Constraint Based Models | List of Frontiers open access articles

Original Research

Published on 04 Mar 2026

Ascorbic acid enhances in vitro primordial germ cell-like cell differentiation from mouse ESCs

in Stem Cell Research

Umesh Kumar
Nithyapriya Kumar
P. Chandra Shekar
Kumarasamy Thangaraj

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1755998

403 views

Original Research

Published on 04 Mar 2026

Across preclinical and clinical platforms, approved and investigational psychiatric drugs share pathways and associate with similar molecular functions

in Technologies and Strategies to Enable Drug Discovery

Emily Su
Nico Matthew S. Valencia
Jarod Le
Emily Liu
Jennifer L. Wilson

Frontiers in Drug Discovery

doi 10.3389/fddsv.2025.1686789

708 views

Systematic Review

Published on 04 Mar 2026

A dual-database bibliometric analysis on dry needling for pain: Global trends and hotspots from web of science core collection and Scopus (2006–2025)

in Neuromuscular Disorders and Peripheral Neuropathies

Mo Liao
Xinhui Cheng
Fei Liu
Xingjuan Xiong
Yongsheng Yu

Frontiers in Neurology

doi 10.3389/fneur.2026.1713196

Original Research

Published on 04 Mar 2026

Association between metabolic syndrome, fatty liver disease, and gastrointestinal tumors: a population-based study with external validation

in Nutrition and Metabolism

Mengyao Zhang
Jie Song
Siqi Liu
Lanlan Yang
Qian Zhang
Zhenjing Jin

Frontiers in Nutrition

doi 10.3389/fnut.2026.1706013

Original Research

Published on 04 Mar 2026

Anti-inflammatory and antioxidant effects of dipotassium glycyrrhizinate in acute respiratory distress syndrome

in Pulmonary Medicine

Wei Cao
Dongjun Xu
Huijie Yu
Xuning Shen

Frontiers in Medicine

doi 10.3389/fmed.2026.1690322

137 views

Original Research

Published on 04 Mar 2026

Computed tomography–based analysis of external jugular vein cross–sectional area for vascular access in cats

in Veterinary Imaging

Daeyun Seo
Seong-tak Hong
Min-Su Kim
Taeho Oh

Frontiers in Veterinary Science

doi 10.3389/fvets.2026.1772712

Correction

Published on 04 Mar 2026

Correction: Enhancement of soil microbial community stability by earthworms and collembolans in soil from abandoned coal mine land

in Microbial Symbioses

Junli Jia
Linghui Chen
Qian Liu
Kai Wang
Kang Zhao
Xiaoyu Ren
Xue Gao
Jianmei An

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1803716

Correction

Published on 04 Mar 2026

Correction: Erythropoietin mitigates diabetic nephropathy by restoring PINK1/Parkin-mediated mitophagy

in Renal Pharmacology

Xinyao Yi
Wenhui Yan
Tingli Guo
Na Liu
Zhuanzhuan Wang
Jia Shang
Xiaotong Wei
Xin Cui
Yuzhuo Sun
Shuting Ren

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1781741

Systematic Review

Published on 04 Mar 2026

The clinical efficacy of pocket creation method ESD and conventional ESD in the treatment of early colorectal neoplasms: a meta-analysis

in Gastroenterology

Kegumei Jiekang
Linyue Zhang
Geng Chen

Frontiers in Medicine

doi 10.3389/fmed.2026.1724880

192 views

Original Research

Published on 04 Mar 2026

Dual - functional cRGD/pH - sensitive liposomes loaded with sorafenib: a novel therapeutic approach for hepatocellular carcinoma

in Biomedical Nanotechnology

Xu Yang
Guangchun Sun
Xiaoyu Zhou
Qing Liang
Jing Liu

Frontiers in Nanotechnology

doi 10.3389/fnano.2026.1760783

150 views

Original Research

Published on 04 Mar 2026

Characteristic analysis of the chloroplast genome of Cyathula capitata and comparative analysis with Cyathula officinalis and their hybrid Cyathula officinalis × Cyathula capitata

in Plant Genetics, Epigenetics and Chromosome Biology

Bixing Gao
Yisha Zeng
Min Tang
Maohua Yuan
Ke Deng
Yan Gou
Guihua Jiang

Frontiers in Plant Science

doi 10.3389/fpls.2026.1772997

Mini Review

Published on 04 Mar 2026

Bridging ethnobotany and neuro-pharmacology: exploring South Africa’s indigenous plants for brain health

in Biological Activities of Natural Products

Madira C. Manganyi
Jeffrey Lebepe
Nana Millicent Duduzile Buthelezi

Frontiers in Natural Products

doi 10.3389/fntpr.2026.1734095

Original Research

Published on 04 Mar 2026

Colonic biopsy-associated microbial signatures are predictive of response to anti-TNFα biological therapy in Crohn’s disease

in Clinical and Diagnostic Microbiology and Immunology

Konstantina Zafeiropoulou
Ishtu L. Hageman
Tianqi Mu
Mark Davids
Andrew Y. F. Li Yim
Vincent W. Joustra
Theodorus B. M. Hakvoort
Jack Satsangi
Konstantinos Chronas
Pim J. Koelink

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2026.1741002

133 views

Original Research

Published on 04 Mar 2026

Integrative biology shows DPP4 affects inflammatory response to eclampsia and cell model growth via p65/NLRP3/ASC/Caspase-1 pathway

in Immunogenetics

Zhimin Bian
Li Hao
Rongjuan Yang
Jianghui Sun

Frontiers in Genetics

doi 10.3389/fgene.2026.1775026

137 views

Case Report

Published on 04 Mar 2026

Co-occurring DMD, GJA1, and novel FYCO1 variants in a proband from a consanguineous oculodentodigital dysplasia family: a rare multi-locus case report

in Genetics of Common and Rare Diseases

Kondyarpu Abhishek
Nitish Kumar Mohanta
Joseph John
Swarupa Panda
Amit Kumar Satapathy
Roma Rattan
Puppala Venkat Ramchander

Frontiers in Genetics

doi 10.3389/fgene.2026.1753212

270 views

Systematic Review

Published on 04 Mar 2026

Efficacy and safety of neuromodulation and multimodal therapies for traumatic brain injury-induced disorders of consciousness: an updated umbrella review

in Neurorehabilitation

Xia Yang
Yongbiao Li
Nana Zhang
Dongwei Luo
Chunying Zhao
Qingshan Liu

Frontiers in Neurology

doi 10.3389/fneur.2026.1742096

107 views

Articles

Ascorbic acid enhances in vitro primordial germ cell-like cell differentiation from mouse ESCs

Across preclinical and clinical platforms, approved and investigational psychiatric drugs share pathways and associate with similar molecular functions

A dual-database bibliometric analysis on dry needling for pain: Global trends and hotspots from web of science core collection and Scopus (2006–2025)

Association between metabolic syndrome, fatty liver disease, and gastrointestinal tumors: a population-based study with external validation

Anti-inflammatory and antioxidant effects of dipotassium glycyrrhizinate in acute respiratory distress syndrome

Computed tomography–based analysis of external jugular vein cross–sectional area for vascular access in cats

Correction: Enhancement of soil microbial community stability by earthworms and collembolans in soil from abandoned coal mine land

Correction: Erythropoietin mitigates diabetic nephropathy by restoring PINK1/Parkin-mediated mitophagy

The clinical efficacy of pocket creation method ESD and conventional ESD in the treatment of early colorectal neoplasms: a meta-analysis

Dual - functional cRGD/pH - sensitive liposomes loaded with sorafenib: a novel therapeutic approach for hepatocellular carcinoma

Characteristic analysis of the chloroplast genome of Cyathula capitata and comparative analysis with Cyathula officinalis and their hybrid Cyathula officinalis × Cyathula capitata

Bridging ethnobotany and neuro-pharmacology: exploring South Africa’s indigenous plants for brain health

Colonic biopsy-associated microbial signatures are predictive of response to anti-TNFα biological therapy in Crohn’s disease

Integrative biology shows DPP4 affects inflammatory response to eclampsia and cell model growth via p65/NLRP3/ASC/Caspase-1 pathway

Co-occurring DMD, GJA1, and novel FYCO1 variants in a proband from a consanguineous oculodentodigital dysplasia family: a rare multi-locus case report

Efficacy and safety of neuromodulation and multimodal therapies for traumatic brain injury-induced disorders of consciousness: an updated umbrella review