Heuristic Function | List of Frontiers open access articles

Original Research

Published on 13 May 2026

Stereoselective effects of nicotine enantiomers on the gut-brain axis and neuroinflammation in a mouse model of Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Ruixia Liu
Yunu Ma
Yingyan Li
Xia Gao
Shu Wang
Lutao Xu
Guanglin Liu
Huan Chen
Min Ji
Hongwei Hou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1823372

245 views

Case Report

Published on 13 May 2026

Case Report: Twenty years of metreleptin therapy in congenital generalized lipodystrophy type 1: the longest reported follow-up to date

in Clinical Diabetes

Elise Van der Borght
Bart Van der Schueren
Roman Vangoitsenhoven
David Cassiman
Baris Akinci
Rebecca J. Brown
Elif A. Oral
Ann Mertens
Pieter-Jan Martens

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1815903

281 views

Mini Review

Published on 13 May 2026

The role of EZH2 dysregulation in the pathogenesis of B-cell lymphomas and its implications as a target therapy

in Hematologic Malignancies

Myrna Candelaria

Frontiers in Oncology

doi 10.3389/fonc.2026.1843273

209 views

Mini Review

Published on 13 May 2026

Wnt signaling as a regulator of memory T cells: implications for CAR-T cell therapy

in Cancer Immunity and Immunotherapy

Tatiana Fourfouris
Ki Jun Lee
Samantha Hurwitz
Asher Ahdoot
Alexander Lee
Maiah Zarrabi
Michael Kahn
Yong-Mi Kim

Frontiers in Immunology

doi 10.3389/fimmu.2026.1843548

189 views

Review

Published on 13 May 2026

Neutrophil extracellular traps in gout: from immune defense to pathological dynamic equilibrium

in Inflammation

Fangfang Wang
Ning Tie
Yong Jin
Hongbin Li

Frontiers in Immunology

doi 10.3389/fimmu.2026.1826191

205 views

Hypothesis and Theory

Published on 13 May 2026

Neutrosophic technarrative architecture for symbolic–emotional evaluation of virtual architectural spaces in VR

in Virtual Reality and Human Behaviour

Jesus Rafael Hechavarria-Hernandez
Leonel Vasquez-Cevallos
Florentin Smarandache

Frontiers in Virtual Reality

doi 10.3389/frvir.2026.1818469

342 views

Brief Research Report

Published on 13 May 2026

Modifying implementation strategies for integration of screening and management of mental disorders, including substance use disorders into other NCD care in Faridabad, Haryana as part of ICMR-MINDS project

in Public Mental Health

Yatan Pal Singh Balhara
Neha Dahiya
Tweesha Chhatbar
Parag Bhardwaj
Siddharth Sarkar
Hitesh Verma
Kuldeep Singh
Gerish Atri
Om Pal Singh Saini
Pulkit Verma

Frontiers in Public Health

doi 10.3389/fpubh.2026.1734787

418 views

Original Research

Published on 13 May 2026

Proteins at the intersection of circadian rhythms and metabolic dysfunction-associated steatotic liver disease: an 18-protein panel as a novel predictive biomarker set

in Translational and Clinical Endocrinology

Yiyi Wang
Qilong Zhai
Xuemei Lian
Lei Zhao

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1836392

166 views

Original Research

Published on 13 May 2026

The impact of sports participation on subjective wellbeing among Chinese young adults: exploring the chain mediation effect of perceived social support and psychological resilience

in Public Mental Health

Xinchun Wang
Minmin Du
Tongnian Yang
Zhihui Li
Huiyu Shi
Jian Yang
Xinrou Wan

Frontiers in Public Health

doi 10.3389/fpubh.2026.1841181

358 views

Original Research

Published on 13 May 2026

Phenotype-driven protocol switching is associated with improved ART outcomes under constant gonadotropin dosage: a self-controlled analysis of 4,632 cycles

in Reproduction

Jie Gao
Yiran Li

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1816340

181 views

Original Research

Published on 13 May 2026

Pan-tumor validation of FoundationOne®CDx as a companion diagnostic for RET fusions as a predictor of response to selpercatinib

in Cancer Molecular Targets and Therapeutics

Allison van den Hout
Richard S. P. Huang
Caleb Ho
David L. Smith
Douglas A. Mata
Baljinder Kaur
Sameera R. Wijayawardana
Jennifer Wright
Anna M. Szpurka
Douglas I. Lin

Frontiers in Oncology

doi 10.3389/fonc.2026.1820286

270 views

Original Research

Published on 13 May 2026

Association of steroid regimens and withdrawal with relapse risk in myasthenia gravis: a real-world cohort study

in Neuromuscular Disorders and Peripheral Neuropathies

Yangyu Huang
Ying Tan
Jingwen Yan
Yuzhou Guan

Frontiers in Neurology

doi 10.3389/fneur.2026.1792705

264 views

Original Research

Published on 13 May 2026

Using native human sera to assess the suitability of external quality assessment materials based on testosterone, progesterone, and 17β-estradiol measurements

in Molecular Diagnostics and Therapeutics

Laura Vierbaum
Patricia Kaiser
Thomas Keller
Stephan Weber
Ingo Schellenberg
Peter B. Luppa
Folker Wenzel
Mario Thevis

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1758376

293 views

Original Research

Published on 13 May 2026

Dietary habits and their association with irritable bowel syndrome among the public population in Saudi Arabia: a multicenter based study

in Public Health and Nutrition

Shereen Ahmed A. Qalawa
Mohamed Goda Elbqry
Fatma Mohamed Elmansy
Aryam Tariq Almunif
Bashayr Falah Alharbi
Reema Jazzaa Alharbi
Joud Abdullah Alharbi
Kadi Matar Alharbi
Shaden Abdulaziz Almuhaysin
Shahad Turki Almutairi

Frontiers in Public Health

doi 10.3389/fpubh.2026.1804238

248 views

Original Research

Published on 13 May 2026

Genomic insights into population structure and conservation of wild olive (Olea europaea subsp. cuspidata) in Oman’s Dhofar and Hajar Mountains

in Plant Systematics and Evolution

Thuraiya Al Jabri
Boshra Ahmed Halo
Alastair Culham
Richard Ellis

Frontiers in Plant Science

doi 10.3389/fpls.2026.1813482

277 views

Review

Published on 13 May 2026

Multimechanistic actions of functional factors in enhancing physical strength and endurance: a scoping review of nutritional basis and natural extracts

in Sport and Exercise Nutrition

Xiangyu Huang
Jingjing Zhu
Peng Zang
Junli Chen
Pu Chen
Nan Xu
Wei Liu

Frontiers in Sports and Active Living

doi 10.3389/fspor.2026.1819117

528 views

Articles

Stereoselective effects of nicotine enantiomers on the gut-brain axis and neuroinflammation in a mouse model of Parkinson’s disease

Case Report: Twenty years of metreleptin therapy in congenital generalized lipodystrophy type 1: the longest reported follow-up to date

The role of EZH2 dysregulation in the pathogenesis of B-cell lymphomas and its implications as a target therapy

Wnt signaling as a regulator of memory T cells: implications for CAR-T cell therapy

Neutrophil extracellular traps in gout: from immune defense to pathological dynamic equilibrium

Neutrosophic technarrative architecture for symbolic–emotional evaluation of virtual architectural spaces in VR

Modifying implementation strategies for integration of screening and management of mental disorders, including substance use disorders into other NCD care in Faridabad, Haryana as part of ICMR-MINDS project

Proteins at the intersection of circadian rhythms and metabolic dysfunction-associated steatotic liver disease: an 18-protein panel as a novel predictive biomarker set

The impact of sports participation on subjective wellbeing among Chinese young adults: exploring the chain mediation effect of perceived social support and psychological resilience

Phenotype-driven protocol switching is associated with improved ART outcomes under constant gonadotropin dosage: a self-controlled analysis of 4,632 cycles

Pan-tumor validation of FoundationOne®CDx as a companion diagnostic for RET fusions as a predictor of response to selpercatinib

Association of steroid regimens and withdrawal with relapse risk in myasthenia gravis: a real-world cohort study

Using native human sera to assess the suitability of external quality assessment materials based on testosterone, progesterone, and 17β-estradiol measurements

Dietary habits and their association with irritable bowel syndrome among the public population in Saudi Arabia: a multicenter based study

Genomic insights into population structure and conservation of wild olive (Olea europaea subsp. cuspidata) in Oman’s Dhofar and Hajar Mountains

Multimechanistic actions of functional factors in enhancing physical strength and endurance: a scoping review of nutritional basis and natural extracts