Deep Space | List of Frontiers open access articles

Review

Published on 12 Feb 2026

Heat shock proteins (Hsp70 and Hsp90) in neurodegeneration: pathogenic roles and therapeutic potential

in Cellular and Molecular Mechanisms of Brain-aging

Noureddine Ben Khalaf

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1711422

437 views

Original Research

Published on 12 Feb 2026

Baseline glucose-to-lymphocyte ratio predicts nivolumab outcomes in advanced non-small cell lung cancer: a multicenter retrospective study

in Cancer Immunity and Immunotherapy

Mustafa Ersoy
Umut Kefeli
Devrim Cabuk
Ertugrul Bayram
Duygu Bayir
Oktay Bozkurt
Muslih Ürün
Ramazan Coşar
Teoman Sakalar
Emel Mutlu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1714533

390 views

Original Research

Published on 12 Feb 2026

Integrative transcriptomic and metabolomic analysis reveals the molecular basis of leaf variegation in Cymbidium ensifolium

in Plant Bioinformatics

Yu Jiang
Jin Wang
Xuliang Tu
Min Zhong
Bin Wan

Frontiers in Plant Science

doi 10.3389/fpls.2026.1712811

377 views

Methods

Published on 12 Feb 2026

Label-free TIMING: an efficient, reliable and scalable AI workflow for automated profiling of cell-cell interaction behaviors in nanowell arrays

in Computational BioImaging

Anuj S. Todkar
Shyam Reddy Kotha
Lin Bai
Saikiran Mandula
Hannah B. Wilson
Daniel D. Meyer
Rebecca Berdeaux
Badrinath Roysam
Navin Varadarajan

Frontiers in Bioinformatics

doi 10.3389/fbinf.2026.1711797

695 views

Original Research

Published on 12 Feb 2026

Identification and validation of prognostic genes related to glycolysis and M2 macrophage in hepatocellular carcinoma: an integrated analysis of bulk RNA sequencing and single-cell RNA sequencing

in Cancer Immunity and Immunotherapy

Anqi Wang
Lina You
Ming Zuo
Zhanao He
Hong Yang
Wukui Huang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1710411

481 views

Original Research

Published on 12 Feb 2026

Evaluation of extravascular lung water and cardiac function by intrapartum bedside ultrasound: full-term preeclampsia vs. healthy controls

in Hypertension

Shi-jie Zhang
Shao-zheng He
Jing-jing Wu
Yong-jian Chen
Guo-rong Lyu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1709378

249 views

Review

Published on 12 Feb 2026

Oxysterol signaling in the central nervous system: cellular mechanisms and implications for neurodegeneration

in Brain Disease Mechanisms

Raphael P. Ricci
Cheng Xiang Foo
Katharina Ronacher
Carlie L. Cullen

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2026.1709065

300 views

Original Research

Published on 12 Feb 2026

Beyond the logo: Sanitas' experience in advancing inclusive sports mindset through Paralympic sponsorship

in Sports Management, Marketing, and Economics

Olga Kolotouchkina
Luis Leardy
Javier Pérez-Tejero

Frontiers in Sports and Active Living

doi 10.3389/fspor.2026.1718212

679 views

Original Research

Published on 12 Feb 2026

Digital eye health and behavioral determinants of screen use among university students in the UAE

in Health Communications and Behavior Change

Mohamed Anas Patni
Wafeeqa Fatima
Maitha Abdulla Alshamsi
Hawa Ali Jama
Mohammad Shafeeq
Rikhil Rajiv
Mouhamad Soubhi Alsoued
Biji Thomas George
Rasha Aziz Attia Salama
Abdalla Ahmed Eldaw Elamin

Frontiers in Digital Health

doi 10.3389/fdgth.2026.1719475

410 views

Original Research

Published on 12 Feb 2026

Subsequent vertebral fracture after percutaneous vertebroplasty or kyphoplasty in postmenopausal women with osteoporotic vertebral compression fracture

in Bone Research

Qianru Zhang
Yuanpei Cheng
Fengling Chen

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1716002

199 views

Original Research

Published on 12 Feb 2026

Work-related well-being among hepatobiliary surgical nurses: a structural equation modeling study

in Public Mental Health

Yu Wang
Lina Zhou
Yun Guo

Frontiers in Public Health

doi 10.3389/fpubh.2026.1772238

207 views

Original Research

Published on 12 Feb 2026

Enhancing antioxidant capacity via NRF2 pathway activation to mitigate heat stress‐induced oxidative damage in bovine granulosa cells, oocytes, and embryos

in Embryonic Development

Ghyslaine G. Ramírez
Ahmed Gad
Nico G. Menjivar
Scott Burlingham
Ming-Hao Cheng
Thomas W. Chen
Soham Ghosh
Dawit Tesfaye

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1777760

652 views

Review

Published on 12 Feb 2026

Targeting ferroptosis with culinary spices: a dietary strategy for neuroprotection via the Nrf2/GPX4 axis

in Nutrition, Psychology and Brain Health

Wei Hong
Yingjie Qing
Jie Liu

Frontiers in Nutrition

doi 10.3389/fnut.2026.1779927

567 views

Editorial

Published on 12 Feb 2026

Editorial: Targeted drug delivery and mode of action of small molecules in neuroinflammation

in Drug Metabolism and Transport

Vishal S. Patil
Pukar Khanal
Darasaguppe R. Harish

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1782890

445 views

Mini Review

Published on 12 Feb 2026

Beyond the Th2 paradigm: CD4+ cytotoxic T lymphocytes as key drivers of tissue damage and fibrosis in IgG4-related disease

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Jiayang Yi
Lanlan Jia
Tongjun Mao
Zhi Li

Frontiers in Immunology

doi 10.3389/fimmu.2026.1781462

290 views

Systematic Review

Published on 12 Feb 2026

Comparison of probiotics to lactulose for minimal hepatic encephalopathy in patients with cirrhosis: a meta-analysis of randomized controlled trials

in Hepatobiliary Diseases

Qiufeng He
Zhili Chen
Yang Deng
Chuangjie Mao
Yue Fan

Frontiers in Medicine

doi 10.3389/fmed.2026.1780891

263 views

Articles

Heat shock proteins (Hsp70 and Hsp90) in neurodegeneration: pathogenic roles and therapeutic potential

Baseline glucose-to-lymphocyte ratio predicts nivolumab outcomes in advanced non-small cell lung cancer: a multicenter retrospective study

Integrative transcriptomic and metabolomic analysis reveals the molecular basis of leaf variegation in Cymbidium ensifolium

Label-free TIMING: an efficient, reliable and scalable AI workflow for automated profiling of cell-cell interaction behaviors in nanowell arrays

Identification and validation of prognostic genes related to glycolysis and M2 macrophage in hepatocellular carcinoma: an integrated analysis of bulk RNA sequencing and single-cell RNA sequencing

Evaluation of extravascular lung water and cardiac function by intrapartum bedside ultrasound: full-term preeclampsia vs. healthy controls

Oxysterol signaling in the central nervous system: cellular mechanisms and implications for neurodegeneration

Beyond the logo: Sanitas' experience in advancing inclusive sports mindset through Paralympic sponsorship

Digital eye health and behavioral determinants of screen use among university students in the UAE

Subsequent vertebral fracture after percutaneous vertebroplasty or kyphoplasty in postmenopausal women with osteoporotic vertebral compression fracture

Work-related well-being among hepatobiliary surgical nurses: a structural equation modeling study

Enhancing antioxidant capacity via NRF2 pathway activation to mitigate heat stress‐induced oxidative damage in bovine granulosa cells, oocytes, and embryos

Targeting ferroptosis with culinary spices: a dietary strategy for neuroprotection via the Nrf2/GPX4 axis

Editorial: Targeted drug delivery and mode of action of small molecules in neuroinflammation

Beyond the Th2 paradigm: CD4+ cytotoxic T lymphocytes as key drivers of tissue damage and fibrosis in IgG4-related disease

Comparison of probiotics to lactulose for minimal hepatic encephalopathy in patients with cirrhosis: a meta-analysis of randomized controlled trials