Drug Holidays | List of Frontiers open access articles

Original Research

Published on 14 Mar 2017

Addressing Adherence Using Genotype-Specific PBPK Modeling—Impact of Drug Holidays on Tamoxifen and Endoxifen Plasma Levels

in Experimental Pharmacology and Drug Discovery

Kristin J. R. Dickschen
Stefan Willmann
Georg Hempel
Michael Block

Frontiers in Pharmacology

doi 10.3389/fphar.2017.00067

4,346 views
5 citations

Original Research

Published on 11 Oct 2023

Planned drug holidays during treatment with lenvatinib for radioiodine-refractory differentiated thyroid cancer: a retrospective study

in Head and Neck Cancer

Chihiro Matsuyama
Tomohiro Enokida
Yuri Ueda
Shinya Suzuki
Takao Fujisawa
Kazue Ito
Susumu Okano
Makoto Tahara

Frontiers in Oncology

doi 10.3389/fonc.2023.1139659

6,192 views
20 citations

Review

Published on 20 Nov 2019

Introducing Patterns of Variability for Overcoming Compensatory Adaptation of the Immune System to Immunomodulatory Agents: A Novel Method for Improving Clinical Response to Anti-TNF Therapies

in Autoimmune and Autoinflammatory Disorders

Tawfik Khoury
Yaron Ilan

Frontiers in Immunology

doi 10.3389/fimmu.2019.02726

7,414 views
75 citations

Original Research

Published on 17 Jun 2022

Assessment of Strategies for Safe Drug Discontinuation and Transition of Denosumab Treatment in PMO—Insights From a Mechanistic PK/PD Model of Bone Turnover

in Biomechanics

Javier Martínez-Reina
José Luis Calvo-Gallego
Madge Martin
Peter Pivonka

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.886579

4,537 views
15 citations

Original Research

Published on 24 Nov 2025

Impact of MEK inhibition on T-cell infiltration and function after radiotherapy in KRAS-mutant lung cancer

in Cancer Immunity and Immunotherapy

Yawen Zheng
Chen Su
Jiachao Pan
Yufeng Wang
Mengmeng Zhao
Mingyan Zhang
Peng Yan
Ning Liu
Meili Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1663502

2,031 views

Original Research

Published on 26 Sep 2022

Skeletal outcomes of patients with osteogenesis imperfecta during drug holiday of bisphosphonates: a real-world study

in Bone Research

Yongze Zhang
Jing Hu
Xiaoyun Lin
Lei Sun
Sunjie Yan
Qian Zhang
Yan Jiang
Ou Wang
Weibo Xia
Xiaoping Xing

Frontiers in Endocrinology

doi 10.3389/fendo.2022.901925

6,096 views
3 citations

Original Research

Published on 30 Sep 2016

Patterns of Non-adherence to Supplementation with Calcium and Vitamin D in Persistent Postmenopausal Women Are Similar at Start and 1 Year Later: A Qualitative Longitudinal Study

in Drugs Outcomes Research and Policies

Tereza Touskova
Magda Vytrisalova
Vladimir Palicka
Tereza Hendrychova
Yang-Ti Chen
Leos Fuksa

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00339

4,870 views
10 citations

Original Research

Published on 26 Oct 2022

Translation suppression underlies the restrained COVID-19 mRNA vaccine response in the high-risk immunocompromised group

in Vaccines and Molecular Therapeutics

Kangsan Kim
Madhusudhanan Narasimhan
Lenin Mahimainathan
Ray Zhang
Ellen Araj
Elizabeth Kim
William Tharpe
Benjamin M. Greenberg
David E. Greenberg
Quan-Zhen Li

Frontiers in Immunology

doi 10.3389/fimmu.2022.1020165

7,308 views

Articles

Addressing Adherence Using Genotype-Specific PBPK Modeling—Impact of Drug Holidays on Tamoxifen and Endoxifen Plasma Levels

Planned drug holidays during treatment with lenvatinib for radioiodine-refractory differentiated thyroid cancer: a retrospective study

Introducing Patterns of Variability for Overcoming Compensatory Adaptation of the Immune System to Immunomodulatory Agents: A Novel Method for Improving Clinical Response to Anti-TNF Therapies

Assessment of Strategies for Safe Drug Discontinuation and Transition of Denosumab Treatment in PMO—Insights From a Mechanistic PK/PD Model of Bone Turnover

Impact of MEK inhibition on T-cell infiltration and function after radiotherapy in KRAS-mutant lung cancer

Skeletal outcomes of patients with osteogenesis imperfecta during drug holiday of bisphosphonates: a real-world study

Patterns of Non-adherence to Supplementation with Calcium and Vitamin D in Persistent Postmenopausal Women Are Similar at Start and 1 Year Later: A Qualitative Longitudinal Study

Translation suppression underlies the restrained COVID-19 mRNA vaccine response in the high-risk immunocompromised group