Culture Conversion | List of Frontiers open access articles

Original Research

Published on 22 Apr 2021

Comparative Utility of Genetic Determinants of Drug Resistance and Phenotypic Drug Susceptibility Profiling in Predicting Clinical Outcomes in Patients With Multidrug-Resistant Mycobacterium tuberculosis

in Family Medicine and Primary Care

Yang Che
Tianchi Yang
Lv Lin
Yue Xiao
Feng Jiang
Yanfei Chen
Tong Chen
Jifang Zhou

Frontiers in Public Health

doi 10.3389/fpubh.2021.663974

3,634 views
2 citations

Original Research

Published on 22 Mar 2022

In-Depth Immunophenotyping With Mass Cytometry During TB Treatment Reveals New T-Cell Subsets Associated With Culture Conversion

in Microbial Immunology

Carole Chedid
Thibault Andrieu
Eka Kokhreidze
Nestani Tukvadze
Samanta Biswas
Md. Fahim Ather
Mohammad Khaja Mafij Uddin
Sayera Banu
Flavio De Maio
Giovanni Delogu

Frontiers in Immunology

doi 10.3389/fimmu.2022.853572

6,737 views
14 citations

Original Research

Published on 01 Apr 2021

Effect of Inflammatory Cytokines/Chemokines on Pulmonary Tuberculosis Culture Conversion and Disease Severity in HIV-Infected and -Uninfected Individuals From South Africa

in Microbial Immunology

Santhuri Rambaran
Kogieleum Naidoo
Lara Lewis
Razia Hassan-Moosa
Dhineshree Govender
Natasha Samsunder
Thomas J. Scriba
Nesri Padayatchi
Aida Sivro

Frontiers in Immunology

doi 10.3389/fimmu.2021.641065

6,863 views
19 citations

Original Research

Published on 05 Jun 2024

Evaluation of time to sputum smear conversion and its association with treatment outcomes among drug-resistant tuberculosis patients: a retrospective record-reviewing study

in Drugs Outcomes Research and Policies

Abdulaziz Ibrahim Alzarea
Amna Saifullah
Yusra Habib Khan
Adullah Salah Alanazi
Ahmed D. Alatawi
Majed Ahmed Algarni
Ziyad Saeed Almalki
Abdullah K. Alahmari
Hassan H. Alhassan
Tauqeer Hussain Mallhi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1370344

2,707 views
2 citations

Original Research

Published on 27 Mar 2023

Population pharmacokinetics and model-based dosing evaluation of bedaquiline in multidrug-resistant tuberculosis patients

in Pharmacology of Infectious Diseases

Ge Shao
Ziwei Bao
Lina Davies Forsman
Jakob Paues
Jim Werngren
Katarina Niward
Thomas Schön
Judith Bruchfeld
Jan-Willem Alffenaar
Yi Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1022090

5,913 views
11 citations

Review

Published on 10 Feb 2023

Advancing personalized medicine for tuberculosis through the application of immune profiling

in Clinical and Diagnostic Microbiology and Immunology

Vo Thuy Anh Thu
Ly Da Dat
Rannissa Puspita Jayanti
Hoang Kim Tu Trinh
Tran Minh Hung
Yong-Soon Cho
Nguyen Phuoc Long
Jae-Gook Shin

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2023.1108155

7,733 views
16 citations

Clinical Trial

Published on 29 Sep 2025

Delamanid-containing regimens over 24 weeks for the treatment of multidrug-resistant/rifampicin-resistant tuberculosis: preliminary results from a single center in a multicenter, prospective, observational study

in Pulmonary Medicine

Fuping Yang
Mingdan Yin
Xingmei Jiang
Xing Zhao
Xuemei An
Yan Liu
Yijia Yuan

Frontiers in Medicine

doi 10.3389/fmed.2025.1631030

2,134 views

Review

Published on 03 Jun 2024

Treatment for non-tuberculous mycobacteria: challenges and prospects

in Infectious Agents and Disease

Liberty E. Conyers
Bernadette M. Saunders

Frontiers in Microbiology

doi 10.3389/fmicb.2024.1394220

26,563 views
48 citations

Original Research

Published on 30 Sep 2025

Study on cerebrospinal fluid meropenem, vancomycin and tigecycline monitoring in patients with central nervous system infection following neurosurgery under different drug regimens

in Drug Metabolism and Transport

Xiaoman Zhao
Yanan Qiao
Qing Xie
Zheng Zhang
Yan Song
Jianbang Kang
Jinchuan Li
Jinju Duan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1666168

2,958 views

Original Research

Published on 28 Aug 2020

Increased Neutrophil Count and Decreased Neutrophil CD15 Expression Correlate With TB Disease Severity and Treatment Response Irrespective of HIV Co-infection

in Microbial Immunology

Lerato N. Ndlovu
Lauren Peetluk
Sashen Moodley
Shepherd Nhamoyebonde
Abigail T. Ngoepe
Matilda Mazibuko
Khadija Khan
Farina Karim
Alexander S. Pym
Fernanda Maruri

Frontiers in Immunology

doi 10.3389/fimmu.2020.01872

9,063 views
24 citations

Original Research

Published on 25 Oct 2018

Frequency of Circulating CD4+Ki67+HLA-DR− T Regulatory Cells Prior to Treatment for Multidrug Resistant Tuberculosis Can Differentiate the Severity of Disease and Predict Time to Culture Conversion

in Microbial Immunology

Selena Ferrian
Melinda Ross
Francesca Conradie
Shaheed Vally Omar
Nazir Ismail
Francesca Little
Gilla Kaplan
Dorothy Fallows
Clive M. Gray

Frontiers in Immunology

doi 10.3389/fimmu.2018.02438

9,406 views
8 citations

Original Research

Published on 16 May 2018

Amikacin Liposome Inhalation Suspension (ALIS) Penetrates Non-tuberculous Mycobacterial Biofilms and Enhances Amikacin Uptake Into Macrophages

in Antimicrobials, Resistance and Chemotherapy

Jimin Zhang
Franziska Leifer
Sasha Rose
Dung Yu Chun
Jill Thaisz
Tracey Herr
Mary Nashed
Jayanthi Joseph
Walter R. Perkins
Keith DiPetrillo

Frontiers in Microbiology

doi 10.3389/fmicb.2018.00915

23,141 views
167 citations

Original Research

Published on 20 Jun 2023

Treatment outcomes of multidrug-resistant tuberculosis patients receiving ambulatory treatment in Shenzhen, China: a retrospective cohort study

in Infectious Diseases: Epidemiology and Prevention

Ji Lecai
Peierdun Mijiti
Hong Chuangyue
Gao Qian
Tan Weiguo
Chen Jihong

Frontiers in Public Health

doi 10.3389/fpubh.2023.1134938

5,565 views
16 citations

Original Research

Published on 07 Aug 2025

Whole-genome sequencing and machine learning reveal key drivers of delayed sputum conversion in rifampicin-resistant tuberculosis

in Clinical and Diagnostic Microbiology and Immunology

Qing Fang
Xiangchen Li
Yewei Lu
Junshun Gao
Yvette Wu
Yi Chen
Yang Che

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1641385

2,247 views

Original Research

Published on 12 Nov 2025

Tigecycline pharmacodynamics in the hollow fiber system of Mycobacterium avium-complex lung disease and the utility of MICs and time-kill studies in drug development

in Pharmacology of Infectious Diseases

Devyani Deshpande
Shashikant Srivastava
Tawanda Gumbo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1682477

1,014 views

Original Research

Published on 10 Jan 2019

Imbalance of NET and Alpha-1-Antitrypsin in Tuberculosis Patients Is Related With Hyper Inflammation and Severe Lung Tissue Damage

in Microbial Immunology

Mayla Gabryele Miranda de Melo
Eliene Denites Duarte Mesquita
Martha M. Oliveira
Caio da Silva-Monteiro
Anna K. A. Silveira
Thiago S. Malaquias
Tatiana C. P. Dutra
Rafael M. Galliez
Afrânio L. Kritski
Elisangela C. Silva

Frontiers in Immunology

doi 10.3389/fimmu.2018.03147

7,503 views
51 citations

Articles

Comparative Utility of Genetic Determinants of Drug Resistance and Phenotypic Drug Susceptibility Profiling in Predicting Clinical Outcomes in Patients With Multidrug-Resistant Mycobacterium tuberculosis

In-Depth Immunophenotyping With Mass Cytometry During TB Treatment Reveals New T-Cell Subsets Associated With Culture Conversion

Effect of Inflammatory Cytokines/Chemokines on Pulmonary Tuberculosis Culture Conversion and Disease Severity in HIV-Infected and -Uninfected Individuals From South Africa

Evaluation of time to sputum smear conversion and its association with treatment outcomes among drug-resistant tuberculosis patients: a retrospective record-reviewing study

Population pharmacokinetics and model-based dosing evaluation of bedaquiline in multidrug-resistant tuberculosis patients

Advancing personalized medicine for tuberculosis through the application of immune profiling

Delamanid-containing regimens over 24 weeks for the treatment of multidrug-resistant/rifampicin-resistant tuberculosis: preliminary results from a single center in a multicenter, prospective, observational study

Treatment for non-tuberculous mycobacteria: challenges and prospects

Study on cerebrospinal fluid meropenem, vancomycin and tigecycline monitoring in patients with central nervous system infection following neurosurgery under different drug regimens

Increased Neutrophil Count and Decreased Neutrophil CD15 Expression Correlate With TB Disease Severity and Treatment Response Irrespective of HIV Co-infection

Frequency of Circulating CD4+Ki67+HLA-DR− T Regulatory Cells Prior to Treatment for Multidrug Resistant Tuberculosis Can Differentiate the Severity of Disease and Predict Time to Culture Conversion

Amikacin Liposome Inhalation Suspension (ALIS) Penetrates Non-tuberculous Mycobacterial Biofilms and Enhances Amikacin Uptake Into Macrophages

Treatment outcomes of multidrug-resistant tuberculosis patients receiving ambulatory treatment in Shenzhen, China: a retrospective cohort study

Whole-genome sequencing and machine learning reveal key drivers of delayed sputum conversion in rifampicin-resistant tuberculosis

Tigecycline pharmacodynamics in the hollow fiber system of Mycobacterium avium-complex lung disease and the utility of MICs and time-kill studies in drug development

Imbalance of NET and Alpha-1-Antitrypsin in Tuberculosis Patients Is Related With Hyper Inflammation and Severe Lung Tissue Damage

Delamanid-containing regimens over 24 weeks for the treatment of multidrug-resistant/rifampicin-resistant tuberculosis: preliminary results from a single center in a multicenter, prospective, observational study