Hard Problems | List of Frontiers open access articles

Mini Review

Published on 05 Mar 2026

Fatty acid–related immune network in psoriasis: metabolic regulation of innate and adaptive immunity

in Experimental Pharmacology and Drug Discovery

Pengfei Wen
Xiaoxue Zhuo
Siliang Xue

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1731683

149 views

Perspective

Published on 05 Mar 2026

Ethics and bias in emotional AI

in Logic and Reasoning in AI

Smrithy G. S
Balaji Chandrasekaran
Omana J

Frontiers in Artificial Intelligence

doi 10.3389/frai.2026.1768696

Original Research

Published on 05 Mar 2026

Toxoplasma gondii affects trait anxiety in adult ADHD

in ADHD

Alexandra P. Lam
Angelika Carl
Klaus P. Kohse
Alexandra Philipsen

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1766562

308 views

Original Research

Published on 05 Mar 2026

Negative association of hemoglobin levels with mortality in older Japanese patients with dysphagia: a retrospective cohort study

in Geriatric Medicine

Ya-Ting Yuan
Miao Wang
Xian-Zhi Liu
Xiao Cheng
Xue-Ying Cai
Han-Han Chen
Xiao-Bin Zhang

Frontiers in Medicine

doi 10.3389/fmed.2026.1742752

101 views

Case Report

Published on 05 Mar 2026

Case Report: Stage-by-stage fueling, glucose dynamics, and next-day metabolism and biomarker responses after baseline testing in an 18.5-hour Swedish classic tetrathlon

in Sport and Exercise Nutrition

Jonny Trinh
Fredrik Edin
Ulrika Andersson-Hall
Stefan Pettersson

Frontiers in Sports and Active Living

doi 10.3389/fspor.2026.1733702

186 views

Original Research

Published on 05 Mar 2026

Data-driven wear prediction method for complex engineering structures

in Solid and Structural Mechanics

Haibo Zhang
Qingyuan Zhao
Yingxin Zhao
Baiyang Zhao
Meng Zhao
Chuang Liu

Frontiers in Mechanical Engineering

doi 10.3389/fmech.2026.1759085

139 views

Original Research

Published on 05 Mar 2026

Comparison of craniofacial skeletal morphology in pediatric obstructive sleep apnea-hypopnea syndrome patients with class II and class III malocclusions: a retrospective cross-sectional study

in Pediatric Otolaryngology

Lijia Deng
Hongjie Song

Frontiers in Pediatrics

doi 10.3389/fped.2026.1682284

Original Research

Published on 05 Mar 2026

Proximity labelling suggests association of the nonhost receptor PSS1 protein with enzymes of multiple defense pathways in Arabidopsis

in Plant Pathogen Interactions

Oluwatoyosi F. Akintayo
Christian Montes Serey
Justin W. Walley
Madan K. Bhattacharyya

Frontiers in Plant Science

doi 10.3389/fpls.2025.1701640

199 views

Original Research

Published on 05 Mar 2026

Isolation, identification, and antimicrobial effect analysis of active components from Humulus scandens against Phytophthora nicotianae

in Plant Pathogen Interactions

Xiaoyun Wu
Yuxuan Liu
Deqiang Qin
Dongmei Liu
Yongsheng Ren
Jin Tian
Siyue Lan
Xiao Ding
Xiaoping Qin

Frontiers in Plant Science

doi 10.3389/fpls.2026.1753587

Systematic Review

Published on 05 Mar 2026

Cell-type specificity of Tim-3 in respiratory diseases: from mechanisms to clinical translation

in Molecular Innate Immunity

Qi Cui
Jinying Dou
Fukun Wang
Keran Jia

Frontiers in Immunology

doi 10.3389/fimmu.2026.1770761

Original Research

Published on 05 Mar 2026

The impact of trade facilitation on the international competitiveness of agricultural products: a case study of the construction of China’s pilot free trade zones

in Agricultural and Food Economics

Zheng Li
Xiaohui Ding
Jiadi Li

Frontiers in Sustainable Food Systems

doi 10.3389/fsufs.2026.1774748

Original Research

Published on 05 Mar 2026

Decoding the perceived value of Wushu short videos and its influencing factors: an interpretable machine learning analysis based on TikTok videos

in The History, Culture and Sociology of Sports

Yang Chen
Han Wu
Shang Xiang

Frontiers in Sports and Active Living

doi 10.3389/fspor.2026.1688807

190 views

Review

Published on 05 Mar 2026

Novel drugs targeting genetic variants: current applications and future prospects in heart failure treatment

in Molecular Diagnostics and Therapeutics

Xiang Li
Suwen Bai
Yumei Luo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1781854

113 views

Opinion

Published on 05 Mar 2026

Bridging immunization and oral health: a role for paediatric dentists in mitigating vaccine hesitancy in Africa

in Oral Health Promotion

Taofeek Olalekan Ligali
Ahmed Bhayat
Maha El Tantawi
Moréniké Oluwátóyìn Foláyan

Frontiers in Oral Health

doi 10.3389/froh.2026.1751729

Original Research

Published on 05 Mar 2026

Validation of the Korean version of the Self-Dehumanization Scale

in Psychopathology

Khongorzul Khosbayar
Jang-won Seo

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1754166

Case Report

Published on 05 Mar 2026

Case Report: Destructive deep infection of the foot caused by Neoscytalidium dimidiatum leading to great toe amputation

in Microbial Immunology

Huiyu Wang
Yiyun Xu
Hong Li
Ying Chen
Zuocai Wang
Zhenlong Shang
Menglan Zhou
Yingchun Xu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1791879

Articles

Fatty acid–related immune network in psoriasis: metabolic regulation of innate and adaptive immunity

Ethics and bias in emotional AI

Toxoplasma gondii affects trait anxiety in adult ADHD

Negative association of hemoglobin levels with mortality in older Japanese patients with dysphagia: a retrospective cohort study

Case Report: Stage-by-stage fueling, glucose dynamics, and next-day metabolism and biomarker responses after baseline testing in an 18.5-hour Swedish classic tetrathlon

Data-driven wear prediction method for complex engineering structures

Comparison of craniofacial skeletal morphology in pediatric obstructive sleep apnea-hypopnea syndrome patients with class II and class III malocclusions: a retrospective cross-sectional study

Proximity labelling suggests association of the nonhost receptor PSS1 protein with enzymes of multiple defense pathways in Arabidopsis

Isolation, identification, and antimicrobial effect analysis of active components from Humulus scandens against Phytophthora nicotianae

Cell-type specificity of Tim-3 in respiratory diseases: from mechanisms to clinical translation

The impact of trade facilitation on the international competitiveness of agricultural products: a case study of the construction of China’s pilot free trade zones

Decoding the perceived value of Wushu short videos and its influencing factors: an interpretable machine learning analysis based on TikTok videos

Novel drugs targeting genetic variants: current applications and future prospects in heart failure treatment

Bridging immunization and oral health: a role for paediatric dentists in mitigating vaccine hesitancy in Africa

Validation of the Korean version of the Self-Dehumanization Scale

Case Report: Destructive deep infection of the foot caused by Neoscytalidium dimidiatum leading to great toe amputation