Drug Design And Development | List of Frontiers open access articles

Original Research

Accepted on 07 Oct 2025

A Reverse Network Pharmacology and Bioinformatics-Based Approach to Exploring Medication Patterns for Polycystic Ovary Syndrome-Related Infertility

in Obstetrics and Gynecology

Yueyan Wang
Fan Jia
Jing Hu
Zhiqi Shi
Haixia Huang
Yahong Zhou

Frontiers in Medicine

doi 10.3389/fmed.2025.1614165

Original Research

Accepted on 07 Oct 2025

A characterization study on electroencephalographic changes and lateralization of functional brain connectivity in boys with developmental coordination disorder

in Pediatric Neurology

Song Yiqi
Li Zhenpeng
Xiaotong Zhu
Hou Juanyi
Liu Shiji
Xie Yi
Xie Yongtao

Frontiers in Neurology

doi 10.3389/fneur.2025.1591236

Editorial

Accepted on 07 Oct 2025

Editorial: Vascular Dysfunction and Endocrine Disorders: Unraveling Interactions, Mechanisms, and Clinical Implications

in Cellular Endocrinology

Zhice Xu
Hong Liu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1714212

Original Research

Accepted on 07 Oct 2025

Biallelic variants in the UTRN gene cause a novel form of multiple congenital arthrogryposis

in Genetics of Common and Rare Diseases

Evgeniya Melnik
Daria Akimova
Tatiana Markova
Eugene Tatarskiy
Anna Tvorogova
Viktoria Zabnenkova
Vladimir Kenis
Olga Agranovich
Mikhail Skoblov
Elena Dadali

Frontiers in Genetics

doi 10.3389/fgene.2025.1664424

Original Research

Accepted on 07 Oct 2025

High Incidence and Poor Prognosis of Bone Metastases in Functioning Small Intestinal Neuroendocrine Tumors

in Cancer Endocrinology

Annie Mathew
Pia Hauptmeier
Schaarschmidt M Benedikt
Wolfgang P Fendler
Dagmar Führer
Harald Lahner

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1680209

Original Research

Accepted on 07 Oct 2025

Exploring the Molecular Mechanism of EGCG in Preventing Obesity-induced Precocious Puberty Based on Serum Metabolomics and Molecular Docking

in Nutrition and Metabolism

Shiyu Gao
Lina Xia
Chenzhenghao Jiang
Bang Shao
Ying Shao
Xiaojing Li
Peiying Wu
Jieyi He
Qiuju Du
Lingwei Liang

Frontiers in Nutrition

doi 10.3389/fnut.2025.1675535

128 views

Original Research

Accepted on 07 Oct 2025

Psychological Resilience and Music Performance Anxiety: Exploring Mediators and Sex Differences in Chinese Choir Members

in Performance Science

Hao Du
Yanchang Liu
Jian Sun

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1703571

Original Research

Accepted on 07 Oct 2025

Oxidative low-density lipoprotein and shear induced calcification within a calcific aortic valve disease-on-a-chip platform

in Heart Valve Disease

Melissa Mendoza
Mei-Hsiu Chen
Peter Huang
Gretchen J. Mahler

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1655341

132 views

Original Research

Accepted on 07 Oct 2025

TyG × Waist Circumference Composite Indicator and Cardiovascular Disease Risk in Older Adults Across Multiple Regions: A Cross-Sectional Study

in Cardiovascular Endocrinology

Ying Guo
Jietao Zhang
Tong Chen
Yan Wang
Fanqi Geng
Hongjian Jia

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1687289

Original Research

Accepted on 07 Oct 2025

Genetic susceptibility to gestational diabetes and its mild modification by bisphenol A and thyroid-stimulating hormone: Findings from a South Chinese pregnancy cohort

in Nutrition and Metabolism

Yanyan MAO
Zhaofeng Zhang
Yupei Shen
Min Li
Xiaoping Fei
Difei Wang
QianXi ZHU
Xiaohong Chen
Jing Du

Frontiers in Nutrition

doi 10.3389/fnut.2025.1652265

Original Research

Accepted on 07 Oct 2025

Meat processing wastewater; the use of Lemna minor L. to convert an environmental burden into a new resource

in Water and Wastewater Management

Merve Sasmaz Kislioglu
Alexandra Katsara
Cian Redmond
Wiebke Drenckhan
Marcel A.K. Jansen

Frontiers in Environmental Science

doi 10.3389/fenvs.2025.1622266

195 views

Original Research

Accepted on 07 Oct 2025

Multilevel factors affecting mental health literacy among older adults: a qualitative study based on social ecological model

in Public Mental Health

Yan Wang
Shoumei Jia
Anni Wang
Huiyuan Li
Rongjing Xu
Xuyan He

Frontiers in Public Health

doi 10.3389/fpubh.2025.1656116

102 views

Original Research

Accepted on 07 Oct 2025

Dose Response Test of Patient-derived Cancer Organoids to Irradiation

in Radiation Oncology

Haina Yu
Canfeng Lin
Lifeng Chen
Weizhen Liu
Hualong Liu
Jing Li
Ye Yao

Frontiers in Oncology

doi 10.3389/fonc.2025.1677172

Original Research

Accepted on 07 Oct 2025

3D-Printed PEEK versus Conventional Free Fibula Flap for Jaw Reconstruction: A Comparative Clinical Study

in Head and Neck Cancer

Feng Dongdong
Zhang Yuxiang
Haiwei Guo
Zheng Chuanming
Zhang Yining
Wanchen Zhang
Lai Fangyuan
Jiajie Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1656914

Original Research

Accepted on 07 Oct 2025

Remimazolam used for sedation during spinal anesthesia puncture provides faster sedation effect and increase recovery rate compared to midazolam: a randomized controlled trial

in Drugs Outcomes Research and Policies

PeiPei Sun
Zhimin Tan
Lianxiong Liang
Jianbo Zhang
Xiaoqiang Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1685312

Mini Review

Accepted on 07 Oct 2025

Risk Stratification and Survival Prediction in Heart Failure: From Grades to Scores

in Heart Failure and Transplantation

Sidie Huang
Wen Zhang
Yidi Zeng
Yun Long
Hao Liang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1676441

Articles

A Reverse Network Pharmacology and Bioinformatics-Based Approach to Exploring Medication Patterns for Polycystic Ovary Syndrome-Related Infertility

A characterization study on electroencephalographic changes and lateralization of functional brain connectivity in boys with developmental coordination disorder

Editorial: Vascular Dysfunction and Endocrine Disorders: Unraveling Interactions, Mechanisms, and Clinical Implications

Biallelic variants in the UTRN gene cause a novel form of multiple congenital arthrogryposis

High Incidence and Poor Prognosis of Bone Metastases in Functioning Small Intestinal Neuroendocrine Tumors

Exploring the Molecular Mechanism of EGCG in Preventing Obesity-induced Precocious Puberty Based on Serum Metabolomics and Molecular Docking

Psychological Resilience and Music Performance Anxiety: Exploring Mediators and Sex Differences in Chinese Choir Members

Oxidative low-density lipoprotein and shear induced calcification within a calcific aortic valve disease-on-a-chip platform

TyG × Waist Circumference Composite Indicator and Cardiovascular Disease Risk in Older Adults Across Multiple Regions: A Cross-Sectional Study

Genetic susceptibility to gestational diabetes and its mild modification by bisphenol A and thyroid-stimulating hormone: Findings from a South Chinese pregnancy cohort

Meat processing wastewater; the use of Lemna minor L. to convert an environmental burden into a new resource

Multilevel factors affecting mental health literacy among older adults: a qualitative study based on social ecological model

Dose Response Test of Patient-derived Cancer Organoids to Irradiation

3D-Printed PEEK versus Conventional Free Fibula Flap for Jaw Reconstruction: A Comparative Clinical Study

Remimazolam used for sedation during spinal anesthesia puncture provides faster sedation effect and increase recovery rate compared to midazolam: a randomized controlled trial

Risk Stratification and Survival Prediction in Heart Failure: From Grades to Scores