Hypoxic Adaptation | List of Frontiers open access articles

Original Research

Published on 26 Aug 2025

Effects of all-trans retinoic acid and oxygen concentration on the proliferation and differentiation of subcutaneous adipocytes in yak

in Animal Nutrition and Metabolism

Sibinuer Yasenjian
Su Shan
Yuqi Zhe
Yuqing Zhang
Zhixin Chai

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1643818

1,590 views

Mini Review

Published on 03 Sep 2025

Reframing SpO2 tolerance as a physiological switch: implications for hypoxic adaptation and exercise regulation

in Exercise Physiology

Enomoto Yuri
Hui-Yu Chung
Fu-Shih Chen

Frontiers in Physiology

doi 10.3389/fphys.2025.1667238

3,732 views
1 citation

Original Research

Published on 21 May 2021

Whole-Transcriptome Analysis of Yak and Cattle Heart Tissues Reveals Regulatory Pathways Associated With High-Altitude Adaptation

in Livestock Genomics

Hui Wang
Jincheng Zhong
Jikun Wang
Zhixin Chai
Chengfu Zhang
Jinwei Xin
Jiabo Wang
Xin Cai
Zhijuan Wu
Qiumei Ji

Frontiers in Genetics

doi 10.3389/fgene.2021.579800

7,093 views
18 citations

Review

Published on 05 Nov 2025

The gut microbiota in high-altitude medicine: intersection of hypoxic adaptation and disease management

in Microorganisms in Vertebrate Digestive Systems

Qian Chen
Demei Huang
Junling Liu
Nan Jia
Zherui Shen
Caixia Pei
Chen Chen
Yuhan Liu
Yilan Wang
Shihua Shi

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1705487

3,451 views
2 citations

Original Research

Published on 09 Dec 2025

Transcriptome analysis reveals physiological responses in liver tissues of Epinephelus cyanopodus under acute hypoxic stress

in Aquatic Physiology

Qiaoyi Chen
Yukun Huang
Zhiya Yu
Wenjie He
Xueqin Hu
Jinhui Wu
Tianguang Cai
Yuhua Cui
Along Gao
Hu Shu

Frontiers in Physiology

doi 10.3389/fphys.2025.1697398

990 views

Original Research

Published on 15 Apr 2021

KLF4, a Key Regulator of a Transitive Triplet, Acts on the TGF-β Signaling Pathway and Contributes to High-Altitude Adaptation of Tibetan Pigs

in Evolutionary and Population Genetics

Tao Wang
Yuanyuan Guo
Shengwei Liu
Chaoxin Zhang
Tongyan Cui
Kun Ding
Peng Wang
Xibiao Wang
Zhipeng Wang

Frontiers in Genetics

doi 10.3389/fgene.2021.628192

6,630 views
13 citations

Review

Published on 30 Aug 2024

Hypoxia-induced epigenetic regulation of breast cancer progression and the tumour microenvironment

in Cell Growth and Division

Alina L. Capatina
Jodie R. Malcolm
Jack Stenning
Rachael L. Moore
Katherine S. Bridge
William J. Brackenbury
Andrew N. Holding

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2024.1421629

6,986 views
17 citations

Review

Published on 12 Dec 2016

Diaphragm Muscle Adaptation to Sustained Hypoxia: Lessons from Animal Models with Relevance to High Altitude and Chronic Respiratory Diseases

in Respiratory Physiology and Pathophysiology

Philip Lewis
Ken D. O'Halloran

Frontiers in Physiology

doi 10.3389/fphys.2016.00623

8,630 views
24 citations

Original Research

Published on 26 Jan 2022

The Complete Mitogenome of Elymus sibiricus and Insights Into Its Evolutionary Pattern Based on Simple Repeat Sequences of Seed Plant Mitogenomes

in Plant Systematics and Evolution

Yanli Xiong
Qingqing Yu
Yi Xiong
Junming Zhao
Xiong Lei
Lin Liu
Wei Liu
Yan Peng
Jianbo Zhang
Daxu Li

Frontiers in Plant Science

doi 10.3389/fpls.2021.802321

5,096 views
49 citations

Original Research

Published on 24 May 2024

Orphan response regulator NnaR is critical for nitrate and nitrite assimilation in Mycobacterium abscessus

in Molecular Bacterial Pathogenesis

Breven S. Simcox
Kyle H. Rohde

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2024.1411333

3,186 views
3 citations

Original Research

Published on 10 Jun 2022

Systemic Blood Predictors of Elevated Pulmonary Artery Pressure Assessed by Non-invasive Echocardiography After Acute Exposure to High Altitude: A Prospective Cohort Study

in General Cardiovascular Medicine

Shi-Zhu Bian
Chen Zhang
Rong-Sheng Rao
Xiao-Han Ding
Lan Huang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2022.866093

3,255 views
5 citations

Articles

Effects of all-trans retinoic acid and oxygen concentration on the proliferation and differentiation of subcutaneous adipocytes in yak

Reframing SpO2 tolerance as a physiological switch: implications for hypoxic adaptation and exercise regulation

Whole-Transcriptome Analysis of Yak and Cattle Heart Tissues Reveals Regulatory Pathways Associated With High-Altitude Adaptation

The gut microbiota in high-altitude medicine: intersection of hypoxic adaptation and disease management

Transcriptome analysis reveals physiological responses in liver tissues of Epinephelus cyanopodus under acute hypoxic stress

KLF4, a Key Regulator of a Transitive Triplet, Acts on the TGF-β Signaling Pathway and Contributes to High-Altitude Adaptation of Tibetan Pigs

Hypoxia-induced epigenetic regulation of breast cancer progression and the tumour microenvironment

Diaphragm Muscle Adaptation to Sustained Hypoxia: Lessons from Animal Models with Relevance to High Altitude and Chronic Respiratory Diseases

The Complete Mitogenome of Elymus sibiricus and Insights Into Its Evolutionary Pattern Based on Simple Repeat Sequences of Seed Plant Mitogenomes

Orphan response regulator NnaR is critical for nitrate and nitrite assimilation in Mycobacterium abscessus

Systemic Blood Predictors of Elevated Pulmonary Artery Pressure Assessed by Non-invasive Echocardiography After Acute Exposure to High Altitude: A Prospective Cohort Study