Dichloroacetate Dca | List of Frontiers open access articles

Case Report

Published on 07 Oct 2016

Fatal Liver and Bone Marrow Toxicity by Combination Treatment of Dichloroacetate and Artesunate in a Glioblastoma Multiforme Patient: Case Report and Review of the Literature

in Pharmacology of Anti-Cancer Drugs

Martin Uhl
Stefan Schwab
Thomas Efferth

Frontiers in Oncology

doi 10.3389/fonc.2016.00204

9,189 views
27 citations

Original Research

Published on 25 Sep 2023

Metabolic reprogramming induced by DCA enhances cisplatin sensitivity through increasing mitochondrial oxidative stress in cholangiocarcinoma

in Pharmacology of Anti-Cancer Drugs

Hanjiao Qin
Ge Zheng
Qiao Li
Luyan Shen

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1128312

4,504 views
17 citations

Original Research

Published on 13 Jul 2023

Antineoplastic effects of sodium dichloroacetate and omeprazole, alone or in combination, on canine oral mucosal melanoma cells

in Oncology in Veterinary Medicine

Gabriela F. Toledo
Marcia K. Nagamine
Victor Nowosh
Felippe T. Machado
Cristina O. Massoco
Nadja C. Souza-Pinto
Maria L. Z. Dagli

Frontiers in Veterinary Science

doi 10.3389/fvets.2023.1186650

3,684 views
3 citations

Original Research

Published on 17 May 2019

Sodium Dichloroacetate Stimulates Angiogenesis by Improving Endothelial Precursor Cell Function in an AKT/GSK-3β/Nrf2 Dependent Pathway in Vascular Dementia Rats

in Neuropharmacology

Hui Zhao
Junqin Mao
Yuan Yuan
Jingjing Feng
Hao Cheng
Guorong Fan
Yuefan Zhang
Tiejun Li

Frontiers in Pharmacology

doi 10.3389/fphar.2019.00523

10,467 views
21 citations

Original Research

Published on 06 Sep 2021

Pyruvate Dehydrogenase Kinase Inhibitor Dichloroacetate Improves Host Control of Salmonella enterica Serovar Typhimurium Infection in Human Macrophages

in Microbial Immunology

Cassandra L. R. van Doorn
Gina K. Schouten
Suzanne van Veen
Kimberley V. Walburg
Jeroen J. Esselink
Matthias T. Heemskerk
Frank Vrieling
Tom H. M. Ottenhoff

Frontiers in Immunology

doi 10.3389/fimmu.2021.739938

6,923 views
19 citations

Mini Review

Published on 17 Mar 2023

In-vivo magnetic resonance spectroscopy of lactate as a non-invasive biomarker of dichloroacetate activity in cancer and non-cancer central nervous system disorders

in Cancer Molecular Targets and Therapeutics

David O. Kamson
Viveka Chinnasamy
Stuart A. Grossman
Chetan Bettegowda
Peter B. Barker
Peter W. Stacpoole
Georg Oeltzschner

Frontiers in Oncology

doi 10.3389/fonc.2023.1077461

4,872 views
9 citations

Review

Published on 07 Mar 2013

Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology

in Molecular and Cellular Oncology

Gopinath Sutendra
Evangelos D. Michelakis

Frontiers in Oncology

doi 10.3389/fonc.2013.00038

41,998 views
243 citations

Original Research

Published on 11 Oct 2022

Disturbance of the Warburg effect by dichloroacetate and niclosamide suppresses the growth of different sub-types of malignant pleural mesothelioma in vitro and in vivo

in Pharmacology of Anti-Cancer Drugs

Sze-Kwan Lam
Sheng Yan
Joyce Sze-Man Lam
Yuqian Feng
Mahjabin Khan
Caoyang Chen
Frankie Chi-Fat Ko
James Chung-Man Ho

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1020343

4,895 views
5 citations

Original Research

Published on 25 May 2022

Heterogeneous Expression and Subcellular Localization of Pyruvate Dehydrogenase Complex in Prostate Cancer

in Genitourinary Oncology

Caroline E. Nunes-Xavier
Janire Mingo
Maite Emaldi
Karine Flem-Karlsen
Gunhild M. Mælandsmo
Øystein Fodstad
Roberto Llarena
José I. López
Rafael Pulido

Frontiers in Oncology

doi 10.3389/fonc.2022.873516

7,097 views
16 citations

Articles

Fatal Liver and Bone Marrow Toxicity by Combination Treatment of Dichloroacetate and Artesunate in a Glioblastoma Multiforme Patient: Case Report and Review of the Literature

Metabolic reprogramming induced by DCA enhances cisplatin sensitivity through increasing mitochondrial oxidative stress in cholangiocarcinoma

Antineoplastic effects of sodium dichloroacetate and omeprazole, alone or in combination, on canine oral mucosal melanoma cells

Sodium Dichloroacetate Stimulates Angiogenesis by Improving Endothelial Precursor Cell Function in an AKT/GSK-3β/Nrf2 Dependent Pathway in Vascular Dementia Rats

Pyruvate Dehydrogenase Kinase Inhibitor Dichloroacetate Improves Host Control of Salmonella enterica Serovar Typhimurium Infection in Human Macrophages

In-vivo magnetic resonance spectroscopy of lactate as a non-invasive biomarker of dichloroacetate activity in cancer and non-cancer central nervous system disorders

Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology

Disturbance of the Warburg effect by dichloroacetate and niclosamide suppresses the growth of different sub-types of malignant pleural mesothelioma in vitro and in vivo

Heterogeneous Expression and Subcellular Localization of Pyruvate Dehydrogenase Complex in Prostate Cancer