Hpv Negative | List of Frontiers open access articles

Original Research

Accepted on 25 Mar 2026

Metabolic reprogramming of cholesterol biosynthesis drives macrophage-mediated immune suppression in HPV-negative cervical adenocarcinoma

in Cancer Immunity and Immunotherapy

Jianing Zhang
Wenjuan Wei
Yajun Zhang
Daqing Wang

Frontiers in Immunology

185 views

Original Research

Published on 11 Jan 2024

Human papillomavirus-associated head and neck squamous cell carcinoma cells rely on glycolysis and display reduced oxidative phosphorylation

in Cancer Metabolism

Nora Li
Imen Chamkha
Gaurav Verma
Sabine Swoboda
Malin Lindstedt
Lennart Greiff
Eskil Elmér
Johannes Ehinger

Frontiers in Oncology

doi 10.3389/fonc.2023.1304106

4,301 views
10 citations

Mini Review

Published on 03 Dec 2019

Enhanced Radiation Sensitivity of Human Papillomavirus-Driven Head and Neck Cancer: Focus on Immunological Aspects

in Cancer Immunity and Immunotherapy

Mine Özcan-Wahlbrink
Christoph Schifflers
Angelika B. Riemer

Frontiers in Immunology

doi 10.3389/fimmu.2019.02831

7,008 views
21 citations

Original Research

Published on 16 Aug 2022

Effectiveness of PARP inhibition in enhancing the radiosensitivity of 3D spheroids of head and neck squamous cell carcinoma

in Head and Neck Cancer

Chumin Zhou
Maria Rita Fabbrizi
Jonathan R. Hughes
Gabrielle J. Grundy
Jason L. Parsons

Frontiers in Oncology

doi 10.3389/fonc.2022.940377

6,522 views
19 citations

Review

Published on 17 Feb 2021

Human Papillomavirus-Negative Cervical Cancer: A Comprehensive Review

in Women's Cancer

Biyuan Xing
Jianfeng Guo
Yuhan Sheng
Gang Wu
Yingchao Zhao

Frontiers in Oncology

doi 10.3389/fonc.2020.606335

65,266 views
112 citations

Original Research

Published on 11 Feb 2021

Increased Abundance of Tumour-Associated Neutrophils in HPV-Negative Compared to HPV-Positive Oropharyngeal Squamous Cell Carcinoma Is Mediated by IL-1R Signalling

in Oral Cancers

Sarmad Al-Sahaf
Naeima B. Hendawi
Bethany Ollington
Robert Bolt
Penelope D. Ottewell
Keith D. Hunter
Craig Murdoch

Frontiers in Oral Health

doi 10.3389/froh.2021.604565

5,765 views
16 citations

Review

Published on 11 Apr 2012

New Concepts for Translational Head and Neck Oncology: Lessons from HPV-Related Oropharyngeal Squamous Cell Carcinomas

in Head and Neck Cancer

Efterpi Kostareli
Dana Holzinger
Jochen Hess

Frontiers in Oncology

doi 10.3389/fonc.2012.00036

11,729 views
38 citations

Original Research

Published on 26 Jan 2023

Oral health in HPV-positive and HPV-negative patients with oropharyngeal squamous cell carcinoma

in Head and Neck Cancer

Philipp Kanzow
Katharina Mielke
Valentina Hrasky
Susanne Wiegand
Henning Schliephake
Dirk Beutner
Annette Wiegand

Frontiers in Oncology

doi 10.3389/fonc.2023.1083067

3,986 views
5 citations

Original Research

Published on 11 Jun 2021

EGFR and PI3K Pathway Activities Might Guide Drug Repurposing in HPV-Negative Head and Neck Cancers

in Head and Neck Cancer

Andreas Mock
Michaela Plath
Julius Moratin
Maria Johanna Tapken
Dirk Jäger
Jürgen Krauss
Stefan Fröhling
Jochen Hess
Karim Zaoui

Frontiers in Oncology

doi 10.3389/fonc.2021.678966

7,089 views
31 citations

Original Research

Published on 31 May 2021

Survival Outcomes and Treatment Decision by Human Papillomavirus Status Among Patients With Stage IVC Head and Neck Squamous Cell Carcinoma

in Head and Neck Cancer

Ping Zhou
Yi-Feng Yu
Chen-Lu Lian
Jun Wang
Ren-Gong Zhuo
San-Gang Wu

Frontiers in Oncology

doi 10.3389/fonc.2021.668066

10,984 views
21 citations

Original Research

Published on 08 Aug 2023

The genetic variant rs55986091 HLA-DQB1 is associated with a protective effect against cervical cancer

in Gynecological Oncology

Michael A. Vinokurov
Konstantin O. Mironov
Elvira A. Domonova
Tatiana N. Romanyuk
Anna A. Popova
Vasiliy G. Akimkin

Frontiers in Oncology

doi 10.3389/fonc.2023.1207935

2,898 views
5 citations

Original Research

Published on 16 Jul 2019

TLR9 Mediated Tumor-Stroma Interactions in Human Papilloma Virus (HPV)-Positive Head and Neck Squamous Cell Carcinoma Up-Regulate PD-L1 and PD-L2

in Cancer Immunity and Immunotherapy

Paramita Baruah
Jessica Bullenkamp
Philip O. G. Wilson
Michael Lee
Juan Carlos Kaski
Ingrid E. Dumitriu

Frontiers in Immunology

doi 10.3389/fimmu.2019.01644

8,026 views
30 citations

Original Research

Published on 16 Sep 2025

Integrated multi-omics analysis of single-cell and spatial transcriptomics reveals distinct hpv-associated immune microenvironment features and prognostic signatures in cervical cancer

in Cancer Immunity and Immunotherapy

Qiuyue Su
Xiangdong Tian
Fucheng Li
Xi Yu
Wenchen Gong
Yurong Chen
Jianan Wang
Siqi Yang
Shaojun Zhang
Qian Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612623

5,892 views
7 citations

Original Research

Published on 18 Oct 2024

Human papillomavirus infection affects the immune microenvironment and antigen presentation in penile cancer

in Genitourinary Oncology

Sulayne Janayna Araujo Guimarães
André Alvares Marques Vale
Mirtes Castelo Branco Rocha
Ana Luiza de Araújo Butarelli
Jenilson Mota da Silva
Amanda Jordão Silva de Deus
Leudivan Nogueira
Ronald Wagner Pereira Coelho
Silma Regina Pereira
Ana Paula Silva Azevedo-Santos

Frontiers in Oncology

doi 10.3389/fonc.2024.1463445

2,810 views
6 citations

Original Research

Published on 11 Dec 2018

The Use of HPV16-E5, EGFR, and pEGFR as Prognostic Biomarkers for Oropharyngeal Cancer Patients

in Head and Neck Cancer

Miren Taberna
Montserrat Torres
María Alejo
Marisa Mena
Sara Tous
Sandra Marquez
Miquel A. Pavón
Xavier León
Jacinto García
Marta Guix

Frontiers in Oncology

doi 10.3389/fonc.2018.00589

6,244 views
24 citations

Original Research

Published on 04 Apr 2018

CDKN2A Copy Number Loss Is an Independent Prognostic Factor in HPV-Negative Head and Neck Squamous Cell Carcinoma

in Head and Neck Cancer

William S. Chen
Ranjit S. Bindra
Allen Mo
Thomas Hayman
Zain Husain
Joseph N. Contessa
Stephen G. Gaffney
Jeffrey P. Townsend
James B. Yu

Frontiers in Oncology

doi 10.3389/fonc.2018.00095

7,305 views
58 citations

Articles

Metabolic reprogramming of cholesterol biosynthesis drives macrophage-mediated immune suppression in HPV-negative cervical adenocarcinoma

Human papillomavirus-associated head and neck squamous cell carcinoma cells rely on glycolysis and display reduced oxidative phosphorylation

Enhanced Radiation Sensitivity of Human Papillomavirus-Driven Head and Neck Cancer: Focus on Immunological Aspects

Effectiveness of PARP inhibition in enhancing the radiosensitivity of 3D spheroids of head and neck squamous cell carcinoma

Human Papillomavirus-Negative Cervical Cancer: A Comprehensive Review

Increased Abundance of Tumour-Associated Neutrophils in HPV-Negative Compared to HPV-Positive Oropharyngeal Squamous Cell Carcinoma Is Mediated by IL-1R Signalling

New Concepts for Translational Head and Neck Oncology: Lessons from HPV-Related Oropharyngeal Squamous Cell Carcinomas

Oral health in HPV-positive and HPV-negative patients with oropharyngeal squamous cell carcinoma

EGFR and PI3K Pathway Activities Might Guide Drug Repurposing in HPV-Negative Head and Neck Cancers

Survival Outcomes and Treatment Decision by Human Papillomavirus Status Among Patients With Stage IVC Head and Neck Squamous Cell Carcinoma

The genetic variant rs55986091 HLA-DQB1 is associated with a protective effect against cervical cancer

TLR9 Mediated Tumor-Stroma Interactions in Human Papilloma Virus (HPV)-Positive Head and Neck Squamous Cell Carcinoma Up-Regulate PD-L1 and PD-L2

Integrated multi-omics analysis of single-cell and spatial transcriptomics reveals distinct hpv-associated immune microenvironment features and prognostic signatures in cervical cancer

Human papillomavirus infection affects the immune microenvironment and antigen presentation in penile cancer

The Use of HPV16-E5, EGFR, and pEGFR as Prognostic Biomarkers for Oropharyngeal Cancer Patients

CDKN2A Copy Number Loss Is an Independent Prognostic Factor in HPV-Negative Head and Neck Squamous Cell Carcinoma