Deterministic Optimization | List of Frontiers open access articles

Original Research

Published on 07 May 2026

Sequential versus concurrent neoadjuvant immunochemotherapy in locally advanced esophageal squamous cell carcinoma: a randomized, controlled, open-label, phase 2 trial (HCHTOG1906)

in Cancer Immunity and Immunotherapy

Yan Zheng
Jiwei Wu
Lingdi Zhao
Yaxing Shen
Guanghui Liang
Keting Li
Quanli Gao
Wenqun Xing

Frontiers in Immunology

doi 10.3389/fimmu.2026.1770662

202 views

Review

Published on 07 May 2026

EV-associated non-coding RNAs in paediatric asthma airway remodelling: current mechanistic evidence and therapeutic perspectives

in Respiratory Pharmacology

Yaling Liu
Dan Wang
Hu Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1820574

222 views

Original Research

Published on 07 May 2026

Clinical experience with eravacycline-based combination therapy for carbapenem-resistant Acinetobacter baumannii pneumonia: a prospective observational case series

in Pharmacology of Infectious Diseases

Ying Xiao
Yu Cheng
Xiaohong Xu
Hongqiang Qiu
Xuanxi Huang
Zhiqiang Xue
Meili Cai
Qing Wang
Yanmei Guo
Hui Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1796494

216 views

Review

Published on 07 May 2026

Neurodevelopmental disorders and the gut microbiome: insights into ADHD and tic disorders

in Microorganisms in Vertebrate Digestive Systems

Jiawen Li
Xinyi Qiu

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1779746

275 views

Original Research

Published on 07 May 2026

Emergency response for maritime sudden cardiac death: framework for pre-hospital rescue procedures and analysis of clinical characteristics

in Cardiac Rhythmology

Jinru Li
Mingqiu Hu
Tongyu Wang
Yanhao Xie
Yi Liu
Jian Yao
Xiangyu Yan
Haojun Fan

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1700421

326 views

Original Research

Published on 07 May 2026

Deviations from the inverse relationship between tumor and normal tissue dose and RBE in fast neutron data are compatible with the presence of hypoxia, with possible applications to hypo-fractionated proton therapy

in Radiation Oncology

Bleddyn Jones

Frontiers in Oncology

doi 10.3389/fonc.2026.1792868

221 views

Review

Published on 07 May 2026

Metabolic and post-translational modifications in sepsis-associated immune dysfunction: a conceptual framework

in Inflammation

Mingze Xu
Ziye Zhang
Min Zhu
Sen Zhang
Juxin Deng
Zhaoyang Du
Zhenjie Wang
Hongchang Zhao
Zhaolei Qiu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1820993

228 views

Systematic Review

Published on 07 May 2026

Permanent facial palsy and recurrence rate after surgery for benign parotid tumors: pairwise and network meta-analysis of different parotid surgery techniques

in Otorhinolaryngology - Head and Neck Surgery

Caroline Bernhard
Peter Schlattmann
Orlando Guntinas-Lichius

Frontiers in Surgery

doi 10.3389/fsurg.2026.1836835

290 views

Original Research

Published on 07 May 2026

Study on mechanical behavior of steel fiber reinforced high strength concrete five-pile caps

in Structural Materials

Jie Lei
Shuo Li
Guodong Zhang
Jinyong Yang
Shuaiqi Song
Weifeng Bai

Frontiers in Materials

doi 10.3389/fmats.2026.1814311

229 views

Original Research

Published on 07 May 2026

Joint security and energy optimization in UAV-enabled smart grid networks

in Interdisciplinary Physics

Jian Wu
Xiaowei Hao
Junwei Ma
Yang Li

Frontiers in Physics

doi 10.3389/fphy.2026.1817865

209 views

Case Report

Published on 07 May 2026

Case Report: A case of diffuse subretinal fibrosis and uveitis syndrome with vitreoretinal traction syndrome

in Ophthalmology

Xiaohua Zhang
Yongping Hu
Jian Li

Frontiers in Medicine

doi 10.3389/fmed.2026.1671793

193 views

Original Research

Published on 07 May 2026

The relationship between positive relationships and fear of loneliness on the academic engagement of Peruvian university students

in Psychology in Education

Jonatán Padilla-Guevara
Jhordy Andy Irene-Mendoza
Luz Keyli Goycochea-Rodrigo
Joel Palomino-Ccasa
Jhordan Mayta-Llanos
Julio Cjuno

Frontiers in Education

doi 10.3389/feduc.2026.1793974

282 views

Review

Published on 07 May 2026

Sepsis in end-stage liver disease and acute-on-chronic liver failure: pathophysiology, diagnostic challenges, and pharmacological management

in Pharmacology of Infectious Diseases

Jacopo Belfiore
Riccardo Taddei
Lorenzo Roberto Suardi

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1775585

282 views

Original Research

Published on 07 May 2026

ATP13A2 promoted cell stemness, cisplatin resistance, autophagy, and cell progression of bladder cancer

in Cancer Immunity and Immunotherapy

Chenxi Zhu
Jinjin Lu
Biqiang Zhu
Bing Liu
Guohao Li
Yonglian Guo
Xiaoyan Guo
Zhuo Yin

Frontiers in Immunology

doi 10.3389/fimmu.2026.1743064

191 views

Case Report

Published on 07 May 2026

Case Report: Primary sciatic leiomyosarcoma in a patient with neurofibromatosis type 1

in Surgical Oncology

Longgang Chen
Meiling Xu
Kai Cheng
Lingya Cui
Xuefei Mou
Changhui Li

Frontiers in Oncology

doi 10.3389/fonc.2026.1682808

153 views

Policy and Practice Reviews

Published on 07 May 2026

The movement imperative: reimagining healthcare through the lens of human movement

in Physical Activity in the Prevention and Management of Disease

Madhur Mangalam
Jessica Fabianiak

Frontiers in Sports and Active Living

doi 10.3389/fspor.2026.1667847

244 views

Articles

Sequential versus concurrent neoadjuvant immunochemotherapy in locally advanced esophageal squamous cell carcinoma: a randomized, controlled, open-label, phase 2 trial (HCHTOG1906)

EV-associated non-coding RNAs in paediatric asthma airway remodelling: current mechanistic evidence and therapeutic perspectives

Clinical experience with eravacycline-based combination therapy for carbapenem-resistant Acinetobacter baumannii pneumonia: a prospective observational case series

Neurodevelopmental disorders and the gut microbiome: insights into ADHD and tic disorders

Emergency response for maritime sudden cardiac death: framework for pre-hospital rescue procedures and analysis of clinical characteristics

Deviations from the inverse relationship between tumor and normal tissue dose and RBE in fast neutron data are compatible with the presence of hypoxia, with possible applications to hypo-fractionated proton therapy

Metabolic and post-translational modifications in sepsis-associated immune dysfunction: a conceptual framework

Permanent facial palsy and recurrence rate after surgery for benign parotid tumors: pairwise and network meta-analysis of different parotid surgery techniques

Study on mechanical behavior of steel fiber reinforced high strength concrete five-pile caps

Joint security and energy optimization in UAV-enabled smart grid networks

Case Report: A case of diffuse subretinal fibrosis and uveitis syndrome with vitreoretinal traction syndrome

The relationship between positive relationships and fear of loneliness on the academic engagement of Peruvian university students

Sepsis in end-stage liver disease and acute-on-chronic liver failure: pathophysiology, diagnostic challenges, and pharmacological management

ATP13A2 promoted cell stemness, cisplatin resistance, autophagy, and cell progression of bladder cancer

Case Report: Primary sciatic leiomyosarcoma in a patient with neurofibromatosis type 1

The movement imperative: reimagining healthcare through the lens of human movement