Functional Optimization | List of Frontiers open access articles

Perspective

Published on 06 Mar 2026

Mitochondrial stress as a conceptual interface between bacterial infection and post-infectious metabolic disease

in Adaptive & Innate Immunity in Infection

Nicolás Plaza
Diliana Pérez-Reytor
Gino Corsini
Katherine García
Ítalo M. Urrutia

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2026.1795935

Opinion

Published on 06 Mar 2026

Reevaluating sport tourism advancement in emerging destinations: a community-focused framework for sustainable value generation

in Sport, Leisure, Tourism, and Events

Qodirov Azizjon Anvarovich
Urakova Dilfuza Bakhriddinovna

Frontiers in Sports and Active Living

doi 10.3389/fspor.2026.1795290

Editorial

Published on 06 Mar 2026

Editorial: Safety and efficacy of CRISPR/Cas-based genome editing tools: applications and considerations in cell and gene therapy

in Cancer Immunity and Immunotherapy

Karl Petri
Samuele Ferrari
Beatrice Claudia Cianciotti

Frontiers in Immunology

doi 10.3389/fimmu.2026.1809809

Correction

Published on 06 Mar 2026

Correction: Neurodegeneration of the cornea and retina in patients with type 1 diabetes without clinical evidence of diabetic retinopathy

in Clinical Diabetes

Josie Carmichael
Hassan Fadavi
Mitra Tavakoli

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1809367

Editorial

Published on 06 Mar 2026

Editorial: Effects of tobacco use on oral health

in Oral Epidemiology

Praveen Jodalli
Mamata Hebbal

Frontiers in Oral Health

doi 10.3389/froh.2026.1803555

359 views

Systematic Review

Published on 06 Mar 2026

Performance of artificial intelligence models designed as adjuncts for determining working length and apical landmark assessment in endodontic procedures: a systematic review

in Dental Materials

Sanjeev B. Khanagar
Majed Alharthi
Adel Asery
Muhammad Alalweet
Abdullah Aldobiyan
Meshal Alhayf
Ahmed Binobaid

Frontiers in Dental Medicine

doi 10.3389/fdmed.2026.1783828

Original Research

Published on 06 Mar 2026

Sperm whale hotspots off western Ireland and the importance of dynamic variables as shown by a multiscale Bayesian additive regression trees workflow

in Marine Megafauna

Cynthia Barile
Simon Berrow
Jonathan Gordon
Rossa Meade
Morgane Pommier
Joanne O’Brien

Frontiers in Marine Science

doi 10.3389/fmars.2026.1767540

326 views

Original Research

Published on 06 Mar 2026

Exploring the influence of AI self-study rooms on K–12 learners’ motivation, self-regulation, enjoyment, and engagement

in Educational Psychology

Wei Li
Ya Xu
Le Yao
Yantong Liu

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1768389

494 views

Original Research

Published on 06 Mar 2026

Decision-making for pediatric vaccination scheduling under multiple constraints: a case study from China✰

in Public Health Policy

Xiaochen Ma
Qiang Huang
Shanshan Chai
Mingxia Zhang

Frontiers in Public Health

doi 10.3389/fpubh.2026.1768367

142 views

Systematic Review

Published on 06 Mar 2026

Osteocytes orchestrate browning: emerging signals in bone-fat crosstalk: a systematic review

in Bone Research

Houmam Anees
Vahid Jahed
Zahra Sabouri
Reem Jamous
Cristian Pablo Pennisi
Christian Heiss
Thaqif El Khassawna

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1766959

222 views

Original Research

Published on 06 Mar 2026

Mental health burden and service barriers among medical and health sciences students: prevalence and determinants from a cross-sectional analysis

in Health Psychology

Shaimaa M. Hassan
Najeeb M. Alqahtani
Salihah M. Alshahrani
Aser M. Abuelnasr
Abdulkhalig A. Alhefzy
Khaled W. Al Assiri
Bandar W. Al Assiri
Omar S. Alharthi
Muhannad M. Alharbi

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1765447

149 views

Original Research

Published on 06 Mar 2026

Integrating pharmacovigilance signals with real-world validation: a study on neurological events associated with PCSK9 inhibitors

in Translational Medicine

Bing Zhu
Qiqi Shao
Jun Cui
Zhenyan Fu
Yitong Ma

Frontiers in Medicine

doi 10.3389/fmed.2026.1765715

Case Report

Published on 06 Mar 2026

Next generation sequencing guided treatment of ALK tyrosine kinase inhibitor induced long survival in lung squamous cell carcinoma harboring ROS1 gene fusions: a case report and literature review

in Precision Medicine

Mei Liu
Fenge Li
Ning Mu
Ning Kang
Shengnan Wu
Yue Xu
Xinyi Wang
Huan Lü
Chunhua Ma

Frontiers in Medicine

doi 10.3389/fmed.2026.1771353

122 views

Original Research

Published on 06 Mar 2026

Development and efficacy evaluation of a competency-based training program for pediatric operating room nurses

in Healthcare Professions Education

Qingqing Du
Zhen Wang
Mengfan Xia
Jing Cao
Yingmin Liu
Ziwei Jin
Xia Yang

Frontiers in Medicine

doi 10.3389/fmed.2026.1769565

210 views

Review

Published on 06 Mar 2026

Genetic and epigenetic determinants of vitamin D metabolism: nutrigenomic insights for precision nutrition

in Nutrigenomics

Fatima Qahtan
Salma Abu-Qiyas
Dimitrios Papandreou

Frontiers in Nutrition

doi 10.3389/fnut.2026.1772849

197 views

Case Report

Published on 06 Mar 2026

Undifferentiated embryonal sarcoma of the liver in an 11-year-old boy: a case report and clinical insights

in Surgical Oncology

Zhiru Liang
Weihong Chen
Weihong Duan
Chaoyue Song
Jianjia Xiao
Delei Yu
Yu Xie

Frontiers in Surgery

doi 10.3389/fsurg.2026.1772085

Articles

Mitochondrial stress as a conceptual interface between bacterial infection and post-infectious metabolic disease

Reevaluating sport tourism advancement in emerging destinations: a community-focused framework for sustainable value generation

Editorial: Safety and efficacy of CRISPR/Cas-based genome editing tools: applications and considerations in cell and gene therapy

Correction: Neurodegeneration of the cornea and retina in patients with type 1 diabetes without clinical evidence of diabetic retinopathy

Editorial: Effects of tobacco use on oral health

Performance of artificial intelligence models designed as adjuncts for determining working length and apical landmark assessment in endodontic procedures: a systematic review

Sperm whale hotspots off western Ireland and the importance of dynamic variables as shown by a multiscale Bayesian additive regression trees workflow

Exploring the influence of AI self-study rooms on K–12 learners’ motivation, self-regulation, enjoyment, and engagement

Decision-making for pediatric vaccination scheduling under multiple constraints: a case study from China✰

Osteocytes orchestrate browning: emerging signals in bone-fat crosstalk: a systematic review

Mental health burden and service barriers among medical and health sciences students: prevalence and determinants from a cross-sectional analysis

Integrating pharmacovigilance signals with real-world validation: a study on neurological events associated with PCSK9 inhibitors

Next generation sequencing guided treatment of ALK tyrosine kinase inhibitor induced long survival in lung squamous cell carcinoma harboring ROS1 gene fusions: a case report and literature review

Development and efficacy evaluation of a competency-based training program for pediatric operating room nurses

Genetic and epigenetic determinants of vitamin D metabolism: nutrigenomic insights for precision nutrition

Undifferentiated embryonal sarcoma of the liver in an 11-year-old boy: a case report and clinical insights