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5 articles related to "Hiroaki Kimura"

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Articles

Original Research

Published on 03 Nov 2025

Immune tolerance induction using the thyrotropin receptor epitope 78–94 (p37) prevents Graves’ disease in HLA-DR3 transgenic mice

in Immunological Tolerance and Regulation

Hiroaki Kimura
Hidefumi Inaba
Itsuki Nonaka
Daiki Hashimoto
Moritoshi Hirono
Shuhei Morita
Hiroshi Iwakura
Takashi Akamizu
Masanori Nakata

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633350

1,830 views
1 citation

Review

Published on 08 Aug 2022

Review: Precise sarcoma patient-derived orthotopic xenograft (PDOX) mouse models enable identification of novel effective combination therapies with the cyclin-dependent kinase inhibitor palbociclib: A strategy for clinical application

in Pharmacology of Anti-Cancer Drugs

Hiroaki Kimura
Takashi Higuchi
Kentaro Igarashi
Norio Yamamoto
Katsuhiro Hayashi
Shinji Miwa
Michael Bouvet
Hiroyuki Tsuchiya
Robert M. Hoffman

Frontiers in Oncology

doi 10.3389/fonc.2022.957844

5,160 views
16 citations

Original Research

Published on 08 Dec 2025

Human fibrosarcoma cells selected for ultra-high doxorubicin resistance, acquire trabectedin cross-resistance, remain sensitive to recombinant methioninase, and have increased c-MYC expression

in Pharmacology of Anti-Cancer Drugs

Hiroaki Kimura
Sei Morinaga
Qinghong Han
Kohei Mizuta
Byung Mo Kang
Michael Bouvet
Norio Yamamoto
Katsuhiro Hayashi
Shinji Miwa
Kentaro Igarashi

Frontiers in Oncology

doi 10.3389/fonc.2025.1704021

1,104 views

Original Research

Published on 06 Apr 2023

Amino acid polymorphisms in human histocompatibility leukocyte antigen class II and proinsulin epitope have impacts on type 1 diabetes mellitus induced by immune-checkpoint inhibitors

in Cancer Immunity and Immunotherapy

Hiroaki Kimura
Hidefumi Inaba
Shuhei Morita
Daisuke Kosugi
Yuki Asai
Yosuke Kaido
Saya Ito
Tomonao Hirobata
Gen Inoue
Yuki Yamamoto

Frontiers in Immunology

doi 10.3389/fimmu.2023.1165004

4,201 views
9 citations

Original Research

Published on 18 Dec 2020

A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation by Autophagy Induction

in Inflammation

Chun-Hsien Wu
Chin Heng Gan
Lan-Hui Li
Jen-Che Chang
Shin-Tai Chen
Mridula P. Menon
Shu-Meng Cheng
Shih-Ping Yang
Chen-Lung Ho
Oleg V. Chernikov

Frontiers in Immunology

doi 10.3389/fimmu.2020.607564

7,590 views
14 citations