High Functionality | List of Frontiers open access articles

Original Research

Published on 27 Feb 2026

Comprehensive analyses of biological function and tumor microenvironment with cuproptosis regulators and construction of a cuproptosis-related scoring system in thyroid cancer based on bioinformatics and experimental validation

in Cancer Genetics and Oncogenomics

Shitong Su
Jiaqi Han
Zijian Liu
Kun Tian

Frontiers in Genetics

doi 10.3389/fgene.2026.1735093

Original Research

Published on 27 Feb 2026

Exploring the effects of combined Nordic and reverse Nordic hamstring exercises on physical fitness in prepubertal male soccer players

in Elite Sports and Performance Enhancement

Senda Sammoud
Yassine Negra
Raja Bouguezzi
Aaron Uthoff
Jason Moran
Helmi Chaabene

Frontiers in Sports and Active Living

doi 10.3389/fspor.2026.1717594

160 views

Original Research

Published on 27 Feb 2026

The indirect effect of physical activity on aggression among university student-athletes: the mediating role of state anger

in Sport Psychology

Sevim Handan Yılmaz
Mert Ayrancı
Murat Sarıkabak
Mehmet Kemal Aydın
Metin Kuş
Abdulmenaf Korkutata
Murat Çelebi
Mehmet Civan

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1717868

Case Report

Published on 27 Feb 2026

Concomitant occurrence of primary gastric sarcomatoid carcinoma and giant gastrointestinal stromal tumor: a case report and literature review

in Gastrointestinal Cancers: Gastric and Esophageal Cancers

Yujuan Dai
Jianhao Yang
Qiaozhen Li
LuSheng Wen
Xianying Chen
Yihui Wang
Lan Zhang
Dachao Chen

Frontiers in Oncology

doi 10.3389/fonc.2026.1757830

Original Research

Published on 27 Feb 2026

Comparative genomic and ecological insights into Salmonella enterica serovar Kumasi ST2302 from the first Asian clinical isolate

in Infectious Agents and Disease

Shijie Peng
Yan Chen
Taigui Chen
Jun Wang
Peijun Lv
Yanan Wang
Xuebin Xu
Yibin Zhou
Yue Liu

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1746150

299 views

Brief Research Report

Published on 27 Feb 2026

Higher education teachers’ perspectives on the ethical challenges of using artificial intelligence—a case study in the Alto Alentejo region, Portugal

in Higher Education

Ana Paula Oliveira
Margarida Coelho
Orlanda Póvoa
Bruno Morgado
Cristina Guerra

Frontiers in Education

doi 10.3389/feduc.2026.1780142

216 views

Review

Published on 27 Feb 2026

Digitalisation of medicine in LMICs (sub-Saharan Africa): enablers, barriers, and funding strategies for sustainable health systems

in Digital Public Health

Sandra Nanyonga
Peter Blanshard
Lisa Maria Crevola
Daniel Simeon-Dubach

Frontiers in Public Health

doi 10.3389/fpubh.2026.1710904

111 views

Original Research

Published on 27 Feb 2026

Development of a novel duplex crystal digital PCR for the detection of PRRSV–1 and PRRSV–2

in Veterinary and Zoonotic Infection

Yuwen Shi
Jiakang He
Kaichuang Shi
Yanwen Yin
Feng Long
Shuping Feng
Zuzhang Wei

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2026.1701517

149 views

Original Research

Published on 27 Feb 2026

Microbial community patterns in two geochemically contrasting zones within the alkaline lake Bagno dell'Acqua (Pantelleria Island, Italy)

in Extreme Microbiology

Agnese Piacentini
Stefano Amalfitano
Barbara Casentini
Andrea Butturini
Ilaria Mazzini
Marco Seminara
Emanuele Colica
Francesco Giuseppe Falese
Francesco Latino Chiocci
Cristina Mazzoni

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1773453

108 views

Case Report

Published on 27 Feb 2026

Penile involvement associated with renal pelvic squamous cell carcinoma: a case report and mechanistic considerations

in Genitourinary Oncology

Kotaro Masaki
Takuya Tsujino
Hiroyuki Okada
Yuki Yoshikawa
Ryoichi Maenosono
Yusaku Imura
Masashi Sanada
Kensuke Hirosuna
Yuta Furusawa
Rei Yoshimi

Frontiers in Oncology

doi 10.3389/fonc.2026.1761194

Review

Published on 27 Feb 2026

Tumor-infiltrating lymphocyte therapy in triple-negative breast cancer: from mechanistic exploration to clinical translation

in T Cell Biology

Yongxi Wang
Zhe Zhang
Zhuo Chen
Xiaoyun Xie
Fang Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1741333

130 views

Review

Published on 27 Feb 2026

Ferroptosis reshapes the tumor immune microenvironment: molecular mechanisms, immune regulation, and therapeutic synergistic strategies

in Cancer Immunity and Immunotherapy

Zhuangwei Lv
Zixian Liu
Ziru Nie
Ning Li
Lingbei Kong
Fangfang Shen
Junna Jiao
Hui Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1772259

Review

Published on 27 Feb 2026

From passive monitoring to active engagement: a systematic review and meta-analysis of digital health technologies for improving objective physical activity and cardiorespiratory fitness in patients with obstructive sleep apnea

in Digital Public Health

Jingkang Xia
Jiayi Yao
Haozhe Wang
Yongliang Zhu
Lihong Mao
Xueqiang Zhu

Frontiers in Public Health

doi 10.3389/fpubh.2026.1760571

119 views

Review

Published on 27 Feb 2026

Epigenetic and mitoepigenetic regulation in cancer and therapeutic perspectives

in Pharmacology of Anti-Cancer Drugs

Selcen Celik-Uzuner
Ihsan Nalkiran
Ugur Uzuner
Hatice Sevim Nalkiran

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1760013

140 views

Original Research

Published on 27 Feb 2026

Predicting the acute pancreatitis severity with multi-machine learning models: constructing an online prediction platform

in Clinical and Diagnostic Microbiology and Immunology

Jie Cao
Shike Long
Huan Liu
Ribin Liao
Fu,an Chen
Xiyou Li
Lifeng Xu
Ying Liu

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2026.1760036

Editorial

Published on 27 Feb 2026

Editorial: Prevention and treatment of urolithiasis: innovation and novel techniques

in Genitourinary Surgery and Interventions

Steffi Kar Kei Yuen
Bo Xiao
Bhaskar Somani

Frontiers in Surgery

doi 10.3389/fsurg.2026.1785032

Articles

Comprehensive analyses of biological function and tumor microenvironment with cuproptosis regulators and construction of a cuproptosis-related scoring system in thyroid cancer based on bioinformatics and experimental validation

Exploring the effects of combined Nordic and reverse Nordic hamstring exercises on physical fitness in prepubertal male soccer players

The indirect effect of physical activity on aggression among university student-athletes: the mediating role of state anger

Concomitant occurrence of primary gastric sarcomatoid carcinoma and giant gastrointestinal stromal tumor: a case report and literature review

Comparative genomic and ecological insights into Salmonella enterica serovar Kumasi ST2302 from the first Asian clinical isolate

Higher education teachers’ perspectives on the ethical challenges of using artificial intelligence—a case study in the Alto Alentejo region, Portugal

Digitalisation of medicine in LMICs (sub-Saharan Africa): enablers, barriers, and funding strategies for sustainable health systems

Development of a novel duplex crystal digital PCR for the detection of PRRSV–1 and PRRSV–2

Microbial community patterns in two geochemically contrasting zones within the alkaline lake Bagno dell'Acqua (Pantelleria Island, Italy)

Penile involvement associated with renal pelvic squamous cell carcinoma: a case report and mechanistic considerations

Tumor-infiltrating lymphocyte therapy in triple-negative breast cancer: from mechanistic exploration to clinical translation

Ferroptosis reshapes the tumor immune microenvironment: molecular mechanisms, immune regulation, and therapeutic synergistic strategies

From passive monitoring to active engagement: a systematic review and meta-analysis of digital health technologies for improving objective physical activity and cardiorespiratory fitness in patients with obstructive sleep apnea

Epigenetic and mitoepigenetic regulation in cancer and therapeutic perspectives

Predicting the acute pancreatitis severity with multi-machine learning models: constructing an online prediction platform

Editorial: Prevention and treatment of urolithiasis: innovation and novel techniques