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3 articles related to "First Pass Metabolism"

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Articles

Original Research

Published on 28 Sep 2023

A pilot study of cerebral metabolism and serotonin 5-HT2A receptor occupancy in rats treated with the psychedelic tryptamine DMT in conjunction with the MAO inhibitor harmine

in Neuropharmacology

Klemens Egger
Frederik Gudmundsen
Naja Støckel Jessen
Christina Baun
Sandra N. Poetzsch
Vladimir Shalgunov
Matthias M. Herth
Boris B. Quednow
Chantal Martin-Soelch
Dario Dornbierer

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1140656

10,203 views
13 citations

Original Research

Published on 08 Apr 2025

Pharmacokinetics of cannabidiol, (-)-trans-Δ9-tetrahydrocannabinol, and their oxidative metabolites after intravenous and oral administration of a cannabidiol-dominant full-spectrum hemp product to beagle dogs

in Veterinary Pharmacology and Toxicology

Susanna E. Kitts-Morgan
Richard A. Sams
William W. Muir

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1556975

3,854 views
5 citations

Editorial

Published on 20 May 2021

Editorial: Pharmacokinetic Evaluation and Modeling of Clinically Significant Drug Metabolites

in Drug Metabolism and Transport

Constantin Mircioiu
Valentina Anuta
Momir Mikov
Adrian Nicolescu
Victor A. Voicu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.693922

2,951 views