Lead Article | List of Frontiers open access articles

Systematic Review

Published on 14 May 2026

First-line immunotherapy for advanced hepatocellular carcinoma: a network meta-analysis of randomized trials with overall and HBV/HCV-stratified efficacy and safety

in Cancer Immunity and Immunotherapy

Wei Chen
Boyan Chen
Chunbin Hu
Qiance Wei
Lili Zhang
Wenwen Fu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1693251

181 views

Review

Published on 14 May 2026

Adoptive cell therapies in solid tumors: current clinical landscape, challenges, and future directions

in Cancer Immunity and Immunotherapy

Joe Rizkallah
Bahaa El Deen Wehbeh
Waseem Wassouf
Elio Salameh
Adnan Joumaa
Francois Jose Haddad
Lama Hamade
Nicole Charbel
Ghada M. Bakri
Ali Awada

Frontiers in Immunology

doi 10.3389/fimmu.2026.1800292

341 views

Original Research

Published on 14 May 2026

Spiritual leadership, flourishing, organizational commitment, and productivity of nurses in healthcare crisis contexts

in Employee Well-being and Health

Malehlwa Constance Madimabe
Freda Van Der Walt
Malefetsane Ephraim Thasi

Frontiers in Organizational Psychology

doi 10.3389/forgp.2026.1795291

296 views

Original Research

Published on 14 May 2026

Reference intervals for plasma IFN-α, TNF-α, IL-12p70, and IFN-γ by flow cytometry in healthy adults from eastern China: a single-center study

in Cytokines and Soluble Mediators in Immunity

Qian Liu
Linru Zhang
Xuanxuan Jiao
Yefu Sun
Fang Yang
Fumeng Yang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1806685

186 views

Original Research

Published on 14 May 2026

Mesenteric perfusion at rest and during feeding in healthy children

in Systems Interactions and Organ Networks

Kathryn E. Tobert
Kathryn Higdon
Theresa A. Mikhailov
John P. Scott
Wendi Redfern
George M. Hoffman

Frontiers in Network Physiology

doi 10.3389/fnetp.2026.1739687

297 views

Original Research

Published on 14 May 2026

A novel glycolipid composite index predicting cardiovascular disease in Chinese adults with abnormal glucose metabolism: a nationwide cohort study

in Cardiovascular Epidemiology and Prevention

Dan-dan Peng
Ping Zhu
Ji-chen Xie
Wei Yong
Kai Ye
Jun-jie Gao
Zhao-xia Shuai

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1791890

323 views

Original Research

Published on 14 May 2026

Associations of changes in waist-to-height ratio with all-cause mortality among Chinese older adults: a national cohort study

in Nutritional Epidemiology

Juanxia Miao
Xue Wang
Kun Huang
Yiwen Wang
Shuang Zang

Frontiers in Nutrition

doi 10.3389/fnut.2026.1839686

249 views

Original Research

Published on 14 May 2026

Profiling dysregulated circRNA expression in diabetic retinopathy: elucidating putative mediators via a streptozotocin-induced mouse model

in Diabetes: Molecular Mechanisms

Conghui Zhang
Le Feng
Qian Li
Hongping Cui

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1804009

300 views

Original Research

Published on 14 May 2026

Evaluating the diagnostic and prognostic utility of serum DLL1 in acute-on-chronic liver failure patients with bacterial infections

in Hepatobiliary Diseases

Juanjun Huang
Zhi Wang
Wei Zhu
Jian Chen

Frontiers in Medicine

doi 10.3389/fmed.2026.1735014

230 views

Original Research

Published on 14 May 2026

From desert margins to irrigated oases: spatiotemporal dynamics and driving mechanisms of integrated ecological risk in an arid river basin using coupled RSEI-LERI and XGBoost-SHAP frameworks (2001–2025)

in Conservation and Restoration Ecology

Yuanqing Cao
Huihui Wang
Xuan Chen
Zhanfeng Shen
Haoyu Wang
Maolin Li

Frontiers in Ecology and Evolution

doi 10.3389/fevo.2026.1835673

212 views

Original Research

Published on 14 May 2026

The effect of staphylococcal infection on cathelicidin and β-defensin mRNA levels in epithelial cells lining the mammary gland cistern

in Cytokines and Soluble Mediators in Immunity

Emilia Bagnicka
Adrianna Szprynca
Ewa Kościuczuk
Justyna Jarczak
Magdalena Rzewuska
Tomasz Sakowski
Magdalena Zalewska

Frontiers in Immunology

doi 10.3389/fimmu.2026.1804785

249 views

Original Research

Published on 14 May 2026

An ultrasonographic tumor location-based model for predicting central lymph node metastasis in unifocal papillary thyroid microcarcinoma

in Thyroid Endocrinology

Nan Pang
Ranglamu Cai
Wenhui Zhang
Ruoyao Zhang
Qian Sun
Yuyuan Huang
Jie Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1785660

574 views

Case Report

Published on 14 May 2026

Case Report: Long-term survival with erlotinib for lung cancer with secondary leptomeningeal carcinomatosis

in Thoracic Oncology

Diego Neira
Paloma Ruiz
Barbara Nuñez
Gonzalo Navarrete
Rodrigo Vasquez
Luis Villanueva
Olga Barajas

Frontiers in Oncology

doi 10.3389/fonc.2026.1739717

187 views

Review

Published on 14 May 2026

Advances in cryptococcal infections-associated immunopathology and potential therapeutic strategies

in Pharmacology of Infectious Diseases

Nadezhda Sachivkina
Sarmistha Saha
Regina Gurina
Olga Kuznetsova
Natallia Zhabo
Marina Avdonina
Olga Pilshchikova

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1776489

365 views

Original Research

Published on 14 May 2026

SSD-12 somatic symptom disorder scale: replication of validation and introduction of a parent version SSD-12-P

in Psychopathology

Marlene Abel
Stefanie M. Jungmann

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1816120

299 views

Original Research

Published on 14 May 2026

Effect of stress-induced hyperglycaemia on clinical outcome in paitients with acute ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention

in Coronary Artery Disease

Kaidong Zeng
Zhixiong Liao
Yanming Du
Jianping Ding

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1763222

329 views

Articles

First-line immunotherapy for advanced hepatocellular carcinoma: a network meta-analysis of randomized trials with overall and HBV/HCV-stratified efficacy and safety

Adoptive cell therapies in solid tumors: current clinical landscape, challenges, and future directions

Spiritual leadership, flourishing, organizational commitment, and productivity of nurses in healthcare crisis contexts

Reference intervals for plasma IFN-α, TNF-α, IL-12p70, and IFN-γ by flow cytometry in healthy adults from eastern China: a single-center study

Mesenteric perfusion at rest and during feeding in healthy children

A novel glycolipid composite index predicting cardiovascular disease in Chinese adults with abnormal glucose metabolism: a nationwide cohort study

Associations of changes in waist-to-height ratio with all-cause mortality among Chinese older adults: a national cohort study

Profiling dysregulated circRNA expression in diabetic retinopathy: elucidating putative mediators via a streptozotocin-induced mouse model

Evaluating the diagnostic and prognostic utility of serum DLL1 in acute-on-chronic liver failure patients with bacterial infections

From desert margins to irrigated oases: spatiotemporal dynamics and driving mechanisms of integrated ecological risk in an arid river basin using coupled RSEI-LERI and XGBoost-SHAP frameworks (2001–2025)

The effect of staphylococcal infection on cathelicidin and β-defensin mRNA levels in epithelial cells lining the mammary gland cistern

An ultrasonographic tumor location-based model for predicting central lymph node metastasis in unifocal papillary thyroid microcarcinoma

Case Report: Long-term survival with erlotinib for lung cancer with secondary leptomeningeal carcinomatosis

Advances in cryptococcal infections-associated immunopathology and potential therapeutic strategies

SSD-12 somatic symptom disorder scale: replication of validation and introduction of a parent version SSD-12-P

Effect of stress-induced hyperglycaemia on clinical outcome in paitients with acute ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention