Closed Loop System | List of Frontiers open access articles

Review

Published on 27 Feb 2026

Spatiotemporal immune gradients in gout: immune response–driven activation of the NLRP3–IL-1β axis and its transition to trained immunity

in Inflammation

Kang Wang
Jiabin Li
Jing Li
Fan Zeng
Siren Li
Pei Chen
Hui Xiong

Frontiers in Immunology

doi 10.3389/fimmu.2026.1776479

Case Report

Published on 27 Feb 2026

Case Report: A rare adult multisystem Langerhans cell histiocytosis involving the skin, thyroid, jaw-periodontal region, and bone: diagnostic challenges and complementary PET/CT–SPECT/CT findings

in Cancer Imaging and Image-directed Interventions

Longchuan Zhuang
Kexu Chen
Xiaokun Qi
Jie Li
Song Qin
Hua Yu
Minggang Yuan

Frontiers in Oncology

doi 10.3389/fonc.2026.1784088

Original Research

Published on 27 Feb 2026

Surgical management of retrosternal thyroid disease: a decennial retrospective analysis

in Thyroid Endocrinology

Francesco Quaglino
Domenico Galetta
Luca Cestino
Federico Festa
Sara Ruscio
Giulia Carbonaro
Marta Breda
Giorgia Gavello
Samuela Cannazza

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1739552

255 views

Original Research

Published on 27 Feb 2026

Beta cell function and insulin sensitivity during elexacaftor/tezacaftor/ivacaftor therapy in people with cystic fibrosis

in Clinical Diabetes

Laura Zazzeron
Valeria Grancini
Maddalena Trombetta
Gianfranco Alicandro
Maria Linda Boselli
Irene Cogliati
Giovanna Mantovani
Andrea Gramegna
Francesco Blasi
Riccardo C. Bonadonna

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1774728

Original Research

Published on 27 Feb 2026

Association between PFAS compounds in follicular fluid and POR and the intervention effect of Qizi Yusi Tang: a study based on targeted PFAS quantification analysis

in Reproduction

Hengbing Li
Jiacheng Li
Wenjing Jiang
Xin Hu
Zizhen Guo
Jingyan Song
Zhengao Sun

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1758118

Case Report

Published on 27 Feb 2026

Persistent lactic acidosis in ALK-positive anaplastic large cell lymphoma: a case report and literature review

in Hematologic Malignancies

Haoru Jin
Zhibin Xu
Qing Ai
Qiangwei Huang
Xu Chen
Yongbei Luo
Peicong Hong
Yuan Qiu

Frontiers in Oncology

doi 10.3389/fonc.2026.1744202

Original Research

Published on 27 Feb 2026

Serum osteopontin is associated with coronary plaque vulnerability and short-term cardiovascular events: a prospective cohort study

in Cardiovascular Endocrinology

Xingxing Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1771524

263 views

Original Research

Published on 27 Feb 2026

Global, regional and national burden of colon and rectum cancer attributable to high fasting plasma glucose: a systematic analysis for the Global Burden of Disease Study 2021

in Gastrointestinal Cancers: Colorectal Cancer

Ke Lu
Gang Xu

Frontiers in Oncology

doi 10.3389/fonc.2026.1690349

Original Research

Published on 27 Feb 2026

Mutant p53 and TP53 mutations in esophageal squamous cell carcinoma: consistency and diagnostic significance

in Cancer Genetics and Oncogenomics

Xueyu Zhuang
Na Lin
Yanjuan Xu

Frontiers in Genetics

doi 10.3389/fgene.2026.1680422

121 views

Mini Review

Published on 27 Feb 2026

Atrial fibrillation and acute myocardial infarction: a Two-Way relationship

in Thrombosis and Haemostasis

Arianna Pannunzio
Flavio Mastroianni
Laura Gatto
Pasquale Pignatelli
Francesco Prati
Daniele Pastori
Danilo Menichelli
Flavio Giuseppe Biccirè

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1699897

Original Research

Published on 27 Feb 2026

Consumer preferences and marketing model for certified blockchain products based on Sicilian ancient grains: authenticity, health, and ecosystem services

in Social Movements, Institutions and Governance

Marzia Ingrassia
Simona Bacarella
Stefania Chironi
Sandro Galluzzo
Giuseppe Russo

Frontiers in Sustainable Food Systems

doi 10.3389/fsufs.2026.1768230

116 views

Original Research

Published on 27 Feb 2026

The profile of a student’s sense of (un)safety at school: social, emotional, and academic dimensions

in Mental Health and Wellbeing in Education

Jolita Dudaitė
Jolanta Urbanovič
Romas Prakapas

Frontiers in Education

doi 10.3389/feduc.2026.1750772

Review

Published on 27 Feb 2026

Chronic nonbacterial osteomyelitis: a typical case and review

in Pediatric Orthopedics

Qiang Li
Yiwei Wang
Fei Liu
Pengfei Zheng

Frontiers in Pediatrics

doi 10.3389/fped.2026.1747342

139 views

Mini Review

Published on 27 Feb 2026

Transcranial stimulation as a possible therapeutic proposal in long COVID

in Interventions for Rehabilitation

Lidiane Palheta Miranda dos Santos
Julliana Vieira Leão
Ketelen Yasmim Braga de Moraes Silva
Danilo Lameira dos Santos
Chrisllane Nascimento Batista
Jonna Almeida Barros
Alna Carolina Mendes Paranhos
Ápio Ricardo Nazareth Dias
Luiz Fábio Magno Falcão

Frontiers in Rehabilitation Sciences

doi 10.3389/fresc.2026.1766757

Original Research

Published on 27 Feb 2026

Safety and probiotic characterization of Lacticaseibacillus rhamnosus SAL2: insights from integrated genomics and functional validation

in Food Microbiology

Jie Sun
Zhixue Li
Xinyi Lin
Jinlian Huang
Yamin Chen
Yuzhen Xu
Yanping Xu
Xueying Cheng
Ben Liu
Yongzhi Lun

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1767191

267 views

Original Research

Published on 27 Feb 2026

Bridging HIV prevention and sexual reproductive health services in the context of multi-method PrEP: a qualitative study exploring provider perceptions in South Africa

in Access and Barriers to Reproductive Health Services

Faith Mary Musvipwa
Siphokazi Dada
Fatima Abegail Cholo
Melanie Pleaner
Mosa Julia Letsielo
Sean Arries
Alison Kutywayo
Catherine Elizabeth Martin
Saiqa Mullick

Frontiers in Reproductive Health

doi 10.3389/frph.2026.1746212

Articles

Spatiotemporal immune gradients in gout: immune response–driven activation of the NLRP3–IL-1β axis and its transition to trained immunity

Case Report: A rare adult multisystem Langerhans cell histiocytosis involving the skin, thyroid, jaw-periodontal region, and bone: diagnostic challenges and complementary PET/CT–SPECT/CT findings

Surgical management of retrosternal thyroid disease: a decennial retrospective analysis

Beta cell function and insulin sensitivity during elexacaftor/tezacaftor/ivacaftor therapy in people with cystic fibrosis

Association between PFAS compounds in follicular fluid and POR and the intervention effect of Qizi Yusi Tang: a study based on targeted PFAS quantification analysis

Persistent lactic acidosis in ALK-positive anaplastic large cell lymphoma: a case report and literature review

Serum osteopontin is associated with coronary plaque vulnerability and short-term cardiovascular events: a prospective cohort study

Global, regional and national burden of colon and rectum cancer attributable to high fasting plasma glucose: a systematic analysis for the Global Burden of Disease Study 2021

Mutant p53 and TP53 mutations in esophageal squamous cell carcinoma: consistency and diagnostic significance

Atrial fibrillation and acute myocardial infarction: a Two-Way relationship

Consumer preferences and marketing model for certified blockchain products based on Sicilian ancient grains: authenticity, health, and ecosystem services

The profile of a student’s sense of (un)safety at school: social, emotional, and academic dimensions

Chronic nonbacterial osteomyelitis: a typical case and review

Transcranial stimulation as a possible therapeutic proposal in long COVID

Safety and probiotic characterization of Lacticaseibacillus rhamnosus SAL2: insights from integrated genomics and functional validation

Bridging HIV prevention and sexual reproductive health services in the context of multi-method PrEP: a qualitative study exploring provider perceptions in South Africa