qin
Jianhua Yang
Ming Qi

Frontiers in Oncology

doi 10.3389/fonc.2025.1614373

2,386 views

Hypothesis and Theory

Published on 20 Jul 2023

Suppressive myeloid cells in SARS-CoV-2 and Mycobacterium tuberculosis co-infection

in Microbial Immunology

Jane Alexandra Shaw
Stephanus T. Malherbe
Gerhard Walzl
Nelita du Plessis

Frontiers in Immunology

doi 10.3389/fimmu.2023.1222911

3,974 views
9 citations

Original Research

Published on 22 Feb 2021

Machine Learning Identifies Complicated Sepsis Course and Subsequent Mortality Based on 20 Genes in Peripheral Blood Immune Cells at 24 H Post-ICU Admission

in Inflammation

Shayantan Banerjee
Akram Mohammed
Hector R. Wong
Nades Palaniyar
Rishikesan Kamaleswaran

Frontiers in Immunology

doi 10.3389/fimmu.2021.592303

11,730 views
73 citations

Original Research

Published on 19 Nov 2025

Predicting progressive vision loss in glaucoma patients using functional principal component analysis and electronic health records

in Glaucoma

Rithvik Krishna Donnipadu
Maxim Sivolella
Cody Carroll
Sophia Y. Wang

Frontiers in Ophthalmology

doi 10.3389/fopht.2025.1632827

1,105 views

Case Report

Published on 26 Apr 2023

Case report: Acute liver failure in children and the human herpes virus 6-? A factor in the recent epidemic

in Pediatric Infectious Diseases

Suz Warner
Rachel M. Brown
Gary M. Reynolds
Zania Stamataki
Deirdre A. Kelly

Frontiers in Pediatrics

doi 10.3389/fped.2023.1143051

5,283 views
6 citations

Original Research

Published on 22 Mar 2019

Homo- and Heterotypic Trajectories in a Preschool to Primary-School Clinical Sample: A Prospective Study Related to Maternal Psychopathology

in Child and Adolescent Psychiatry

Isabell Jobs
Jörg Michael Müller
Olena Skorozhenina
Georg Romer

Frontiers in Psychiatry

doi 10.3389/fpsyt.2019.00153

3,963 views
4 citations

Review

Published on 02 Jun 2021

TAPAS: An Open-Source Software Package for Translational Neuromodeling and Computational Psychiatry

in Computational Psychiatry

Stefan Frässle
Eduardo A. Aponte
Saskia Bollmann
Kay H. Brodersen
Cao T. Do
Olivia K. Harrison
Samuel J. Harrison
Jakob Heinzle
Sandra Iglesias
Lars Kasper

Frontiers in Psychiatry

doi 10.3389/fpsyt.2021.680811

20,994 views
161 citations

Articles

Clinical trajectories of patients with multiple sclerosis from onset and their relationship with serum neurofilament light chain levels

The Feasibility and Utility of Harnessing Digital Health to Understand Clinical Trajectories in Medication Treatment for Opioid Use Disorder: D-TECT Study Design and Methodological Considerations

Case report: Real-world experience using a personalized cancer-specific circulating tumor DNA assay in different metastatic melanoma scenarios

Development and usability testing of a patient digital twin for critical care education: a mixed methods study

Comprehensive AI-assisted tool for ankylosing spondylitis based on multicenter research outperforms human experts

Concussion Subtype Identification With the Rivermead Post-concussion Symptoms Questionnaire

PEPAMARKER: a multicenter cohort study protocol on predictive biomarkers of affective vs. non-affective trajectories in first-episode psychosis

Pediatric Heart Failure in the Era of Cardio-Immunology: Inflammatory–Immune Context Phenotypes, Diagnosis, and Targeted Management

The Italian cross-cultural adaptation of the Social Vulnerability Index

Case Report: Clinical impact of BRCA1 and BRIP1 vs. BRCA1 and BRCA2 germline double heterozygosity in ovarian cancer: a comparative case study

Suppressive myeloid cells in SARS-CoV-2 and Mycobacterium tuberculosis co-infection

Machine Learning Identifies Complicated Sepsis Course and Subsequent Mortality Based on 20 Genes in Peripheral Blood Immune Cells at 24 H Post-ICU Admission

Predicting progressive vision loss in glaucoma patients using functional principal component analysis and electronic health records

Case report: Acute liver failure in children and the human herpes virus 6-? A factor in the recent epidemic

Homo- and Heterotypic Trajectories in a Preschool to Primary-School Clinical Sample: A Prospective Study Related to Maternal Psychopathology

TAPAS: An Open-Source Software Package for Translational Neuromodeling and Computational Psychiatry