Design Considerations | List of Frontiers open access articles

Case Report

Published on 08 Oct 2025

Case report: Anlotinib plus oral etoposide: a potential salvage therapy based on insights from EGFR-TKI-resistant SCLC transformation PDX and clinical settings

in Thoracic Oncology

Zixi Wang
Xiaoyu Li
Lili Jiang
Weiya Wang
Kai Xiao
Ting Zhang
Li Li
Dan Li
Yongsheng Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1661273

496 views

Review

Published on 08 Oct 2025

Metabolic regulation of interferon-mediated innate antiviral immunity

in Viral Immunology

Tian Zhong
Qi Cao
Zhiyue Ma
Caiyu Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1680688

713 views

Original Research

Published on 08 Oct 2025

Genetic reinstatement of RIG-I in chickens reveals insights into avian immune evolution and influenza interaction

in Comparative Immunology

Hicham Sid
Theresa von Heyl
Sabrina Schleibinger
Romina Klinger
Leah Heymelot Nabel
Hanna Vikkula
Rodrigo Guabiraba
Vanaique Guillory
Ryan Scicluna
Mohanned Naif Alhussien

Frontiers in Immunology

doi 10.3389/fimmu.2025.1680791

783 views

Original Research

Published on 08 Oct 2025

Ribosome biogenesis-related gene signature predicts prognosis and immune landscape in glioma and identifies UTP20 as a therapeutic target

in Cancer Immunity and Immunotherapy

Yadan Li
Xiaolong Tang
Wenhui Zhao
Xiuwen Si
Yanfang Cui
Yanbin Dong
Yongshuo Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1680667

360 views

Original Research

Published on 08 Oct 2025

Prediction of compressive strength of high-performance concrete based on multiple machine learning models

in Structural Materials

Kouchen Xiao
Hongjian Zhang
Sijia Wei
Chuanxin Zhu
Jingtong He
Shuai Zhu
Xiaohan Yang

Frontiers in Materials

doi 10.3389/fmats.2025.1698248

469 views

Case Report

Published on 08 Oct 2025

Case Report: Efficacy of preoperative conversion therapy with lenvatinib, toripalimab, and hepatic arterial infusion chemotherapy in an advanced hepatocellular carcinoma

in Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

Jing Mao
Hengzhi Zhang
Xingxia Yang
Yanjun Yao
Xu Sun
Qiang Yan

Frontiers in Oncology

doi 10.3389/fonc.2025.1627281

646 views

Original Research

Published on 08 Oct 2025

Beyond mindfulness: the importance of body compassion in colorectal cancer distress

in Psycho-Oncology

Lauren A. Zimmaro
Aimee J. Christie
Andrew Nicklawsky
Jennifer K. Altman
James W. Carson
Christopher H. Lieu
Carolyn Y. Fang
Jennifer B. Reese

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1618389

2,536 views

Original Research

Published on 08 Oct 2025

Analysis of influential factors in laparoscopic myomectomy and estimation of hidden blood loss

in Obstetrics and Gynecological Surgery

Jingjing Lu
Lili Chu
Liliang Shen

Frontiers in Surgery

doi 10.3389/fsurg.2025.1614919

442 views

Original Research

Published on 08 Oct 2025

Trustworthy navigation with variational policy in deep reinforcement learning

in Robot Learning and Evolution

Karla Bockrath
Liam Ernst
Rohaan Nadeem
Bryan Pedraza
Dimah Dera

Frontiers in Robotics and AI

doi 10.3389/frobt.2025.1652050

1,019 views

Original Research

Published on 08 Oct 2025

Development and validation of a novel UPLC-Q-Orbitrap HRMS method for determining p-Nitroaniline and its metabolites in blood

in Analytical Chemistry

Peng Wang
Junlin Wang
Qiuliang Xu
Hua Zou
Xiangjing Gao
Hong Ren
Yiyao Cao

Frontiers in Chemistry

doi 10.3389/fchem.2025.1631203

614 views

Case Report

Published on 08 Oct 2025

Diagnosis and therapeutic strategies for primary bladder mucinous adenocarcinoma: a case report and literature review

in Genitourinary Oncology

Xi Cheng
Weibo Wang
Lexing Yang
Supeng Tai
Junyue Tao
Yao Fu
Jun Zhou

Frontiers in Oncology

doi 10.3389/fonc.2025.1652375

565 views

Original Research

Published on 08 Oct 2025

Enhancing mathematical communication and Islamic values in Islamic and regular schools through interactive worksheets

in STEM Education

Rahmah Johar
M. Ikhsan
Zahratul Idami
Cut Khairunnisak
Ellianti Ellianti
Ulya Rohaizati
Munirah Ghazali

Frontiers in Education

doi 10.3389/feduc.2025.1633056

247 views

Original Research

Published on 08 Oct 2025

LEM-UNet: an edge-guided network for 3D multimodal images segmentation in focal cortical dysplasia

in Brain Imaging Methods

Qiunan Li
Hao Yu
Manli Zhang
Xiaotong Yuan
Lixin Cai
Guixia Kang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1634606

849 views

Original Research

Published on 08 Oct 2025

Risk factors and model construction for early neurological deterioration in patients with intracerebral hemorrhage

in Neurological Biomarkers

Heng Zhou
Dapeng Dai
Kang Xie
Aimin Li

Frontiers in Neurology

doi 10.3389/fneur.2025.1663347

525 views

Original Research

Published on 08 Oct 2025

Novel Immune biomarkers for the early stratification of oligoarthritis patients at risk of developing polyarticular extension

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Federica Raggi
Simone Pelassa
Francesca Antonini
Chiara Rossi
Federica Briasco
Silvia Maria Orsi
Genny Del Zotto
Davide Cangelosi
Angelo Ravelli
Marco Gattorno

Frontiers in Immunology

doi 10.3389/fimmu.2025.1663663

650 views

Case Report

Published on 08 Oct 2025

Case Report: Esophago-pleural fistula found by the squamous cells from pleural effusion

in Gastrointestinal Cancers: Gastric and Esophageal Cancers

Shu Li
Zesen Han
Xue Zhang
Qihui Ge
Yingying Zhao
Shaojuan Lv
Min Li
Yongchao Zhu

Frontiers in Oncology

doi 10.3389/fonc.2025.1647915

514 views

Articles

Case report: Anlotinib plus oral etoposide: a potential salvage therapy based on insights from EGFR-TKI-resistant SCLC transformation PDX and clinical settings

Metabolic regulation of interferon-mediated innate antiviral immunity

Genetic reinstatement of RIG-I in chickens reveals insights into avian immune evolution and influenza interaction

Ribosome biogenesis-related gene signature predicts prognosis and immune landscape in glioma and identifies UTP20 as a therapeutic target

Prediction of compressive strength of high-performance concrete based on multiple machine learning models

Case Report: Efficacy of preoperative conversion therapy with lenvatinib, toripalimab, and hepatic arterial infusion chemotherapy in an advanced hepatocellular carcinoma

Beyond mindfulness: the importance of body compassion in colorectal cancer distress

Analysis of influential factors in laparoscopic myomectomy and estimation of hidden blood loss

Trustworthy navigation with variational policy in deep reinforcement learning

Development and validation of a novel UPLC-Q-Orbitrap HRMS method for determining p-Nitroaniline and its metabolites in blood

Diagnosis and therapeutic strategies for primary bladder mucinous adenocarcinoma: a case report and literature review

Enhancing mathematical communication and Islamic values in Islamic and regular schools through interactive worksheets

LEM-UNet: an edge-guided network for 3D multimodal images segmentation in focal cortical dysplasia

Risk factors and model construction for early neurological deterioration in patients with intracerebral hemorrhage

Novel Immune biomarkers for the early stratification of oligoarthritis patients at risk of developing polyarticular extension

Case Report: Esophago-pleural fistula found by the squamous cells from pleural effusion