Combinatorial Therapy | List of Frontiers open access articles

Original Research

Published on 20 Nov 2023

Novel combinatorial therapy of oncolytic adenovirus AdV5/3-D24-ICOSL-CD40L with anti PD-1 exhibits enhanced anti-cancer efficacy through promotion of intratumoral T-cell infiltration and modulation of tumour microenvironment in mesothelioma mouse model

in Cancer Immunity and Immunotherapy

Mariangela Garofalo
Magdalena Wieczorek
Ines Anders
Monika Staniszewska
Michal Lazniewski
Marta Prygiel
Aleksandra Anna Zasada
Teresa Szczepińska
Dariusz Plewczynski
Stefano Salmaso

Frontiers in Oncology

doi 10.3389/fonc.2023.1259314

5,504 views
10 citations

Original Research

Published on 14 Jul 2021

The Basic Research of the Combinatorial Therapy of ABT-199 and Homoharringtonine on Acute Myeloid Leukemia

in Pharmacology of Anti-Cancer Drugs

Yuanfei Shi
Jing Ye
Ying Yang
Yanchun Zhao
Huafei Shen
Xiujin Ye
Wanzhuo Xie

Frontiers in Oncology

doi 10.3389/fonc.2021.692497

6,059 views
26 citations

Original Research

Published on 28 Sep 2023

Cabozantinib and IL-27 combinatorial therapy for bone-metastatic prostate cancer

in Cellular Biochemistry

Shreya Kumar
Grace E. Mulia
Marxa L. Figueiredo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1259336

6,065 views
8 citations

Original Research

Published on 05 Oct 2018

Nontoxic Targeting of Energy Metabolism in Preclinical VM-M3 Experimental Glioblastoma

in Clinical Nutrition

Zachary M. Augur
Catherine M. Doyle
Mingyi Li
Purna Mukherjee
Thomas N. Seyfried

Frontiers in Nutrition

doi 10.3389/fnut.2018.00091

12,761 views
16 citations

Original Research

Published on 15 Jul 2021

Targeting Thymidylate Synthase Enhances the Chemosensitivity of Triple-Negative Breast Cancer Towards 5-FU-Based Combinatorial Therapy

in Women's Cancer

Nair Hariprasad Haritha
Akbar Nawab
Vinod Vijayakurup
Nikhil Ponnoor Anto
Vijayasteltar B. Liju
Vijai V. Alex
Areekkara Nisthul Amrutha
Sreekumar U. Aiswarya
Mundanattu Swetha
Balachandran S. Vinod

Frontiers in Oncology

doi 10.3389/fonc.2021.656804

8,768 views
16 citations

Original Research

Published on 19 Jan 2026

A novel peptide oyster-derived antimicrobial peptide against clinical carbapenem-resistant Acinetobacter baumannii

in Marine Biotechnology and Bioproducts

Rui Hou
Yihua Cai
Shida Xu
Dandan Ma
Ning Su
Shanshan Wang
Hongmei Mo
Mian Peng

Frontiers in Marine Science

doi 10.3389/fmars.2025.1732660

1,045 views

Review

Published on 06 May 2025

Plant polysaccharides influence tumor development based on epigenetics: a review

in Pharmacology of Anti-Cancer Drugs

Cong Li
Yuao Hu
Hua Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1588857

4,035 views
4 citations

Review

Published on 16 Oct 2019

Novel and Alternative Targets Against Breast Cancer Stemness to Combat Chemoresistance

in Women's Cancer

Sangita Sridharan
Cory M. Howard
Augustus M. C. Tilley
Boopathi Subramaniyan
Amit K. Tiwari
Randall J. Ruch
Dayanidhi Raman

Frontiers in Oncology

doi 10.3389/fonc.2019.01003

10,016 views
47 citations

Review

Published on 29 Jun 2017

Bacteriocin-Antimicrobial Synergy: A Medical and Food Perspective

in Antimicrobials, Resistance and Chemotherapy

Harsh Mathur
Des Field
Mary C. Rea
Paul D. Cotter
Colin Hill
R. Paul Ross

Frontiers in Microbiology

doi 10.3389/fmicb.2017.01205

25,238 views
192 citations

Review

Published on 04 Oct 2019

Nanoparticles in the Treatment of Infections Caused by Multidrug-Resistant Organisms

in Translational Pharmacology

Nan-Yao Lee
Wen-Chien Ko
Po-Ren Hsueh

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01153

53,026 views
497 citations

Mini Review

Published on 22 Jun 2017

Systematic Review and Meta-Analysis of the Efficacy and Safety of Combined Epinephrine and Corticosteroid Therapy for Acute Bronchiolitis in Infants

in Respiratory Pharmacology

Kok P. Kua
Shaun W. H. Lee

Frontiers in Pharmacology

doi 10.3389/fphar.2017.00396

11,400 views
14 citations

Original Research

Published on 11 Nov 2020

Evaluation of Staphylococcal Bacteriophage Sb-1 as an Adjunctive Agent to Antibiotics Against Rifampin-Resistant Staphylococcus aureus Biofilms

in Antimicrobials, Resistance and Chemotherapy

Lei Wang
Tamta Tkhilaishvili
Andrej Trampuz
Mercedes Gonzalez Moreno

Frontiers in Microbiology

doi 10.3389/fmicb.2020.602057

7,272 views
40 citations

Original Research

Published on 04 Nov 2025

Metabolic subtyping reveals PDIK1L as a dual-functional regulator of progression and PARP inhibitor sensitivity in prostate cancer

in Cancer Cell Biology

Zhongyuan Wang
Qintao Ge
Anwaier Aihetaimujiang
Ji Zhang
Jiahe Lu
Jianfeng Yang
Yonghao Chen
Bin Qin
Hailiang Zhang
Wen-Hao Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1674844

1,839 views

Original Research

Published on 26 Aug 2020

Combination of a Gellan Gum-Based Hydrogel With Cell Therapy for the Treatment of Cervical Spinal Cord Injury

in Tissue Engineering and Regenerative Medicine

Eduardo D. Gomes
Biswarup Ghosh
Rui Lima
Miguel Goulão
Tiago Moreira-Gomes
Joana Martins-Macedo
Mark W. Urban
Megan C. Wright
Jeffrey M. Gimble
Nuno Sousa

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00984

6,660 views
14 citations

Review

Published on 27 Oct 2025

Pathophysiological mechanisms and emerging therapeutic strategies for muscle wasting: an integrative review

in Skeletal Physiology

Jiahao Huang
Tianshan Wen
Huijun Wei
Jiliang Kang
Junyue Lu
Taian Zhou
Youliang Wen
Haoyuan Huang

Frontiers in Physiology

doi 10.3389/fphys.2025.1674892

2,342 views
1 citation

Review

Published on 13 May 2021

Mesenchymal Epithelial Transition Factor Signaling in Pediatric Nervous System Tumors: Implications for Malignancy and Cancer Stem Cell Enrichment

in Molecular and Cellular Oncology

Amanda Rose Khater
Tamara Abou-Antoun

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.654103

6,997 views
10 citations

Articles

Novel combinatorial therapy of oncolytic adenovirus AdV5/3-D24-ICOSL-CD40L with anti PD-1 exhibits enhanced anti-cancer efficacy through promotion of intratumoral T-cell infiltration and modulation of tumour microenvironment in mesothelioma mouse model

The Basic Research of the Combinatorial Therapy of ABT-199 and Homoharringtonine on Acute Myeloid Leukemia

Cabozantinib and IL-27 combinatorial therapy for bone-metastatic prostate cancer

Nontoxic Targeting of Energy Metabolism in Preclinical VM-M3 Experimental Glioblastoma

Targeting Thymidylate Synthase Enhances the Chemosensitivity of Triple-Negative Breast Cancer Towards 5-FU-Based Combinatorial Therapy

A novel peptide oyster-derived antimicrobial peptide against clinical carbapenem-resistant Acinetobacter baumannii

Plant polysaccharides influence tumor development based on epigenetics: a review

Novel and Alternative Targets Against Breast Cancer Stemness to Combat Chemoresistance

Bacteriocin-Antimicrobial Synergy: A Medical and Food Perspective

Nanoparticles in the Treatment of Infections Caused by Multidrug-Resistant Organisms

Systematic Review and Meta-Analysis of the Efficacy and Safety of Combined Epinephrine and Corticosteroid Therapy for Acute Bronchiolitis in Infants

Evaluation of Staphylococcal Bacteriophage Sb-1 as an Adjunctive Agent to Antibiotics Against Rifampin-Resistant Staphylococcus aureus Biofilms

Metabolic subtyping reveals PDIK1L as a dual-functional regulator of progression and PARP inhibitor sensitivity in prostate cancer

Combination of a Gellan Gum-Based Hydrogel With Cell Therapy for the Treatment of Cervical Spinal Cord Injury

Pathophysiological mechanisms and emerging therapeutic strategies for muscle wasting: an integrative review

Mesenchymal Epithelial Transition Factor Signaling in Pediatric Nervous System Tumors: Implications for Malignancy and Cancer Stem Cell Enrichment