Jak Inhibitors | List of Frontiers open access articles

Original Research

Published on 09 Oct 2025

Metabolomics integrated with network pharmacology and serum-urine pharmacochemistry unveils the antidiabetic mechanism of Anemarrhenae Rhizoma

in Diabetes: Molecular Mechanisms

Xunlong Zhong
Huaidong Peng
Chang Xiao
Chunhua Xiao
Xinyu Zhu
Haixuan Liang
Ruolun Wang
Yanmei Zhong
Jingwen Feng

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1618584

288 views

Opinion

Published on 09 Oct 2025

Potential strategies for combination therapy involving medicines with differential signal transduction regulation effects and the mechanism of action of minocycline in septic neuroinflammation

in Inflammation Pharmacology

Kazuhiro Itoh
Hiroshi Tsutani
Yasuhiko Mitsuke
Masamichi Ikawa
Hiromichi Iwasaki

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1691613

208 views

Original Research

Published on 09 Oct 2025

Identification of the wbtF gene as a cytotoxicity-associated factor in Francisella novicida infection

in Bacteria and Host

Dhandy Koesoemo Wardhana
Takashi Shimizu
Kenta Watanabe
Akihiko Uda
Masahisa Watarai

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1647652

352 views

Original Research

Published on 09 Oct 2025

Multimodal reprogramming of the tumor microenvironment by MMR and dual checkpoint blockade in hepatocellular carcinoma models

in Cancer Immunity and Immunotherapy

Mulu Z. Tesfay
Aleksandra Cios
Khandoker Usran Ferdous
Randal S. Shelton
Bahaa Mustafa
Camila C. Simoes
Murat Gokden
Isabelle R. Miousse
Kimberly J. Krager
Marjan Boerma

Frontiers in Immunology

doi 10.3389/fimmu.2025.1679665

293 views

Original Research

Published on 09 Oct 2025

Development of a convolutional neural network-based AI-assisted multi-task colonoscopy withdrawal quality control system (with video)

in Gastrointestinal Sciences

Jian Chen
Menglin Zhu
Zhijia Shen
Kaijian Xia
Xiaodan Xu
Ganhong Wang

Frontiers in Physiology

doi 10.3389/fphys.2025.1666311

266 views

Original Research

Published on 09 Oct 2025

A hybrid voice cloning for inclusive education in low-resource environments

in Human-Media Interaction

Muhammad Mohtad Younus
Arshad Iqbal
Esha e Noor Durrani
Naveed Ahmad
Mohamad Ladan

Frontiers in Computer Science

doi 10.3389/fcomp.2025.1675616

584 views

Review

Published on 09 Oct 2025

Cancer-derived exosomes: mediators of immune crosstalk and emerging targets for immunotherapy

in Cancer Immunity and Immunotherapy

Ridwan Mahamed
Bernice Monchusi
Clement Penny
Sheefa Mirza

Frontiers in Immunology

doi 10.3389/fimmu.2025.1679934

190 views

Review

Published on 09 Oct 2025

Coumarins in the tumor-immune application: from molecular mechanisms to therapeutic innovations

in Cancer Immunity and Immunotherapy

Yufan Zhao
Lingjie Jing
Leng Han
Cheng Guo
Quanjun Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1681892

108 views

Review

Published on 09 Oct 2025

Gaming disorder and problematic caffeine consumption in adolescents: a narrative review and public health framework

in Addictive Behaviors

Jennifer J. Park
Yihong Zhao
Marc N. Potenza

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1690304

812 views

Original Research

Published on 09 Oct 2025

Prognostic genes related to mitochondrial dynamics and mitophagy in diffuse large B-cell lymphoma are identified and validated using an integrated analysis of bulk and single-cell RNA sequencing

in Cancer Immunity and Immunotherapy

Qingjiao Chen
Mingui Chen
Jizhen Wang
Jinfeng Dong
Apeng Yang
Xiaolin Zhu
Qiaoxian Lin
Jinlong Huang
Guilan Lai
Meihong Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1686948

255 views

Original Research

Published on 09 Oct 2025

Remifentanil reduces post-induction hypotension compared to fentanyl in thoracoscopic esophagectomy: a retrospective cohort study

in Translational Pharmacology

Jin Zhang
Chen Zhao
Hao Sun
Youming Deng
Guangfu Qian
Shibing Teng
Baoxin Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1660228

700 views

Original Research

Published on 09 Oct 2025

Determinants of healthcare expenditures: evidence from Türkiye’s healthcare system

in Health Economics

Hülya Diğer
Kübranur Çebi Karaaslan
Ahmet Köstekçi
Abdullah Göv

Frontiers in Public Health

doi 10.3389/fpubh.2025.1632883

765 views

Mini Review

Published on 09 Oct 2025

Population pharmacokinetic modeling in radiopharmaceutical therapy: a review

in Dosimetry and Radiation Safety

Deni Hardiansyah
Bisma Barron Patrianesha
Gerhard Glatting

Frontiers in Nuclear Medicine

doi 10.3389/fnume.2025.1695332

189 views

Original Research

Published on 09 Oct 2025

Zoning of urban territorial spaces: evaluating socio-economic-ecological low-carbon development efficiency in Xuzhou, China

in Social-Ecological Urban Systems

Pin Liu
Xiang Ji
Dong Wang
Deping Jiang
Xiaochun Hong

Frontiers in Environmental Science

doi 10.3389/fenvs.2025.1636744

395 views

Original Research

Published on 09 Oct 2025

Exploring climate adaptation in UAE residential communities: temperature trends, awareness, and technology adoption

in Urban Science

Khaula Alkaabi
Chafik Bouhaddioui
Salieu Senghore
Saif Obaid Al Darmaki

Frontiers in Built Environment

doi 10.3389/fbuil.2025.1602348

451 views

Original Research

Published on 09 Oct 2025

Retrospective analysis of incidence, fracture pattern and treatment of zygomatic complex fracture in a dental teaching institute in India

in Oral and Maxillofacial Surgery

Somya Pande
Uday Londhe
Kalyani Bhate
Aditya Jape

Frontiers in Oral Health

doi 10.3389/froh.2025.1674963

303 views

Articles

Metabolomics integrated with network pharmacology and serum-urine pharmacochemistry unveils the antidiabetic mechanism of Anemarrhenae Rhizoma

Potential strategies for combination therapy involving medicines with differential signal transduction regulation effects and the mechanism of action of minocycline in septic neuroinflammation

Identification of the wbtF gene as a cytotoxicity-associated factor in Francisella novicida infection

Multimodal reprogramming of the tumor microenvironment by MMR and dual checkpoint blockade in hepatocellular carcinoma models

Development of a convolutional neural network-based AI-assisted multi-task colonoscopy withdrawal quality control system (with video)

A hybrid voice cloning for inclusive education in low-resource environments

Cancer-derived exosomes: mediators of immune crosstalk and emerging targets for immunotherapy

Coumarins in the tumor-immune application: from molecular mechanisms to therapeutic innovations

Gaming disorder and problematic caffeine consumption in adolescents: a narrative review and public health framework

Prognostic genes related to mitochondrial dynamics and mitophagy in diffuse large B-cell lymphoma are identified and validated using an integrated analysis of bulk and single-cell RNA sequencing

Remifentanil reduces post-induction hypotension compared to fentanyl in thoracoscopic esophagectomy: a retrospective cohort study

Determinants of healthcare expenditures: evidence from Türkiye’s healthcare system

Population pharmacokinetic modeling in radiopharmaceutical therapy: a review

Zoning of urban territorial spaces: evaluating socio-economic-ecological low-carbon development efficiency in Xuzhou, China

Exploring climate adaptation in UAE residential communities: temperature trends, awareness, and technology adoption

Retrospective analysis of incidence, fracture pattern and treatment of zygomatic complex fracture in a dental teaching institute in India