Early Ra | List of Frontiers open access articles

Original Research

Published on 08 Apr 2024

Abatacept increases T cell exhaustion in early RA individuals who carry HLA risk alleles

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Sarah Alice Long
Virginia S. Muir
Britta E. Jones
Valerie Z. Wall
Alyssa Ylescupidez
Anne M. Hocking
Stephan Pribitzer
Jerill Thorpe
Bryce Fuchs
Alice E. Wiedeman

Frontiers in Immunology

doi 10.3389/fimmu.2024.1383110

7,022 views
8 citations

Original Research

Published on 23 Apr 2025

Alterations in skeletal muscle health and biomechanical properties in patients with early rheumatoid arthritis: an exploratory cross-sectional study

in Striated Muscle Physiology

Brian J. Andonian
Hailee Patel
Mingzhi Xu
Alyssa M. Sudnick
Johanna L. Johnson
William E. Kraus
George A. Truskey
Kim M. Huffman

Frontiers in Physiology

doi 10.3389/fphys.2025.1575689

2,887 views

Original Research

Published on 05 May 2020

CD28− Cells Are Increased in Early Rheumatoid Arthritis and Are Linked With Cytomegalovirus Status

in Rheumatology

Charlotte Thompson
Ruth Davies
Anwen Williams
Gareth Jones
Ernest H. S. Choy

Frontiers in Medicine

doi 10.3389/fmed.2020.00129

4,384 views
7 citations

Original Research

Published on 15 Nov 2021

A Serum Biomarker Panel of exomiR-451a, exomiR-25-3p and Soluble TWEAK for Early Diagnosis of Rheumatoid Arthritis

in Inflammation

Samantha Rodríguez-Muguruza
Antonio Altuna-Coy
Sonia Castro-Oreiro
Maria José Poveda-Elices
Ramon Fontova-Garrofé
Matilde R. Chacón

Frontiers in Immunology

doi 10.3389/fimmu.2021.790880

6,506 views
37 citations

Original Research

Published on 12 Feb 2026

Diagnostic performance of serum 14-3-3η protein versus conventional serological markers in early rheumatoid arthritis

in Inflammation

Tiantian Liu
Wenbin Guo

Frontiers in Immunology

doi 10.3389/fimmu.2026.1746239

332 views

Original Research

Published on 23 Nov 2022

Muscle mass loss is associated with physical dysfunction in patients with early rheumatoid arthritis

in Clinical Nutrition

Jie Pan
Yao-Wei Zou
Ying-Ying Zhu
Jian-Zi Lin
Tao Wu
Ze-Hong Yang
Xue-Pei Zhang
Qian Zhang
Hu-Wei Zheng
Xiao-Ling He

Frontiers in Nutrition

doi 10.3389/fnut.2022.1007184

3,756 views
16 citations

Original Research

Published on 12 Feb 2025

Development of machine learning models for predicting non-remission in early RA highlights the robust predictive importance of the RAID score-evidence from the ARCTIC study

in Precision Medicine

Gaoyang Li
Shrikant S. Kolan
Franco Grimolizzi
Joseph Sexton
Giulia Malachin
Guro Goll
Tore K. Kvien
Nina Paulshus Sundlisæter
Manuela Zucknick
Siri Lillegraven

Frontiers in Medicine

doi 10.3389/fmed.2025.1526708

2,900 views
2 citations

Original Research

Published on 05 Nov 2021

The Macrophage Reprogramming Ability of Antifolates Reveals Soluble CD14 as a Potential Biomarker for Methotrexate Response in Rheumatoid Arthritis

in Molecular Innate Immunity

Sara Fuentelsaz-Romero
Celia Barrio-Alonso
Raquel García Campos
Mónica Torres Torresano
Ittai B. Muller
Ana Triguero-Martínez
Laura Nuño
Alejandro Villalba
Rosario García-Vicuña
Gerrit Jansen

Frontiers in Immunology

doi 10.3389/fimmu.2021.776879

7,026 views
18 citations

Original Research

Published on 03 Jul 2019

IL-6 Mediated Transcriptional Programming of Naïve CD4+ T Cells in Early Rheumatoid Arthritis Drives Dysregulated Effector Function

in Cytokines and Soluble Mediators in Immunity

Laura A. Ridgley
Amy E. Anderson
Nicola J. Maney
Najib Naamane
Andrew J. Skelton
Catherine A. Lawson
Paul Emery
John D. Isaacs
Ruaidhrí J. Carmody
Arthur G. Pratt

Frontiers in Immunology

doi 10.3389/fimmu.2019.01535

14,856 views
27 citations

Original Research

Published on 06 Oct 2021

Identification of Diagnostic Signatures and Immune Cell Infiltration Characteristics in Rheumatoid Arthritis by Integrating Bioinformatic Analysis and Machine-Learning Strategies

in Autoimmune and Autoinflammatory Disorders

Rongguo Yu
Jiayu Zhang
Youguang Zhuo
Xu Hong
Jie Ye
Susu Tang
Yiyuan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2021.724934

15,692 views
58 citations

Original Research

Published on 07 Oct 2021

Anti-Carbamylated Fibrinogen Antibodies Might Be Associated With a Specific Rheumatoid Phenotype and Include a Subset Recognizing In Vivo Epitopes of Its γ Chain One of Which Is Not Cross Reactive With Anti-Citrullinated Protein Antibodies

in Autoimmune and Autoinflammatory Disorders

Pauline Brevet
Claire Lattard
Clément Guillou
Pascal Rottenberg
Patrice Fardellone
Xavier Le-Loët
Thierry Lequerré
Pascal Cosette
Olivier Boyer
Manuel Fréret

Frontiers in Immunology

doi 10.3389/fimmu.2021.733511

4,496 views
15 citations

Brief Research Report

Published on 14 Jul 2020

Persistence of Mast Cell-Positive Synovitis in Early Rheumatoid Arthritis Following Treatment With Conventional Synthetic Disease Modifying Anti-Rheumatic Drugs

in Inflammation Pharmacology

Felice Rivellese
Francesca W. Rossi
Giovanni Giorli
Filomena Napolitano
Amato de Paulis
Costantino Pitzalis

Frontiers in Pharmacology

doi 10.3389/fphar.2020.01051

5,450 views
4 citations

Original Research

Published on 20 Aug 2021

A Cross-Sectional and Longitudinal Study to Define Alarmins and A-SAA Variants as Companion Markers in Early Rheumatoid Arthritis

in Autoimmune and Autoinflammatory Disorders

Federica Ciregia
Gwenaël Nys
Gaël Cobraiville
Valérie Badot
Silvana Di Romana
Paschalis Sidiras
Tatiana Sokolova
Patrick Durez
Marianne Fillet
Michel G. Malaise

Frontiers in Immunology

doi 10.3389/fimmu.2021.638814

4,384 views
6 citations

Original Research

Published on 25 Jun 2021

Circulating and Synovial Pentraxin-3 (PTX3) Expression Levels Correlate With Rheumatoid Arthritis Severity and Tissue Infiltration Independently of Conventional Treatments Response

in Autoimmune and Autoinflammatory Disorders

Marie-Astrid Boutet
Alessandra Nerviani
Gloria Lliso-Ribera
Roberto Leone
Marina Sironi
Rebecca Hands
Felice Rivellese
Annalisa Del Prete
Katriona Goldmann
Myles J. Lewis

Frontiers in Immunology

doi 10.3389/fimmu.2021.686795

7,115 views
19 citations

Original Research

Published on 13 Aug 2021

Identifying Immune Cell Infiltration and Effective Diagnostic Biomarkers in Rheumatoid Arthritis by Bioinformatics Analysis

in Autoimmune and Autoinflammatory Disorders

Sheng Zhou
Hongcheng Lu
Min Xiong

Frontiers in Immunology

doi 10.3389/fimmu.2021.726747

30,579 views
120 citations

Original Research

Published on 11 Oct 2018

Profiling of B-Cell Factors and Their Decoy Receptors in Rheumatoid Arthritis: Association With Clinical Features and Treatment Outcomes

in B Cell Biology

Javier Rodríguez-Carrio
Mercedes Alperi-López
Patricia López
Francisco J. Ballina-García
Ana Suárez

Frontiers in Immunology

doi 10.3389/fimmu.2018.02351

5,936 views
11 citations

Articles

Abatacept increases T cell exhaustion in early RA individuals who carry HLA risk alleles

Alterations in skeletal muscle health and biomechanical properties in patients with early rheumatoid arthritis: an exploratory cross-sectional study

CD28− Cells Are Increased in Early Rheumatoid Arthritis and Are Linked With Cytomegalovirus Status

A Serum Biomarker Panel of exomiR-451a, exomiR-25-3p and Soluble TWEAK for Early Diagnosis of Rheumatoid Arthritis

Diagnostic performance of serum 14-3-3η protein versus conventional serological markers in early rheumatoid arthritis

Muscle mass loss is associated with physical dysfunction in patients with early rheumatoid arthritis

Development of machine learning models for predicting non-remission in early RA highlights the robust predictive importance of the RAID score-evidence from the ARCTIC study

The Macrophage Reprogramming Ability of Antifolates Reveals Soluble CD14 as a Potential Biomarker for Methotrexate Response in Rheumatoid Arthritis

IL-6 Mediated Transcriptional Programming of Naïve CD4+ T Cells in Early Rheumatoid Arthritis Drives Dysregulated Effector Function

Identification of Diagnostic Signatures and Immune Cell Infiltration Characteristics in Rheumatoid Arthritis by Integrating Bioinformatic Analysis and Machine-Learning Strategies

Anti-Carbamylated Fibrinogen Antibodies Might Be Associated With a Specific Rheumatoid Phenotype and Include a Subset Recognizing In Vivo Epitopes of Its γ Chain One of Which Is Not Cross Reactive With Anti-Citrullinated Protein Antibodies

Persistence of Mast Cell-Positive Synovitis in Early Rheumatoid Arthritis Following Treatment With Conventional Synthetic Disease Modifying Anti-Rheumatic Drugs

A Cross-Sectional and Longitudinal Study to Define Alarmins and A-SAA Variants as Companion Markers in Early Rheumatoid Arthritis

Circulating and Synovial Pentraxin-3 (PTX3) Expression Levels Correlate With Rheumatoid Arthritis Severity and Tissue Infiltration Independently of Conventional Treatments Response

Identifying Immune Cell Infiltration and Effective Diagnostic Biomarkers in Rheumatoid Arthritis by Bioinformatics Analysis

Profiling of B-Cell Factors and Their Decoy Receptors in Rheumatoid Arthritis: Association With Clinical Features and Treatment Outcomes