Large Scale Problems | List of Frontiers open access articles

Clinical Trial

Published on 04 Mar 2026

JK5G postbiotics modulate gut microbiota and metabolome to alleviate cancer-related pain: a randomized controlled trial with multi-omics integration

in Nutritional Immunology

Mengting Chen
Junhui Zhang
Hong Yang
Lei Lei
Liejun Yang
Sixiong Wang
Huiqing Yu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1764491

145 views

Original Research

Published on 04 Mar 2026

Upregulation of miR-146a-5p and miR-146b-5p limits IL-1β-mediated signaling in adipose tissue during polytrauma by downregulating IRAK1

in Inflammation

Antonia Mortsch
Julian Roos
Rebecca Halbgebauer
Ludmila Lupu
Annette Palmer
Anja Werberger
Ulrich Stifel
Martin Wabitsch
Markus Huber-Lang
Julia Zinngrebe

Frontiers in Immunology

doi 10.3389/fimmu.2026.1658504

Original Research

Published on 04 Mar 2026

Differential modulation of tomato root exudates by Streptomyces strains underlies contrasting control of Fusarium oxysporum f. sp. lycopersici

in Plant Pathogen Interactions

Valerio Mattei
Kjell Sergeant
Marco Saracchi
Daniela Bulgari
Andrea Kunova
Cristina Pizzatti
Paolo Cortesi
Jenny Renaut
Matias Pasquali

Frontiers in Plant Science

doi 10.3389/fpls.2026.1759226

204 views

Systematic Review

Published on 04 Mar 2026

Natural medicines for radioprotection and radiosensitization: a bibliometric analysis of mechanisms and trends (2001–2025)

in Radiation Oncology

Yupeng Di
Jiazhao Song
Yingjie Wang
Lingling Meng
Jing Li

Frontiers in Oncology

doi 10.3389/fonc.2026.1792854

Systematic Review

Published on 04 Mar 2026

Mind–body exercise for improving balance, aerobic capacity, walking ability, muscle strength, and mental health in patients with type 2 diabetes: a network meta-analysis

in Clinical Diabetes

Fuwei Wu
Yanling Yuan
Yingchun Hou
Zhen Ye

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1749651

100 views

Original Research

Published on 04 Mar 2026

Sleep problems in autistic children and adolescents: an age-stratified approach

in Human Developmental Psychology

Antonio Paone
Maria Grazia Logrieco
Silvia Guerrera
Elisa Fucà
Laura Casula
Alessandra Minutolo
Stefano Vicari
Giovanni Valeri

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1715093

Original Research

Published on 04 Mar 2026

Dynamic monitoring of immunoglobulin G as a prognostic indicator after curative resection in high-risk stage II–III colorectal cancer: a retrospective cohort study

in Gastrointestinal Cancers: Colorectal Cancer

Junyi Sun
Feng Guo
Yinfang Guo
Ni Wang
Jiangxue Feng

Frontiers in Oncology

doi 10.3389/fonc.2026.1753074

Original Research

Published on 04 Mar 2026

Cultural barriers to stunting prevention: a case study of the Baduy indigenous tribe in Indonesia

in Medical Sociology

Yustia Atsanatrilova Adi
Sri Hilmi Pujihartati
Rahesli Humsona
Dyke Gita Wirasisya

Frontiers in Sociology

doi 10.3389/fsoc.2026.1724639

325 views

Original Research

Published on 04 Mar 2026

Lexical vs. structural cue use in L2 prediction: filler-gap parsing ability shapes learners' information use

in Psycholinguistics

Chie Nakamura
Suzanne Flynn
Yoichi Miyamoto
Noriaki Yusa

Frontiers in Language Sciences

doi 10.3389/flang.2026.1756463

149 views

Perspective

Published on 04 Mar 2026

Brain mechanisms underlying self-other distinction for bodily self-recognition

Yuuki G. Oka
Masaki Isoda

Frontiers in Neural Circuits

doi 10.3389/fncir.2026.1781653

Brief Research Report

Published on 04 Mar 2026

Different types of electrostimulation target specific impaired sensory and motor functions in chemotherapy-induced peripheral neuropathy: a secondary analysis of a controlled trial

in Neurorehabilitation

Florian Rieder
Robert Sassmann
Yvonne Theres Kienberger
Vanessa Castagnaviz
Dagmar Schaffler-Schaden
Tim Johansson
Gabriel Rinnerthaler
Maria Flamm
Richard Greil
Christoph Schulze

Frontiers in Neurology

doi 10.3389/fneur.2026.1653161

117 views

Original Research

Published on 04 Mar 2026

Optimized ridge-furrow ratio regulated soil nutrients, promoted grain filling and increased wheat yield

in Crop and Product Physiology

Kun Liu
Yu Shi
Zhenwen Yu
Yongli Zhang
Zhen Zhang

Frontiers in Plant Science

doi 10.3389/fpls.2026.1776299

Original Research

Published on 04 Mar 2026

Molecular epidemiology and genomic analysis of bulbul coronavirus in Guangdong, China

in Zoological Medicine

Lina Zhang
Shuting Chen
Huihua Li
Lixia Li
Hao Liu

Frontiers in Veterinary Science

doi 10.3389/fvets.2026.1659863

283 views

Original Research

Published on 04 Mar 2026

Trends and projections of global testicular cancer burden from 1990 to 2035

in Cancer Epidemiology and Prevention

Changkun Mao
Chengpin Tao
Chao Yang
Jian Shen
Guangyuan Li

Frontiers in Oncology

doi 10.3389/fonc.2026.1634710

Original Research

Published on 04 Mar 2026

Exploring the neuroprotective mechanism of Tongqiao Huashuan granules in vascular dementia based on PLCγ1/IP3R signaling pathway

in Alzheimer's Disease and Related Dementias

Xianhui Huang
Jiajia Liu
Yanna Ren
Dingding Liu
Jing Cai
Liping Cao
Tong Lei
Yuanhua Wu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1719664

Original Research

Published on 04 Mar 2026

CT-assessment of carotid plaque features and their impact on residual stenosis after stenting

in Endovascular and Interventional Neurology

Lu Li
Ting Ting Li
Qing Yuan Wang
Yu Meng Sun
Zhen Jia Wang
Su Nan Xu
Wei Yu

Frontiers in Neurology

doi 10.3389/fneur.2026.1767502

Articles

JK5G postbiotics modulate gut microbiota and metabolome to alleviate cancer-related pain: a randomized controlled trial with multi-omics integration

Upregulation of miR-146a-5p and miR-146b-5p limits IL-1β-mediated signaling in adipose tissue during polytrauma by downregulating IRAK1

Differential modulation of tomato root exudates by Streptomyces strains underlies contrasting control of Fusarium oxysporum f. sp. lycopersici

Natural medicines for radioprotection and radiosensitization: a bibliometric analysis of mechanisms and trends (2001–2025)

Mind–body exercise for improving balance, aerobic capacity, walking ability, muscle strength, and mental health in patients with type 2 diabetes: a network meta-analysis

Sleep problems in autistic children and adolescents: an age-stratified approach

Dynamic monitoring of immunoglobulin G as a prognostic indicator after curative resection in high-risk stage II–III colorectal cancer: a retrospective cohort study

Cultural barriers to stunting prevention: a case study of the Baduy indigenous tribe in Indonesia

Lexical vs. structural cue use in L2 prediction: filler-gap parsing ability shapes learners' information use

Brain mechanisms underlying self-other distinction for bodily self-recognition

Different types of electrostimulation target specific impaired sensory and motor functions in chemotherapy-induced peripheral neuropathy: a secondary analysis of a controlled trial

Optimized ridge-furrow ratio regulated soil nutrients, promoted grain filling and increased wheat yield

Molecular epidemiology and genomic analysis of bulbul coronavirus in Guangdong, China

Trends and projections of global testicular cancer burden from 1990 to 2035

Exploring the neuroprotective mechanism of Tongqiao Huashuan granules in vascular dementia based on PLCγ1/IP3R signaling pathway

CT-assessment of carotid plaque features and their impact on residual stenosis after stenting