Ill Structured Problems | List of Frontiers open access articles

Original Research

Published on 03 Mar 2026

Incidence, prevalence, and global burden of myocarditis among individuals aged 65 and older from 1990 to 2021 across 204 countries: a critical re-analysis of data from the global burden of disease study

in Cardiovascular Epidemiology and Prevention

Ang Li
Jingyu Tan
Jing Hu
Yongyi Bai

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1611616

Original Research

Published on 03 Mar 2026

Design and application of enhanced extended state observer for improving bus voltage stability during EIS testing of multi-stack proton exchange membrane fuel cells

in Fuel Cells, Electrolyzers and Membrane Reactors

Kai Zhao
Zhihao Song
Shuming Xu
Fuhua Fan
Jian Mei
Chuanyu Sun

Frontiers in Energy Research

doi 10.3389/fenrg.2026.1731457

200 views

Clinical Trial

Published on 03 Mar 2026

Multi-strain probiotic reduces gastrointestinal side effects in women with elevated HOMA-IR index treated with metformin: a 12-week randomised controlled trial

in Clinical Diabetes

Marzena Ratajczak
Agnieszka Bilska
Katarzyna Musialik
Karolina Skonieczna-Żydecka
Igor Łoniewski
Anna Gogojewicz
Joanna Karolkiewicz

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1765741

107 views

Original Research

Published on 03 Mar 2026

Metatranscriptomics reveals the horse gut RNA virome and a viral sharing network with human and domestic animals

in One Health

Can Li
Kaiping Liu
Ni Wei
Shengwei Hu
Xiaoyue Li
Cunyuan Li

Frontiers in Veterinary Science

doi 10.3389/fvets.2026.1755551

120 views

Original Research

Published on 03 Mar 2026

Situational self-assertion in self–other dilemmas among young adults in five cultures: negotiations between self and others

in Human Developmental Psychology

Mika Hirai
Susie D. Lamborn

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1766805

114 views

Original Research

Published on 03 Mar 2026

Phosphoproteomics uncovers a neuroimmune perspective on trigeminal neuralgia: sexually dimorphic regulatory networks linking calcium channels to the complement cascade

in Multiple Sclerosis and Neuroimmunology

Xiaojie Zhai
Xianghong Lin
Linlin Zhang
Yuxuan Ren
He Miao
Mengmeng Miao
Yijun Chen
Yiwei Zhang
Changshun Huang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1676019

105 views

Original Research

Published on 03 Mar 2026

Polysaccharides from Psoralea corylifolia alleviate CTX-induced immunosuppression in mice by modulating gut microbiota- metabolite-immune signaling

in Nutritional Immunology

Zhenhua Yin
Guangyu Hong
Hao Zhang
Juanjuan Zhang
Qingfeng Guo
Kun Li
Li Wang
Lin Chen

Frontiers in Immunology

doi 10.3389/fimmu.2026.1759122

Review

Published on 03 Mar 2026

Neurovascular coupling and cerebrovascular reactivity: physiology, lifespan development, pathophysiology, and clinical relevance

in Vascular Physiology

Zena Khartabil
David Kala
Yeva Prysiazhniuk
Jakub Otáhal

Frontiers in Physiology

doi 10.3389/fphys.2026.1728065

154 views

Review

Published on 03 Mar 2026

A comprehensive review of mechanisms underlying resistance to immune checkpoint inhibitors

in Cancer Immunity and Immunotherapy

Alexandre Bertucci
Khaoula Taleb
Emilien Billon
Téo Fernez
Philippe Rochigneux

Frontiers in Immunology

doi 10.3389/fimmu.2026.1735741

100 views

Case Report

Published on 03 Mar 2026

High-grade prostatic stromal sarcoma with a distinctive cystic-solid MRI pattern and aggressive clinical course: a case report

in Genitourinary Oncology

Xiaoyan Lei
Kehui Liu
Fujin Liu
Shishi Luo

Frontiers in Oncology

doi 10.3389/fonc.2026.1762973

Review

Published on 03 Mar 2026

The role and mechanisms of bone microenvironment regulators in osteoporosis: novel intervention strategies for addressing the challenges of aging

in Bone Research

Hongyuan Yao
Yutao Cui
Peng Li
Shouye Sun
Chuangang Peng
Dankai Wu

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1783422

Original Research

Published on 03 Mar 2026

False belief attribution in toddlers: an exploratory study with a novel unexpected-identity task

in Development in Infancy

Ilaria Grazzani
Elisabetta Conte
Edoardo Datteri

Frontiers in Developmental Psychology

doi 10.3389/fdpys.2026.1727052

Mini Review

Published on 03 Mar 2026

Personalized resilience: how individual variability in brain–immune responses to stress influences the development of anxiety disorders

in Cellular Neurophysiology

Nadine Peixoto
Rosalina Fonseca

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2026.1745994

209 views

Original Research

Published on 03 Mar 2026

Gui Shen Wan ameliorates PCOS-like cellular phenotypes by suppressing TNF-α-mediated inflammation and restoring the PI3K/Akt signaling pathway

in Inflammation

Yan Lu
Lingtong Li
Jia Fang
Wenjuan Ju
Yanfang Yan
Feihua Wu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1739230

Editorial

Published on 03 Mar 2026

Editorial: Mechanistic, machine learning and hybrid models of the ‘other’ endocrine regulatory systems in health and disease, volume II

in Systems Endocrinology

Joseph DiStefano
Johannes W. Dietrich
Uri Alon

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1806508

Case Report

Published on 03 Mar 2026

Case Report: A case of diffuse midline glioma, H3 K27-altered presenting with long-segment spinal cord lesions

in Neuro-Oncology and Neurosurgical Oncology

Chengcheng Lu
Songke Lu
Rongrong Li
Rui Pang
Ruijiao Zhao
Yao Cui
Jianguo Zhang
Wei Li
Huiqin Liu

Frontiers in Oncology

doi 10.3389/fonc.2026.1658494

Articles

Incidence, prevalence, and global burden of myocarditis among individuals aged 65 and older from 1990 to 2021 across 204 countries: a critical re-analysis of data from the global burden of disease study

Design and application of enhanced extended state observer for improving bus voltage stability during EIS testing of multi-stack proton exchange membrane fuel cells

Multi-strain probiotic reduces gastrointestinal side effects in women with elevated HOMA-IR index treated with metformin: a 12-week randomised controlled trial

Metatranscriptomics reveals the horse gut RNA virome and a viral sharing network with human and domestic animals

Situational self-assertion in self–other dilemmas among young adults in five cultures: negotiations between self and others

Phosphoproteomics uncovers a neuroimmune perspective on trigeminal neuralgia: sexually dimorphic regulatory networks linking calcium channels to the complement cascade

Polysaccharides from Psoralea corylifolia alleviate CTX-induced immunosuppression in mice by modulating gut microbiota- metabolite-immune signaling

Neurovascular coupling and cerebrovascular reactivity: physiology, lifespan development, pathophysiology, and clinical relevance

A comprehensive review of mechanisms underlying resistance to immune checkpoint inhibitors

High-grade prostatic stromal sarcoma with a distinctive cystic-solid MRI pattern and aggressive clinical course: a case report

The role and mechanisms of bone microenvironment regulators in osteoporosis: novel intervention strategies for addressing the challenges of aging

False belief attribution in toddlers: an exploratory study with a novel unexpected-identity task

Personalized resilience: how individual variability in brain–immune responses to stress influences the development of anxiety disorders

Gui Shen Wan ameliorates PCOS-like cellular phenotypes by suppressing TNF-α-mediated inflammation and restoring the PI3K/Akt signaling pathway

Editorial: Mechanistic, machine learning and hybrid models of the ‘other’ endocrine regulatory systems in health and disease, volume II

Case Report: A case of diffuse midline glioma, H3 K27-altered presenting with long-segment spinal cord lesions