Codon Deoptimization | List of Frontiers open access articles

Original Research

Published on 10 Oct 2023

Construction of pseudorabies virus variant attenuated vaccine: codon deoptimization of US3 and UL56 genes based on PRV gE/TK deletion strain

in Virology

Mengwei Xu
Laixu Zhu
Aimin Ge
Yamei Liu
Saisai Chen
Ziwen Wei
Yating Zheng
Ling Tong
Zhisheng Wang
Rongmei Fei

Frontiers in Microbiology

doi 10.3389/fmicb.2023.1248573

3,855 views
4 citations

Original Research

Accepted on 12 Feb 2026

Codon Deoptimization of Multispecific Biologics Reduces Mispairing During Transient Mammalian Protein Expression

in Synthetic Biology

Timothy Z. Chang
Weijun Ma
Jane Guo
Jiali Hu
Kalie Mix
Yi Tang
Karen Wong
Eva Bric-Furlong
Amanda Lennon
Brian Hall

Frontiers in Bioengineering and Biotechnology

100 views

Original Research

Published on 08 May 2019

Analysis of Nipah Virus Codon Usage and Adaptation to Hosts

in Virology

Rekha Khandia
Shailja Singhal
Utsang Kumar
Afzal Ansari
Ruchi Tiwari
Kuldeep Dhama
Jayashankar Das
Ashok Munjal
Raj Kumar Singh

Frontiers in Microbiology

doi 10.3389/fmicb.2019.00886

21,437 views
150 citations

Brief Research Report

Published on 06 Jul 2021

A Codon-Pair Bias Associated With Network Interactions in Influenza A, B, and C Genomes

in RNA

Ewan P. Plant
Zhiping Ye

Frontiers in Genetics

doi 10.3389/fgene.2021.699141

3,355 views
5 citations

Original Research

Published on 18 Oct 2021

Study on the Characteristic Codon Usage Pattern in Porcine Epidemic Diarrhea Virus Genomes and Its Host Adaptation Phenotype

in Virology

Fusheng Si
Li Jiang
Ruisong Yu
Wenqiang Wei
Zhen Li

Frontiers in Microbiology

doi 10.3389/fmicb.2021.738082

5,752 views
19 citations

Original Research

Published on 04 Jul 2025

Comprehensive analysis of the codon usage patterns in the polyprotein coding sequences of the honeybee viruses

in Veterinary Infectious Diseases

Yeşim Aktürk Dizman

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1567209

1,613 views
3 citations

Original Research

Published on 05 Nov 2020

Host Adaptation and Evolutionary Analysis of Zaire ebolavirus: Insights From Codon Usage Based Investigations

in Virology

Wen Luo
Ayan Roy
Fucheng Guo
David M. Irwin
Xuejuan Shen
Junbin Pan
Yongyi Shen

Frontiers in Microbiology

doi 10.3389/fmicb.2020.570131

5,587 views
21 citations

Original Research

Published on 21 Jan 2021

Use of Synonymous Deoptimization to Derive Modified Live Attenuated Strains of Foot and Mouth Disease Virus

in Virology

Fayna Diaz-San Segundo
Gisselle N. Medina
Edward Spinard
Anna Kloc
Elizabeth Ramirez-Medina
Paul Azzinaro
Steffen Mueller
Elizabeth Rieder
Teresa de los Santos

Frontiers in Microbiology

doi 10.3389/fmicb.2020.610286

8,603 views
10 citations

Original Research

Published on 02 Jul 2021

Edging on Mutational Bias, Induced Natural Selection From Host and Natural Reservoirs Predominates Codon Usage Evolution in Hantaan Virus

in Virology

Galal Ata
Hao Wang
Haoxiang Bai
Xiaoting Yao
Shiheng Tao

Frontiers in Microbiology

doi 10.3389/fmicb.2021.699788

4,725 views
19 citations

Articles

Construction of pseudorabies virus variant attenuated vaccine: codon deoptimization of US3 and UL56 genes based on PRV gE/TK deletion strain

Codon Deoptimization of Multispecific Biologics Reduces Mispairing During Transient Mammalian Protein Expression

Analysis of Nipah Virus Codon Usage and Adaptation to Hosts

A Codon-Pair Bias Associated With Network Interactions in Influenza A, B, and C Genomes

Study on the Characteristic Codon Usage Pattern in Porcine Epidemic Diarrhea Virus Genomes and Its Host Adaptation Phenotype

Comprehensive analysis of the codon usage patterns in the polyprotein coding sequences of the honeybee viruses

Host Adaptation and Evolutionary Analysis of Zaire ebolavirus: Insights From Codon Usage Based Investigations

Use of Synonymous Deoptimization to Derive Modified Live Attenuated Strains of Foot and Mouth Disease Virus

Edging on Mutational Bias, Induced Natural Selection From Host and Natural Reservoirs Predominates Codon Usage Evolution in Hantaan Virus