Hit Compounds Optimization | List of Frontiers open access articles

Review

Published on 04 Mar 2026

Lens epithelial cells senescence in cataract pathogenesis and emerging therapeutic opportunities

in Molecular and Cellular Pathology

Liangning Cui
Yiyi Wang
Lijun Wang
Jianhao Bai
Wanru Zhou
Manhui Zhu
Jianjun Zhou
Haiying Jin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1758898

Original Research

Published on 04 Mar 2026

AI for adaptive science teaching: strengthening teacher self-efficacy and perceived usefulness

in Digital Education

Mathea Brückner
Christoph Thyssen
Johannes Huwer

Frontiers in Education

doi 10.3389/feduc.2026.1759274

Brief Research Report

Published on 04 Mar 2026

Visualization of thermal interference effects in energy piles using transparent soil

in Interdisciplinary Physics

Renrong Li
Yancheng Liu
Yang Zhou

Frontiers in Physics

doi 10.3389/fphy.2026.1753194

Original Research

Published on 04 Mar 2026

The involvement of miRNAs in the enhanced immune response of oysters via haemocyte-mediated immune priming

in Comparative Immunology

Xiaoxu Zhou
Lixin Guo
Weilin Wang
Lingyuan Song
Yuefeng Dai
Jiajun Zuo
Lingling Wang
Linsheng Song

Frontiers in Immunology

doi 10.3389/fimmu.2026.1753252

Original Research

Published on 04 Mar 2026

Association between NPAR and cognitive impairment in peritoneal dialysis patients

in Nutrition, Psychology and Brain Health

Conghui Liu
Feng Shao
Xiaoqi Wang
Jiajie Cai
Zhongxin Li

Frontiers in Nutrition

doi 10.3389/fnut.2026.1752923

Original Research

Published on 04 Mar 2026

Diagnostic odyssey of patients with the rare immunodeficiency activated PI3 kinase delta syndrome (APDS): case study from expert and patient surveys

in Primary Immunodeficiencies

Hermann Maximilian Wolf
Fabio Candotti
Roman Spelsberg
Georgios Sogkas
Hans-Holger Bleß
Kirsten H. Herrmann
Fabian Hauck

Frontiers in Immunology

doi 10.3389/fimmu.2026.1763482

213 views

Original Research

Published on 04 Mar 2026

Association of plasma ferritin and plasma iron at time of vaccination with the immune response to SARS-CoV-2 vaccination: a longitudinal cohort study

in Nutritional Immunology

Giulia Pestoni
Dominik Menges
Craig Fenwick
Pornpimol Scheuchzer
Julia Braun
Sarah R. Haile
Tala Ballouz
Christophe Zeder
Nicole U. Stoffel
Michael B. Zimmermann

Frontiers in Immunology

doi 10.3389/fimmu.2026.1764884

244 views

Original Research

Published on 04 Mar 2026

PD-1 blockade does not enhance alloimmunization after allogeneic dendritic cell vaccination in cancer patients

in Alloimmunity and Transplantation

Severine Planel
Guillaume Vayssière
Gianni Maggipinto
Estelle Leplus
Karine Laulagnier
Florence Renard
Francoise Myster
Marie Gerard
Ingel Demedts
Kristof Cuppens

Frontiers in Immunology

doi 10.3389/fimmu.2026.1763434

243 views

Original Research

Published on 04 Mar 2026

SIRT1 regulates glycolysis and angiogenesis of ovarian cancer through β-catenin/c-Myc/PKM2, and its mechanism in chemotherapy resistance

in Gynecological Oncology

Chengju Zhang
Hu Wang
Yu Zhou
Deng He
Tiantian Feng
Xi Wang
Shangqi Ni
Juan Zhang

Frontiers in Oncology

doi 10.3389/fonc.2026.1762850

Original Research

Published on 04 Mar 2026

Effects of weighted vests versus elastic bands plyometric jump training on lower-body physical performance adaptations in volleyball players

in Exercise Physiology

Yichen Bao
Yuankai Qiao
Shuowen Yang

Frontiers in Physiology

doi 10.3389/fphys.2026.1756391

Original Research

Published on 04 Mar 2026

Ascorbic acid enhances in vitro primordial germ cell-like cell differentiation from mouse ESCs

in Stem Cell Research

Umesh Kumar
Nithyapriya Kumar
P. Chandra Shekar
Kumarasamy Thangaraj

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1755998

463 views

Original Research

Published on 04 Mar 2026

Multi-site screening for Pneumocystis jirovecii in lung cancer: possible tumour tissue colonization

in Clinical Infectious Diseases

Magdalena Szydłowicz
Żaneta Zajączkowska
Mariusz Chabowski
Maciej Nowicki
Błażej Łukianowski
Pawel Gajdzis
Martin Kváč
Enrique J. Calderón
Solène Le Gal
Marta Kicia

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2026.1755638

131 views

Original Research

Published on 04 Mar 2026

Dynamic graph based attention spectral network for motor imagery-brain computer interface

in Brain-Computer Interfaces

Zexiong Shao
Zhenghui Gu
Le Che
Zhuliang Yu
Yuanqing Li

Frontiers in Human Neuroscience

doi 10.3389/fnhum.2026.1755549

402 views

Original Research

Published on 04 Mar 2026

Network-enhanced machine learning framework for multi crop yield prediction: a comprehensive analysis of indian agricultural data

in Agroecological Cropping Systems

Shinyclimensa C
Parthiban A

Frontiers in Agronomy

doi 10.3389/fagro.2026.1767878

451 views

Original Research

Published on 04 Mar 2026

Development and validation of a nomogram prediction model for cardiovascular comorbidities in COPD patients based on hypertension

in Pulmonary Medicine

Zhaojun Chen
Huan Li
Yuli Cai
Xuliang Chen
Deyi Zhou
Yihuan Su
Chaofeng Lin
Liangde Li
Dongjie Huang
Riken Chen

Frontiers in Medicine

doi 10.3389/fmed.2026.1766827

Original Research

Published on 04 Mar 2026

Dual - functional cRGD/pH - sensitive liposomes loaded with sorafenib: a novel therapeutic approach for hepatocellular carcinoma

in Biomedical Nanotechnology

Xu Yang
Guangchun Sun
Xiaoyu Zhou
Qing Liang
Jing Liu

Frontiers in Nanotechnology

doi 10.3389/fnano.2026.1760783

155 views

Articles

Lens epithelial cells senescence in cataract pathogenesis and emerging therapeutic opportunities

AI for adaptive science teaching: strengthening teacher self-efficacy and perceived usefulness

Visualization of thermal interference effects in energy piles using transparent soil

The involvement of miRNAs in the enhanced immune response of oysters via haemocyte-mediated immune priming

Association between NPAR and cognitive impairment in peritoneal dialysis patients

Diagnostic odyssey of patients with the rare immunodeficiency activated PI3 kinase delta syndrome (APDS): case study from expert and patient surveys

Association of plasma ferritin and plasma iron at time of vaccination with the immune response to SARS-CoV-2 vaccination: a longitudinal cohort study

PD-1 blockade does not enhance alloimmunization after allogeneic dendritic cell vaccination in cancer patients

SIRT1 regulates glycolysis and angiogenesis of ovarian cancer through β-catenin/c-Myc/PKM2, and its mechanism in chemotherapy resistance

Effects of weighted vests versus elastic bands plyometric jump training on lower-body physical performance adaptations in volleyball players

Ascorbic acid enhances in vitro primordial germ cell-like cell differentiation from mouse ESCs

Multi-site screening for Pneumocystis jirovecii in lung cancer: possible tumour tissue colonization

Dynamic graph based attention spectral network for motor imagery-brain computer interface

Network-enhanced machine learning framework for multi crop yield prediction: a comprehensive analysis of indian agricultural data

Development and validation of a nomogram prediction model for cardiovascular comorbidities in COPD patients based on hypertension

Dual - functional cRGD/pH - sensitive liposomes loaded with sorafenib: a novel therapeutic approach for hepatocellular carcinoma