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5 articles related to "Fg 4592"

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Articles

Original Research

Published on 15 Aug 2023

FG-4592 relieves diabetic kidney disease severity by influencing metabolic profiles via gut microbiota reconstruction in both human and mouse models

in Renal Physiology and Pathophysiology

Yumin Jiang
Wen Cui
Yiding Zhang
Ting Wang
Xuejun Zheng
Huangmin Li
Jin Shang

Frontiers in Physiology

doi 10.3389/fphys.2023.1195441

4,618 views
4 citations

Original Research

Published on 25 Feb 2022

Roxadustat (FG-4592) Facilitates Recovery From Renal Damage by Ameliorating Mitochondrial Dysfunction Induced by Folic Acid

in Renal Pharmacology

Xue Li
Bo Jiang
Yu Zou
Jie Zhang
Yuan-Yuan Fu
Xiao-Yue Zhai

Frontiers in Pharmacology

doi 10.3389/fphar.2021.788977

7,597 views
14 citations

Original Research

Published on 05 Aug 2020

Antianemia Drug Roxadustat (FG-4592) Protects Against Doxorubicin-Induced Cardiotoxicity by Targeting Antiapoptotic and Antioxidative Pathways

in Cardiovascular and Smooth Muscle Pharmacology

Guangfeng Long
Hongbing Chen
Mengying Wu
Yuanyuan Li
Ling Gao
Songming Huang
Yue Zhang
Zhanjun Jia
Weiwei Xia

Frontiers in Pharmacology

doi 10.3389/fphar.2020.01191

12,442 views
36 citations

Original Research

Published on 27 Apr 2018

Therapeutic Potential of a Prolyl Hydroxylase Inhibitor FG-4592 for Parkinson’s Diseases in Vitro and in Vivo: Regulation of Redox Biology and Mitochondrial Function

in Neuroinflammation and Neuropathy

Xuan Li
Xin-Xin Cui
Ya-Jing Chen
Ting-Ting Wu
Huaxi Xu
Huiyong Yin
Yun-Cheng Wu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00121

15,576 views
72 citations

Original Research

Published on 03 Nov 2022

Dietary choline, via gut microbe- generated trimethylamine-N- oxide, aggravates chronic kidney disease-induced cardiac dysfunction by inhibiting hypoxia-induced factor 1α

in Renal Physiology and Pathophysiology

Feifei Xie
Xin Zhen
Zhuoliang Liu
Xiaomei Chen
Zhuanhua Liu
Miaomiao Zhou
Zhanmei Zhou
Zheng Hu
Fengxin Zhu
Qiaobing Huang

Frontiers in Physiology

doi 10.3389/fphys.2022.996166

7,265 views
11 citations