Heteroreceptor | List of Frontiers open access articles

Review

Published on 21 Feb 2017

Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease

in Cellular Neurophysiology

Dasiel O. Borroto-Escuela
Jens Carlsson
Patricia Ambrogini
Manuel Narváez
Karolina Wydra
Alexander O. Tarakanov
Xiang Li
Carmelo Millón
Luca Ferraro
Riccardo Cuppini

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2017.00037

44,380 views
124 citations

Review

Published on 10 Jul 2018

Brain Dopamine Transmission in Health and Parkinson's Disease: Modulation of Synaptic Transmission and Plasticity Through Volume Transmission and Dopamine Heteroreceptors

Dasiel O. Borroto-Escuela
Miguel Perez De La Mora
Paul Manger
Manuel Narváez
Sarah Beggiato
Minerva Crespo-Ramírez
Gemma Navarro
Karolina Wydra
Zaida Díaz-Cabiale
Alicia Rivera

Frontiers in Synaptic Neuroscience

doi 10.3389/fnsyn.2018.00020

15,586 views
58 citations

Mini Review

Published on 25 Sep 2019

Oligomeric Receptor Complexes and Their Allosteric Receptor-Receptor Interactions in the Plasma Membrane Represent a New Biological Principle for Integration of Signals in the CNS

in Molecular Signalling and Pathways

Dasiel O. Borroto-Escuela
Kjell Fuxe

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2019.00230

7,417 views
39 citations

Perspective

Published on 06 Feb 2018

Understanding the Role of Adenosine A2AR Heteroreceptor Complexes in Neurodegeneration and Neuroinflammation

in Neurodegeneration

Dasiel O. Borroto-Escuela
Sonja Hinz
Gemma Navarro
Rafael Franco
Christa E. Müller
Kjell Fuxe

Frontiers in Neuroscience

doi 10.3389/fnins.2018.00043

12,688 views
58 citations

Original Research

Published on 12 Feb 2018

Cocaine Effects on Dopaminergic Transmission Depend on a Balance between Sigma-1 and Sigma-2 Receptor Expression

in Molecular Signalling and Pathways

David Aguinaga
Mireia Medrano
Ignacio Vega-Quiroga
Katia Gysling
Enric I. Canela
Gemma Navarro
Rafael Franco

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2018.00017

54,295 views
21 citations

Review

Published on 13 May 2014

Diversity and Bias through Receptor–Receptor Interactions in GPCR Heteroreceptor Complexes. Focus on Examples from Dopamine D2 Receptor Heteromerization

in Molecular and Structural Endocrinology

Kjell Fuxe
Alexander Tarakanov
Wilber Romero Fernandez
Luca Ferraro
Sergio Tanganelli
Malgorzata Filip
Luigi F. Agnati
Pere Garriga
Zaida Diaz-Cabiale
Dasiel O. Borroto-Escuela

Frontiers in Endocrinology

doi 10.3389/fendo.2014.00071

24,107 views
50 citations

Perspective

Published on 20 Aug 2019

Can Allosteric Receptor-Protein Interactions in Receptor Complexes Be a Molecular Mechanism Involved in Cancer Immune Therapy?

in Molecular and Structural Endocrinology

Dasiel O. Borroto-Escuela
Kjell Fuxe

Frontiers in Endocrinology

doi 10.3389/fendo.2019.00574

2,804 views
2 citations

Original Research

Published on 01 May 2018

A Novel Integrative Mechanism in Anxiolytic Behavior Induced by Galanin 2/Neuropeptide Y Y1 Receptor Interactions on Medial Paracapsular Intercalated Amygdala in Rats

in Cellular Neurophysiology

Manuel Narváez
Dasiel O. Borroto-Escuela
Luis Santín
Carmelo Millón
Belén Gago
Antonio Flores-Burgess
Miguel A. Barbancho
Miguel Pérez de la Mora
José Narváez
Zaida Díaz-Cabiale

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2018.00119

5,277 views
20 citations

Perspective

Published on 15 Mar 2021

The Balance of MU-Opioid, Dopamine D2 and Adenosine A2A Heteroreceptor Complexes in the Ventral Striatal-Pallidal GABA Antireward Neurons May Have a Significant Role in Morphine and Cocaine Use Disorders

in Experimental Pharmacology and Drug Discovery

Dasiel O. Borroto-Escuela
Karolina Wydra
Ramon Fores-Pons
Lakshmi Vasudevan
Wilber Romero-Fernandez
Małgorzata Frankowska
Luca Ferraro
Sarah Beggiato
Minerva Crespo-Ramirez
Alicia Rivera

Frontiers in Pharmacology

doi 10.3389/fphar.2021.627032

5,585 views
12 citations

Review

Published on 30 Apr 2019

Overcoming Resistance to Selective Serotonin Reuptake Inhibitors: Targeting Serotonin, Serotonin-1A Receptors and Adult Neuroplasticity

in Neuropharmacology

Faranak Vahid-Ansari
Min Zhang
Amin Zahrai
Paul R. Albert

Frontiers in Neuroscience

doi 10.3389/fnins.2019.00404

31,194 views
58 citations

Review

Published on 08 Dec 2022

The oxytocin receptor represents a key hub in the GPCR heteroreceptor network: potential relevance for brain and behavior

in Molecular Signalling and Pathways

Dasiel O. Borroto-Escuela
Cristina Cuesta-Marti
Alexander Lopez-Salas
Barbara Chruścicka-Smaga
Minerva Crespo-Ramírez
Emiliano Tesoro-Cruz
Daniel A. Palacios-Lagunas
Miguel Perez de la Mora
Harriët Schellekens
Kjell Fuxe

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2022.1055344

12,042 views
37 citations

Original Research

Published on 24 May 2023

Combined treatment with Sigma1R and A2AR agonists fails to inhibit cocaine self-administration despite causing strong antagonistic accumbal A2AR-D2R complex interactions: the potential role of astrocytes

in Neuroplasticity and Development

Dasiel O. Borroto-Escuela
Alexander Lopez-Salas
Karolina Wydra
Marco Bartolini
Zilong Zhou
Malgorzata Frankowska
Agata Suder
Javier Benitez-Porres
Wilber Romero-Fernandez
Malgorzata Filip

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1106765

5,111 views
6 citations

Original Research

Published on 14 Feb 2022

Intranasal Delivery of Galanin 2 and Neuropeptide Y1 Agonists Enhanced Spatial Memory Performance and Neuronal Precursor Cells Proliferation in the Dorsal Hippocampus in Rats

in Neuropharmacology

Dasiel O. Borroto-Escuela
Ramón Fores
Mariana Pita
Miguel A. Barbancho
Pablo Zamorano‐Gonzalez
Natalia García Casares
Kjell Fuxe
Manuel Narváez

Frontiers in Pharmacology

doi 10.3389/fphar.2022.820210

4,984 views
20 citations

Perspective

Published on 15 Feb 2017

IL1R2, CCR2, and CXCR4 May Form Heteroreceptor Complexes with NMDAR and D2R: Relevance for Schizophrenia

in Schizophrenia

Dasiel O. Borroto-Escuela
Alexander O. Tarakanov
Karl Bechter
Kjell Fuxe

Frontiers in Psychiatry

doi 10.3389/fpsyt.2017.00024

5,756 views
16 citations

Original Research

Published on 14 Feb 2024

Neuropeptide Y receptor 1 and galanin receptor 2 (NPY1R-GALR2) interactions in the dentate gyrus and their relevance for neurogenesis and cognition

in Cellular Neurophysiology

Rasiel Beltran-Casanueva
Aracelis Hernández-García
Paula de Amo García
Encarnación Blanco-Reina
Pedro Serrano-Castro
Natalia García-Casares
Kjell Fuxe
Dasiel O. Borroto-Escuela
Manuel Narváez

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2024.1323986

3,969 views
7 citations

Original Research

Published on 30 Aug 2018

Mapping the Interface of a GPCR Dimer: A Structural Model of the A2A Adenosine and D2 Dopamine Receptor Heteromer

in Neuropharmacology

Dasiel O. Borroto-Escuela
David Rodriguez
Wilber Romero-Fernandez
Jon Kapla
Mariama Jaiteh
Anirudh Ranganathan
Tzvetana Lazarova
Kjell Fuxe
Jens Carlsson

Frontiers in Pharmacology

doi 10.3389/fphar.2018.00829

18,360 views
70 citations

Articles

Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease

Brain Dopamine Transmission in Health and Parkinson's Disease: Modulation of Synaptic Transmission and Plasticity Through Volume Transmission and Dopamine Heteroreceptors

Oligomeric Receptor Complexes and Their Allosteric Receptor-Receptor Interactions in the Plasma Membrane Represent a New Biological Principle for Integration of Signals in the CNS

Understanding the Role of Adenosine A2AR Heteroreceptor Complexes in Neurodegeneration and Neuroinflammation

Cocaine Effects on Dopaminergic Transmission Depend on a Balance between Sigma-1 and Sigma-2 Receptor Expression

Diversity and Bias through Receptor–Receptor Interactions in GPCR Heteroreceptor Complexes. Focus on Examples from Dopamine D2 Receptor Heteromerization

Can Allosteric Receptor-Protein Interactions in Receptor Complexes Be a Molecular Mechanism Involved in Cancer Immune Therapy?

A Novel Integrative Mechanism in Anxiolytic Behavior Induced by Galanin 2/Neuropeptide Y Y1 Receptor Interactions on Medial Paracapsular Intercalated Amygdala in Rats

The Balance of MU-Opioid, Dopamine D2 and Adenosine A2A Heteroreceptor Complexes in the Ventral Striatal-Pallidal GABA Antireward Neurons May Have a Significant Role in Morphine and Cocaine Use Disorders

Overcoming Resistance to Selective Serotonin Reuptake Inhibitors: Targeting Serotonin, Serotonin-1A Receptors and Adult Neuroplasticity

The oxytocin receptor represents a key hub in the GPCR heteroreceptor network: potential relevance for brain and behavior

Combined treatment with Sigma1R and A2AR agonists fails to inhibit cocaine self-administration despite causing strong antagonistic accumbal A2AR-D2R complex interactions: the potential role of astrocytes

Intranasal Delivery of Galanin 2 and Neuropeptide Y1 Agonists Enhanced Spatial Memory Performance and Neuronal Precursor Cells Proliferation in the Dorsal Hippocampus in Rats

IL1R2, CCR2, and CXCR4 May Form Heteroreceptor Complexes with NMDAR and D2R: Relevance for Schizophrenia

Neuropeptide Y receptor 1 and galanin receptor 2 (NPY1R-GALR2) interactions in the dentate gyrus and their relevance for neurogenesis and cognition

Mapping the Interface of a GPCR Dimer: A Structural Model of the A2A Adenosine and D2 Dopamine Receptor Heteromer