CASE REPORT article
Front. Oncol.
Sec. Genitourinary Oncology
High-Grade Prostatic Stromal Sarcoma with a Distinctive Cystic-Solid MRI Pattern and Aggressive Clinical Course: A Case Report
Lei Xiaoyan 1
Kehui Liu 2
Fujin Liu 3
Shishi Luo 1
1. Department of Radiology, Hainan General Hospital, Haikou, China
2. Haikou People's Hospital, Haikou, China
3. Hainan General Hospital, Haikou, China
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Abstract
Objectives To report a rare case of high-grade prostatic stromal sarcoma (PSS) and delineate its characteristic magnetic resonance imaging (MRI) features to facilitate early detection and accurate diagnosis. Methods A 55-year-old male presented with progressive dysuria. Preoperative multiparametric pelvic MRI was performed. The imaging findings were correlated with histopathology from a robot-assisted laparoscopic radical prostatectomy. Results MRI revealed a large, well-demarcated, encapsulated cystic-solid mass within the prostate. The solid components showed restricted diffusion. The cystic component contained multiple septations and demonstrated no diffusion restriction. A involvement nodule was identified in the right seminal vesicle. Histopathology confirmed high-grade prostatic stromal sarcoma with positive surgical margins. The patient experienced local recurrence within six months despite adjuvant chemotherapy. Conclusions Prostatic stromal sarcoma is a rare malignancy with distinct MRI features that can help differentiate it from more common prostatic neoplasms.
Summary
Keywords
case report, high-grade, MRI, Prostate, PSS, Stromal sarcoma
Received
08 December 2025
Accepted
18 February 2026
Copyright
© 2026 Xiaoyan, Liu, Liu and Luo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Shishi Luo
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