Functional Pharmacology | List of Frontiers open access articles

Brief Research Report

Published on 17 May 2021

The Drosophila melanogaster Levodopa-Induced Depression Model Exhibits Negative Geotaxis Deficits and Differential Gene Expression in Males and Females

in Neurogenomics

Thiago C. Moulin
Federico Ferro
Angela Hoyer
Pierre Cheung
Michael J. Williams
Helgi B. Schiöth

Frontiers in Neuroscience

doi 10.3389/fnins.2021.653470

14,754 views
17 citations

Original Research

Published on 15 May 2024

Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts

in Adolescent and Young Adult Psychiatry

Aleksandr V. Sokolov
Muataz S. Lafta
Didi O. T. Nordberg
Jörgen Jonsson
Helgi B. Schiöth

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1372106

4,621 views
3 citations

Original Research

Published on 04 Aug 2025

Statins regulate kinase signaling by causing changes in phosphorylation, rather than through changes in gene expression or direct inhibition: evidence in colorectal cancer

in Experimental Pharmacology and Drug Discovery

Francisco Alejandro Lagunas-Rangel
Jörgen Jonsson
Ludmila Jackevica
Robert Fredriksson
Maija Dambrova
Helgi B. Schiöth

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1653702

3,090 views
4 citations

Original Research

Published on 24 May 2023

Efficacy of combination therapy with GABA, a DPP-4i and a PPI as an adjunct to insulin therapy in patients with type 1 diabetes

in Clinical Diabetes

Alexander Rabinovitch
Daniil Koshelev
Francisco Alejandro Lagunas-Rangel
Liudmila Kosheleva
Tali Gavra
Helgi B. Schiöth
Shmuel Levit

Frontiers in Endocrinology

doi 10.3389/fendo.2023.1171886

24,121 views
15 citations

Original Research

Published on 21 Oct 2022

Triple drug therapy with GABA, sitagliptin, and omeprazole prevents type 1 diabetes onset and promotes its reversal in non-obese diabetic mice

in Clinical Diabetes

Francisco Alejandro Lagunas-Rangel
Daniil Koshelev
Andrej Nedorubov
Liudmila Kosheleva
Vladimir Trukhan
Alexander Rabinovitch
Helgi B. Schiöth
Shmuel Levit

Frontiers in Endocrinology

doi 10.3389/fendo.2022.1028114

19,667 views
13 citations

Original Research

Published on 18 Jun 2015

Recurrent seizure-like events are associated with coupled astroglial synchronization

in Cellular Neurophysiology

Orsolya Kékesi
Enikö Ioja
Zsolt Szabó
Julianna Kardos
László Héja

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2015.00215

6,639 views
43 citations

Original Research

Published on 28 Apr 2022

Evidence of a Causal Link Between the Well-Being Spectrum and the Risk of Myocardial Infarction: A Mendelian Randomization Study

in Applied Genetic Epidemiology

Gull Rukh
Shafqat Ahmad
Lars Lind
Helgi Birgir Schiöth

Frontiers in Genetics

doi 10.3389/fgene.2022.842223

5,620 views
7 citations

Review

Published on 21 Feb 2024

Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology

in Neuroendocrine Science

Muataz S. Lafta
Jessica Mwinyi
Oreste Affatato
Gull Rukh
Junhua Dang
Gerhard Andersson
Helgi B. Schiöth

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1340108

15,813 views
32 citations

Review

Published on 15 Aug 2022

Statins and cognition: Modifying factors and possible underlying mechanisms

in Alzheimer's Disease and Related Dementias

Tahereh Jamshidnejad-Tosaramandani
Soheila Kashanian
Mohamed H. Al-Sabri
Daniela Kročianová
Laura E. Clemensson
Mélissa Gentreau
Helgi B. Schiöth

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.968039

66,856 views
50 citations

Systematic Review

Published on 16 Jun 2020

The Synaptic Scaling Literature: A Systematic Review of Methodologies and Quality of Reporting

in Cellular Neurophysiology

Thiago C. Moulin
Danielle Rayêe
Michael J. Williams
Helgi B. Schiöth

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2020.00164

10,026 views
25 citations

Systematic Review

Published on 18 Jul 2022

Subliminal Emotional Faces Elicit Predominantly Right-Lateralized Amygdala Activation: A Systematic Meta-Analysis of fMRI Studies

in Perception Science

Amelia D. Dahlén
Aphra Schofield
Helgi B. Schiöth
Samantha J. Brooks

Frontiers in Neuroscience

doi 10.3389/fnins.2022.868366

8,182 views
22 citations

Original Research

Published on 10 May 2019

Connexin 43 Differentially Regulates Epileptiform Activity in Models of Convulsive and Non-convulsive Epilepsies

in Cellular Neurophysiology

Renáta Vincze
Márton Péter
Zsolt Szabó
Julianna Kardos
László Héja
Zsolt Kovács

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2019.00173

5,006 views
27 citations

Original Research

Published on 05 Jan 2026

Lauric acid modulates the cyclooxygenases and nitric oxide pathways and reduces oxidative stress in preventing tracheal hyperresponsiveness in asthmatic Wistar rats

in Respiratory Pharmacology

Indyra Alencar Duarte Figueiredo
Alissa Maria de Oliveira Martins
Alexya Mikelle Teixeira Cavalcanti
Jayne Muniz Fernandes
Ludmila Emilly da Silva Gomes
Gabriel Nunes Machado de Oliveira
Lucas Nóbrega de Oliveira
Isabela Motta Felício
Adriana Maria Fernandes de Oliveira Golzio
Adriano Francisco Alves

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657799

3,433 views

Original Research

Published on 01 Mar 2021

Spontaneous Ca2+ Fluctuations Arise in Thin Astrocytic Processes With Real 3D Geometry

in Non-Neuronal Cells

László Héja
Zsolt Szabó
Márton Péter
Julianna Kardos

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2021.617989

7,270 views
16 citations

Original Research

Published on 01 Mar 2024

Differential change in alcohol consumption during the COVID-19 pandemic: the role of loneliness, socialization, and mental well-being

in Addictive Disorders

Mohamed S. Mohamed
Gull Rukh
Sofia Vadlin
Susanne Olofsdotter
Cecilia Åslund
Helgi B. Schiöth
Kent W. Nilsson

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1236410

3,538 views
2 citations

Original Research

Published on 06 Jan 2022

Critical Role of Astrocytic Polyamine and GABA Metabolism in Epileptogenesis

in Non-Neuronal Cells

Zsolt Kovács
Serguei N. Skatchkov
Rüdiger W. Veh
Zsolt Szabó
Krisztina Németh
Pál T. Szabó
Julianna Kardos
László Héja

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2021.787319

11,135 views
38 citations

Articles

The Drosophila melanogaster Levodopa-Induced Depression Model Exhibits Negative Geotaxis Deficits and Differential Gene Expression in Males and Females

Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts

Statins regulate kinase signaling by causing changes in phosphorylation, rather than through changes in gene expression or direct inhibition: evidence in colorectal cancer

Efficacy of combination therapy with GABA, a DPP-4i and a PPI as an adjunct to insulin therapy in patients with type 1 diabetes

Triple drug therapy with GABA, sitagliptin, and omeprazole prevents type 1 diabetes onset and promotes its reversal in non-obese diabetic mice

Recurrent seizure-like events are associated with coupled astroglial synchronization

Evidence of a Causal Link Between the Well-Being Spectrum and the Risk of Myocardial Infarction: A Mendelian Randomization Study

Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology

Statins and cognition: Modifying factors and possible underlying mechanisms

The Synaptic Scaling Literature: A Systematic Review of Methodologies and Quality of Reporting

Subliminal Emotional Faces Elicit Predominantly Right-Lateralized Amygdala Activation: A Systematic Meta-Analysis of fMRI Studies

Connexin 43 Differentially Regulates Epileptiform Activity in Models of Convulsive and Non-convulsive Epilepsies

Lauric acid modulates the cyclooxygenases and nitric oxide pathways and reduces oxidative stress in preventing tracheal hyperresponsiveness in asthmatic Wistar rats

Spontaneous Ca2+ Fluctuations Arise in Thin Astrocytic Processes With Real 3D Geometry

Differential change in alcohol consumption during the COVID-19 pandemic: the role of loneliness, socialization, and mental well-being

Critical Role of Astrocytic Polyamine and GABA Metabolism in Epileptogenesis