Genetic Risk Factor | List of Frontiers open access articles

Mini Review

Published on 18 Jul 2022

Fucosyltransferase 2: A Genetic Risk Factor for Intestinal Diseases

in Microorganisms in Vertebrate Digestive Systems

Mingyang Hu
Xiyun Zhang
Jinze Li
Luotong Chen
Xiaolin He
Tingting Sui

Frontiers in Microbiology

doi 10.3389/fmicb.2022.940196

16,802 views
33 citations

Original Research

Published on 05 Feb 2026

G6PD deficiency as a underrecognized genetic risk factor for rare neurological disorders: evidence from a population-based genetic analysis

in Neurogenomics

Qi Peng
Siping Li
Fen Lv
Xiaomei Zeng
Qingqiu Cheng
Baimao Zhong
Xiaomei Lu

Frontiers in Genetics

doi 10.3389/fgene.2026.1766081

915 views

Original Research

Published on 07 Jun 2021

Characterization of Brain Iron Deposition Pattern and Its Association With Genetic Risk Factor in Alzheimer’s Disease Using Susceptibility-Weighted Imaging

in Brain Imaging and Stimulation

Peiting You
Xiang Li
Zhijiang Wang
Huali Wang
Bin Dong
Quanzheng Li

Frontiers in Human Neuroscience

doi 10.3389/fnhum.2021.654381

6,076 views
17 citations

Perspective

Published on 25 Sep 2020

GBA-Associated Synucleinopathies: Prime Candidates for Alpha-Synuclein Targeting Compounds

in Molecular and Cellular Pathology

Kathrin Brockmann

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2020.562522

4,764 views
13 citations

Original Research

Published on 11 Jan 2018

A Novel RNA Editing Sensor Tool and a Specific Agonist Determine Neuronal Protein Expression of RNA-Edited Glycine Receptors and Identify a Genomic APOBEC1 Dimorphism as a New Genetic Risk Factor of Epilepsy

in Methods and Model Organisms

Svenja Kankowski
Benjamin Förstera
Aline Winkelmann
Pina Knauff
Erich E. Wanker
Xintian A. You
Marcus Semtner
Florian Hetsch
Jochen C. Meier

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2017.00439

6,857 views
24 citations

Review

Published on 04 Jun 2021

Neurodegenerative Disease Risk in Carriers of Autosomal Recessive Disease

in Dementia and Neurodegenerative Diseases

Sophia R. L. Vieira
Huw R. Morris

Frontiers in Neurology

doi 10.3389/fneur.2021.679927

9,003 views
9 citations

Mini Review

Published on 28 Jul 2025

A review on the relationship between the distal 1q21.1 microdeletion and schizophrenia

in Behavioral and Psychiatric Genetics

Xinpeng Guo
Junrong Guo
Xijing Liu
Ting Hu

Frontiers in Genetics

doi 10.3389/fgene.2025.1612654

3,518 views
1 citation

Review

Published on 23 Nov 2018

TREM2 in Alzheimer’s Disease: Microglial Survival and Energy Metabolism

in Alzheimer's Disease and Related Dementias

Honghua Zheng
Baoying Cheng
Yanfang Li
Xin Li
Xiaofen Chen
Yun-wu Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00395

25,624 views
86 citations

Mini Review

Published on 14 Jun 2018

APOE and Alzheimer’s Disease: Neuroimaging of Metabolic and Cerebrovascular Dysfunction

in Alzheimer's Disease and Related Dementias

Jason A. Brandon
Brandon C. Farmer
Holden C. Williams
Lance A. Johnson

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00180

13,255 views
68 citations

Review

Published on 20 Feb 2025

The role of Apolipoprotein E4 on cognitive impairment in Parkinson’s disease and Parkinsonisms

in Neurodegeneration

Angenelle Eve Rosal
Sarah L. Martin
Antonio P. Strafella

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1515374

4,328 views
7 citations

Original Research

Published on 08 Oct 2015

Resveratrol: brain effects on SIRT1, GPR50 and photoperiodic signaling

in Molecular Signalling and Pathways

Joerg R. Leheste
German Torres

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2015.00061

7,151 views
9 citations

Brief Research Report

Published on 16 Feb 2023

Co-occurring pathogenic variants in 6q27 associated with dementia spectrum disorders in a Peruvian family

in Brain Disease Mechanisms

Karla Lucia F. Alvarez
Jorge Alberto Aguilar-Pineda
Michelle M. Ortiz-Manrique
Marluve F. Paredes-Calderon
Bryan C. Cardenas-Quispe
Karin Jannet Vera-Lopez
Luis D. Goyzueta-Mamani
Miguel Angel Chavez-Fumagalli
Gonzalo Davila-Del-Carpio
Antero Peralta-Mestas

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1104585

3,690 views
1 citation

Review

Published on 12 Sep 2024

Fifty years of HLA-associated type 1 diabetes risk: history, current knowledge, and future directions

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Janelle A. Noble

Frontiers in Immunology

doi 10.3389/fimmu.2024.1457213

14,169 views
20 citations

Original Research

Published on 30 Jun 2020

Association Between Glucocerebrosidase Mutations and Parkinson's Disease in Ireland

in Neurogenetics

Diana A. Olszewska
Allan McCarthy
Alexandra I. Soto-Beasley
Ronald L. Walton
Brian Magennis
Russell L. McLaughlin
Orla Hardiman
Owen A. Ross
Tim Lynch

Frontiers in Neurology

doi 10.3389/fneur.2020.00527

7,516 views
22 citations

Hypothesis and Theory

Published on 13 Dec 2012

miRNA-mediated risk for schizophrenia in 22q11.2 deletion syndrome

in RNA

Linda M Brzustowicz
Anne S Bassett

Frontiers in Genetics

doi 10.3389/fgene.2012.00291

7,934 views
37 citations

Brief Research Report

Published on 10 Feb 2026

APOE genotypes are associated with the level of naturally occurring antibodies to amyloid-β in patients with Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Janardan P. Pandey
Aryan M. Namboodiri
Franca Rosa Guerini
Elisabetta Bolognesi
Milena Zanzottera
Roberta Mancuso
Simone Agostini

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1673361

481 views

Articles

Fucosyltransferase 2: A Genetic Risk Factor for Intestinal Diseases

G6PD deficiency as a underrecognized genetic risk factor for rare neurological disorders: evidence from a population-based genetic analysis

Characterization of Brain Iron Deposition Pattern and Its Association With Genetic Risk Factor in Alzheimer’s Disease Using Susceptibility-Weighted Imaging

GBA-Associated Synucleinopathies: Prime Candidates for Alpha-Synuclein Targeting Compounds

A Novel RNA Editing Sensor Tool and a Specific Agonist Determine Neuronal Protein Expression of RNA-Edited Glycine Receptors and Identify a Genomic APOBEC1 Dimorphism as a New Genetic Risk Factor of Epilepsy

Neurodegenerative Disease Risk in Carriers of Autosomal Recessive Disease

A review on the relationship between the distal 1q21.1 microdeletion and schizophrenia

TREM2 in Alzheimer’s Disease: Microglial Survival and Energy Metabolism

APOE and Alzheimer’s Disease: Neuroimaging of Metabolic and Cerebrovascular Dysfunction

The role of Apolipoprotein E4 on cognitive impairment in Parkinson’s disease and Parkinsonisms

Resveratrol: brain effects on SIRT1, GPR50 and photoperiodic signaling

Co-occurring pathogenic variants in 6q27 associated with dementia spectrum disorders in a Peruvian family

Fifty years of HLA-associated type 1 diabetes risk: history, current knowledge, and future directions

Association Between Glucocerebrosidase Mutations and Parkinson's Disease in Ireland

miRNA-mediated risk for schizophrenia in 22q11.2 deletion syndrome

APOE genotypes are associated with the level of naturally occurring antibodies to amyloid-β in patients with Alzheimer’s disease