Defense Signaling Pathways | List of Frontiers open access articles

Original Research

Published on 05 Nov 2025

Sintilimab plus a bevacizumab biosimilar (IBI305) in advanced HCC with Child-Pugh A/B liver function: a real-world multicenter retrospective study

in Cancer Immunity and Immunotherapy

Yuanxu Zhang
Youhan Miao
Wei Sun
Yixing Yu
Jinjing Wang
Shuang Xiao
Shengwei Lu
Xia Wang
Yang Li
Xiucheng Pan

Frontiers in Oncology

doi 10.3389/fonc.2025.1681663

501 views

Review

Published on 05 Nov 2025

Cytokines in sepsis: a critical review of the literature on systemic inflammation and multiple organ dysfunction

in Cytokines and Soluble Mediators in Immunity

Roberta Vella
Diego Panci
Francesco Carini
Ginevra Malta
Salvatore Vieni
Sabrina David
Giuseppe Davide Albano
Maria Puntarello
Stefania Zerbo
Antonina Argo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1682306

682 views

Original Research

Published on 05 Nov 2025

From recognition to expression: extending cardiovascular emotional dampening to facial expressions under elevated blood pressure

in Social Neuroscience

Shatabdi Bhowmick
Meenakshi Shukla
Rakesh Pandey

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1681377

521 views

Systematic Review

Published on 05 Nov 2025

Physical literacy among older adults: a scoping review of definition, attributes, contributing factors, consequences and interventions

in Aging and Public Health

Yawei Yu
Yu Duan
Hong Guo
Yiping Chen

Frontiers in Public Health

doi 10.3389/fpubh.2025.1678171

964 views

Original Research

Published on 05 Nov 2025

Identification of glycolysis-related clusters and immune cell infiltration in hepatic fibrosis progression using machine learning models and experimental validation

in Inflammation

Guanglin Xiao
Zhiling Deng
Ke Qiu
Aoyi Li
Xingyue Yi
Hong Ren

Frontiers in Immunology

doi 10.3389/fimmu.2025.1684937

511 views

Original Research

Published on 05 Nov 2025

Redistributive effects of China's urban–rural resident basic medical insurance: a theoretical model and empirical analysis

in Health Economics

Wenfang Ji
Fuling Chu
Yi Qin

Frontiers in Public Health

doi 10.3389/fpubh.2025.1689510

564 views

Original Research

Published on 05 Nov 2025

Association of TNF-α polymorphisms rs1800629 (−308G>A) and rs361525 (−238G>A) with type 2 diabetes mellitus in the Punjabi population of Pakistan

in Diabetes: Molecular Mechanisms

Muhammad Waqar
Tsai-Sung Tai
Abdul Qadeer
Umar Aziz
Mohammad Abohassan
Chien-Chin Chen
Sawar Khan

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1664411

498 views

Review

Published on 05 Nov 2025

Organizational routines and the possibilities for racial equity in test-optional admissions

in Leadership in Education

Kelly E. Slay

Frontiers in Education

doi 10.3389/feduc.2025.1659953

292 views

Review

Published on 05 Nov 2025

Genomics in plant pathogen identification and control

in Plant Pathogen Interactions

Nkechi Gloria Ogbuji
Josephine Udunma Agogbua

Frontiers in Plant Science

doi 10.3389/fpls.2025.1661432

513 views

Review

Published on 05 Nov 2025

Vision toolkit part 2. features and metrics for assessing oculomotor signal: a review

in Integrative Physiology

Quentin Laborde
Axel Roques
Allan Armougum
Nicolas Vayatis
Ioannis Bargiotas
Laurent Oudre

Frontiers in Physiology

doi 10.3389/fphys.2025.1661026

881 views

Original Research

Published on 05 Nov 2025

Comparison in trends and outcomes of multiple vs. single arterial coronary bypass graft surgery

in Cardiovascular Surgery

Qiuju Ding
Han Li
Xiaofeng Cheng
Min Ge
Qing Zhou

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1661006

415 views

Original Research

Published on 05 Nov 2025

Functional partitioning through competitive learning

in Machine Learning and Artificial Intelligence

Marius Tacke
Matthias Busch
Kevin Linka
Christian Cyron
Roland Aydin

Frontiers in Artificial Intelligence

doi 10.3389/frai.2025.1661444

399 views

Original Research

Published on 05 Nov 2025

Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms

in NK and Innate Lymphoid Cell Biology

Lillia A. Baird
Samuel J. Teener
Ian F. Webber-Davis
Andrew D. Carter
Fang Huang
Dae-Gyu Jang
Joshua P. Famie
Caroline E. Piecuch
Kai Guo
Eva L. Feldman

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662197

318 views

Original Research

Published on 05 Nov 2025

Effects of adverse childhood experiences and personal resilience on household emergency preparedness: considerations for disaster planning

in Life-Course Epidemiology and Social Inequalities in Health

Tara Heagele
William Ellery Samuels
Sarah Kaplan
Lisa Wilcox
Taryn Amberson
Charleen McNeill
Lavonne M. Adams

Frontiers in Public Health

doi 10.3389/fpubh.2025.1652564

521 views

Original Research

Published on 05 Nov 2025

Rodent home cage monitoring for preclinical safety pharmacology assessment: results of a multi-company validation evaluating nonclinical and clinical data from three compounds

in Regulatory Toxicology

R. R. Sillito
J. Sutherland
A. Milne
C. Giuliano
C. Sigfridsson
M. Rolf
A. K. Cherian
M. McClafferty
E. I. Rossman
G. Teuns

Frontiers in Toxicology

doi 10.3389/ftox.2025.1655330

1,013 views

Case Report

Published on 05 Nov 2025

Fulminant necrotizing fasciitis secondary to Aeromonas dhakensis infection: a case report

in Infectious Diseases: Pathogenesis and Therapy

Xiaoxia Li
Juanxian Gu
Weifang Zhang
Qinhua Zhang
Zebin Fang
Bin Jin
Zhenfei Ou
Xiao Huang

Frontiers in Medicine

doi 10.3389/fmed.2025.1685528

149 views

Articles

Sintilimab plus a bevacizumab biosimilar (IBI305) in advanced HCC with Child-Pugh A/B liver function: a real-world multicenter retrospective study

Cytokines in sepsis: a critical review of the literature on systemic inflammation and multiple organ dysfunction

From recognition to expression: extending cardiovascular emotional dampening to facial expressions under elevated blood pressure

Physical literacy among older adults: a scoping review of definition, attributes, contributing factors, consequences and interventions

Identification of glycolysis-related clusters and immune cell infiltration in hepatic fibrosis progression using machine learning models and experimental validation

Redistributive effects of China's urban–rural resident basic medical insurance: a theoretical model and empirical analysis

Association of TNF-α polymorphisms rs1800629 (−308G>A) and rs361525 (−238G>A) with type 2 diabetes mellitus in the Punjabi population of Pakistan

Organizational routines and the possibilities for racial equity in test-optional admissions

Genomics in plant pathogen identification and control

Vision toolkit part 2. features and metrics for assessing oculomotor signal: a review

Comparison in trends and outcomes of multiple vs. single arterial coronary bypass graft surgery

Functional partitioning through competitive learning

Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms

Effects of adverse childhood experiences and personal resilience on household emergency preparedness: considerations for disaster planning

Rodent home cage monitoring for preclinical safety pharmacology assessment: results of a multi-company validation evaluating nonclinical and clinical data from three compounds

Fulminant necrotizing fasciitis secondary to Aeromonas dhakensis infection: a case report