G2m Checkpoint | List of Frontiers open access articles

Original Research

Published on 08 Dec 2022

G2/M checkpoint regulation and apoptosis facilitate the nuclear egress of parvoviral capsids

in Membrane Traffic and Organelle Dynamics

Salla Mattola
Elina Mäntylä
Vesa Aho
Sami Salminen
Simon Leclerc
Mikko Oittinen
Kari Salokas
Jani Järvensivu
Satu Hakanen
Teemu O Ihalainen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.1070599

5,702 views
9 citations

Original Research

Published on 28 May 2021

G2/M Checkpoint Abrogation With Selective Inhibitors Results in Increased Chromatid Breaks and Radiosensitization of 82-6 hTERT and RPE Human Cells

in Radiation and Health

Aggeliki Nikolakopoulou
Aashish Soni
Martha Habibi
Pantelis Karaiskos
Gabriel Pantelias
Georgia I. Terzoudi
George Iliakis

Frontiers in Public Health

doi 10.3389/fpubh.2021.675095

5,173 views
6 citations

Original Research

Published on 08 Sep 2020

AMPK Activity Contributes to G2 Arrest and DNA Damage Decrease via p53/p21 Pathways in Oxidatively Damaged Mouse Zygotes

in Cell Growth and Division

Pei He
Zhiling Li
Feng Xu
Gaizhen Ru
Yue Huang
En Lin
Sanfeng Peng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2020.539485

6,916 views
28 citations

Original Research

Published on 02 Nov 2023

Myt1 overexpression mediates resistance to cell cycle and DNA damage checkpoint kinase inhibitors

in Cell Growth and Division

Sargun Sokhi
Cody W. Lewis
Amirali B. Bukhari
Joanne Hadfield
Edric J. Xiao
Jeremy Fung
Yea Jin Yoon
Wen-Hsin Hsu
Armin M. Gamper
Gordon K. Chan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2023.1270542

6,553 views
9 citations

Review

Published on 17 Feb 2022

Targeting the DNA Damage Response for Cancer Therapy by Inhibiting the Kinase Wee1

in Cancer Molecular Targets and Therapeutics

Amirali B. Bukhari
Gordon K. Chan
Armin M. Gamper

Frontiers in Oncology

doi 10.3389/fonc.2022.828684

15,667 views
55 citations

Review

Published on 06 Oct 2022

DNA damage checkpoint execution and the rules of its disengagement

in Cell Growth and Division

Candice Qiu Xia Yam
Hong Hwa Lim
Uttam Surana

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.1020643

9,572 views
32 citations

Original Research

Published on 13 Jul 2022

Stable CDK12 Knock-Out Ovarian Cancer Cells Do Not Show Increased Sensitivity to Cisplatin and PARP Inhibitor Treatment

in Pharmacology of Anti-Cancer Drugs

Rosaria Chilà
Michela Chiappa
Federica Guffanti
Nicolò Panini
Donatella Conconi
Andrea Rinaldi
Luciano Cascione
Francesco Bertoni
Maddalena Fratelli
Giovanna Damia

Frontiers in Oncology

doi 10.3389/fonc.2022.903536

6,689 views
5 citations

Original Research

Published on 02 Sep 2022

Effect of safranal on the response of cancer cells to topoisomerase I inhibitors: Does sequence matter?

in Pharmacology of Anti-Cancer Drugs

Lama Lozon
Ekram Saleh
Varsha Menon
Wafaa S. Ramadan
Amr Amin
Raafat El-Awady

Frontiers in Pharmacology

doi 10.3389/fphar.2022.938471

4,163 views
26 citations

Original Research

Published on 25 Mar 2025

Milciclib-mediated CDK2 inhibition to boost radiotherapy sensitivity in colorectal cancer

in Pharmacology of Anti-Cancer Drugs

Junjie Ma
Shanshan Wu
Xinxin Yang
Shuying Shen
Yiqian Zhu
Ruoqi Wang
Wei Xu
Yue Li
Haixin Zhu
Youyou Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1557925

3,168 views
1 citation

Original Research

Published on 02 May 2024

KDM7A-DT induces genotoxic stress, tumorigenesis, and progression of p53 missense mutation-associated invasive breast cancer

in Molecular and Cellular Oncology

Antonis Giannakakis
Margaritis Tsifintaris
Vasileios Gouzouasis
Ghim Siong Ow
Mei Yee Aau
Csaba Papp
Anna V. Ivshina
Vladimir A. Kuznetsov

Frontiers in Oncology

doi 10.3389/fonc.2024.1227151

4,276 views
5 citations

Original Research

Published on 01 Apr 2021

Capilliposide C from Lysimachia capillipes Restores Radiosensitivity in Ionizing Radiation-Resistant Lung Cancer Cells Through Regulation of ERRFI1/EGFR/STAT3 Signaling Pathway

in Pharmacology of Anti-Cancer Drugs

Kan Wu
Xueqin Chen
Jianguo Feng
Shirong Zhang
Yasi Xu
Jingjing Zhang
Qiong Wu
Mingliang You
Bing Xia
Shenglin Ma

Frontiers in Oncology

doi 10.3389/fonc.2021.644117

5,215 views
9 citations

Articles

G2/M checkpoint regulation and apoptosis facilitate the nuclear egress of parvoviral capsids

G2/M Checkpoint Abrogation With Selective Inhibitors Results in Increased Chromatid Breaks and Radiosensitization of 82-6 hTERT and RPE Human Cells

AMPK Activity Contributes to G2 Arrest and DNA Damage Decrease via p53/p21 Pathways in Oxidatively Damaged Mouse Zygotes

Myt1 overexpression mediates resistance to cell cycle and DNA damage checkpoint kinase inhibitors

Targeting the DNA Damage Response for Cancer Therapy by Inhibiting the Kinase Wee1

DNA damage checkpoint execution and the rules of its disengagement

Stable CDK12 Knock-Out Ovarian Cancer Cells Do Not Show Increased Sensitivity to Cisplatin and PARP Inhibitor Treatment

Effect of safranal on the response of cancer cells to topoisomerase I inhibitors: Does sequence matter?

Milciclib-mediated CDK2 inhibition to boost radiotherapy sensitivity in colorectal cancer

KDM7A-DT induces genotoxic stress, tumorigenesis, and progression of p53 missense mutation-associated invasive breast cancer

Capilliposide C from Lysimachia capillipes Restores Radiosensitivity in Ionizing Radiation-Resistant Lung Cancer Cells Through Regulation of ERRFI1/EGFR/STAT3 Signaling Pathway