Environmental Enrichment Ee | List of Frontiers open access articles

Original Research

Published on 05 May 2021

Environmental Enrichment Induces Epigenomic and Genome Organization Changes Relevant for Cognition

in Molecular Signalling and Pathways

Sergio Espeso-Gil
Aliaksei Z. Holik
Sarah Bonnin
Shalu Jhanwar
Sandhya Chandrasekaran
Roger Pique-Regi
Júlia Albaigès-Ràfols
Michael Maher
Jon Permanyer
Manuel Irimia

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.664912

17,006 views
30 citations

Original Research

Published on 29 Aug 2019

Effects of Environmental Enrichment in Maternally Separated Rats: Age and Sex-Specific Outcomes

in Emotion Regulation and Processing

Raura Doreste-Mendez
Efraín J. Ríos-Ruiz
Leslie L. Rivera-López
Alfredo Gutierrez
Annelyn Torres-Reveron

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2019.00198

6,819 views
19 citations

Original Research

Published on 20 Sep 2022

Bifidobacterium breve intervention combined with environmental enrichment alleviates cognitive impairment by regulating the gut microbiota and microbial metabolites in Alzheimer’s disease mice

in Microbial Immunology

Guangsu Zhu
Min Guo
Jianxin Zhao
Hao Zhang
Gang Wang
Wei Chen

Frontiers in Immunology

doi 10.3389/fimmu.2022.1013664

7,975 views
26 citations

Original Research

Published on 25 Feb 2020

Environmental Enrichment Rescues Visually-Mediated Behavior in Ten-m3 Knockout Mice During an Early Critical Period

in Motivation and Reward

James Blok
Dylan A. Black
Justin Petersen
Atomu Sawatari
Catherine A. Leamey

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2020.00022

4,126 views
6 citations

Mini Review

Published on 21 Mar 2025

Environmental enrichment for neuropathic pain via modulation of neuroinflammation

in Pain Mechanisms and Modulators

Jian-Dong Zhang
Zi-An Zhong
Wen-Yuan Xing

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1547647

3,000 views
1 citation

Review

Published on 29 Sep 2022

The effects and mechanism of environmental enrichment on MK-801 induced cognitive impairment in rodents with schizophrenia

in Cellular Neurophysiology

Jinwei Xu
Yaohao Li
Biqing Tian
Haiying Liu
Shengxi Wu
Wenting Wang

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2022.1024649

6,647 views
13 citations

Review

Published on 12 Nov 2018

Pre-reproductive Parental Enriching Experiences Influence Progeny’s Developmental Trajectories

in Individual and Social Behaviors

Debora Cutuli
Erica Berretta
Daniela Laricchiuta
Paola Caporali
Francesca Gelfo
Laura Petrosini

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2018.00254

6,122 views
14 citations

Brief Research Report

Published on 26 Sep 2023

Enlarged housing space and increased spatial complexity enhance hippocampal neurogenesis but do not increase physical activity in mice

in Exercise Physiology

Daisuke Funabashi
Ryuki Tsuchida
Takashi Matsui
Ichiro Kita
Takeshi Nishijima

Frontiers in Sports and Active Living

doi 10.3389/fspor.2023.1203260

2,703 views
8 citations

Review

Published on 10 Aug 2023

Neuroprotection in metabolic syndrome by environmental enrichment. A lifespan perspective

in Neurodegeneration

Tamara Kobiec
Claudia Mardaraz
Nicolás Toro-Urrego
Rodolfo Kölliker-Frers
Francisco Capani
Matilde Otero-Losada

Frontiers in Neuroscience

doi 10.3389/fnins.2023.1214468

4,587 views
4 citations

Review

Published on 29 Nov 2018

Environmental Enrichment Modulates Drug Addiction and Binge-Like Consumption of Highly Rewarding Substances: A Role for Anxiety and Compulsivity Brain Systems?

in Motivation and Reward

Elisa Rodríguez-Ortega
Inmaculada Cubero

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2018.00295

7,666 views
10 citations

Original Research

Published on 04 Mar 2015

Impairments in cognition and neural precursor cell proliferation in mice expressing constitutively active glycogen synthase kinase-3

in Individual and Social Behaviors

Marta Pardo
Margaret K. King
Emma Perez-Costas
Miguel Melendez-Ferro
Ana Martinez
Eleonore Beurel
Richard S. Jope

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2015.00055

6,149 views
18 citations

Review

Published on 02 Sep 2014

Environmental enrichment and the sensory brain: the role of enrichment in remediating brain injury

Dasuni S. Alwis
Ramesh Rajan

Frontiers in Systems Neuroscience

doi 10.3389/fnsys.2014.00156

24,265 views
119 citations

Original Research

Published on 17 Oct 2025

Cognitive enrichment improves spatial memory and alters hippocampal synaptic connectivity in a mouse model for early-life stress

in Cellular Neurophysiology

Justin L. Shobe
Elham Ghanbarian
Robert Bain
Rajat Saxena
Meenakshi Chandrasekaran
Bruce L. McNaughton

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1646883

2,582 views

Original Research

Published on 12 Mar 2015

Pre-reproductive maternal enrichment influences rat maternal care and offspring developmental trajectories: behavioral performances and neuroplasticity correlates

in Individual and Social Behaviors

Debora Cutuli
Paola Caporali
Francesca Gelfo
Francesco Angelucci
Daniela Laricchiuta
Francesca Foti
Paola De Bartolo
Elisa Bisicchia
Marco Molinari
Stefano Farioli Vecchioli

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2015.00066

12,087 views
41 citations

Original Research

Published on 18 Mar 2020

Duration of Environmental Enrichment Determines Astrocyte Number and Cervical Lymph Node T Lymphocyte Proportions but Not the Microglial Number in Middle-Aged C57BL/6 Mice

in Non-Neuronal Cells

Gaurav Singhal
Julie Morgan
Magdalene C. Jawahar
Frances Corrigan
Emily J. Jaehne
Catherine Toben
Jim Manavis
Anthony J. Hannan
Bernhard T. Baune

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2020.00057

5,506 views
14 citations

Original Research

Published on 09 Apr 2025

Effect of different levels of environmental enrichment on the welfare of guppy (Poecilia reticulata)

in Fish Experimental Biology

Isabella Manenti
Benedetto Sicuro
Elisabetta Macchi
Patrizia Ponzio
Riccardo Crosetto
Sharon Cavallari
Martina Tarantola
Cecilia Mugnai

Frontiers in Fish Science

doi 10.3389/frish.2025.1581493

3,258 views
1 citation

Articles

Environmental Enrichment Induces Epigenomic and Genome Organization Changes Relevant for Cognition

Effects of Environmental Enrichment in Maternally Separated Rats: Age and Sex-Specific Outcomes

Bifidobacterium breve intervention combined with environmental enrichment alleviates cognitive impairment by regulating the gut microbiota and microbial metabolites in Alzheimer’s disease mice

Environmental Enrichment Rescues Visually-Mediated Behavior in Ten-m3 Knockout Mice During an Early Critical Period

Environmental enrichment for neuropathic pain via modulation of neuroinflammation

The effects and mechanism of environmental enrichment on MK-801 induced cognitive impairment in rodents with schizophrenia

Pre-reproductive Parental Enriching Experiences Influence Progeny’s Developmental Trajectories

Enlarged housing space and increased spatial complexity enhance hippocampal neurogenesis but do not increase physical activity in mice

Neuroprotection in metabolic syndrome by environmental enrichment. A lifespan perspective

Environmental Enrichment Modulates Drug Addiction and Binge-Like Consumption of Highly Rewarding Substances: A Role for Anxiety and Compulsivity Brain Systems?

Impairments in cognition and neural precursor cell proliferation in mice expressing constitutively active glycogen synthase kinase-3

Environmental enrichment and the sensory brain: the role of enrichment in remediating brain injury

Cognitive enrichment improves spatial memory and alters hippocampal synaptic connectivity in a mouse model for early-life stress

Pre-reproductive maternal enrichment influences rat maternal care and offspring developmental trajectories: behavioral performances and neuroplasticity correlates

Duration of Environmental Enrichment Determines Astrocyte Number and Cervical Lymph Node T Lymphocyte Proportions but Not the Microglial Number in Middle-Aged C57BL/6 Mice

Effect of different levels of environmental enrichment on the welfare of guppy (Poecilia reticulata)