Lymphocyte Activation Gene 3 | List of Frontiers open access articles

Original Research

Published on 10 Mar 2021

Lymphocyte Activation Gene 3 (Lag3) Contributes to α-Synucleinopathy in α-Synuclein Transgenic Mice

in Cellular Neuropathology

Hao Gu
Xiuli Yang
Xiaobo Mao
Enquan Xu
Chen Qi
Haibo Wang
Saurav Brahmachari
Bethany York
Manjari Sriparna
Amanda Li

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2021.656426

9,652 views
48 citations

Mini Review

Published on 18 Dec 2024

LAG3 immune inhibitors: a novel strategy for melanoma treatment

in Skin Cancer

Renzheng Wu
Mingtang Zeng
Yuchen Zhang
Jianping He

Frontiers in Oncology

doi 10.3389/fonc.2024.1514578

4,364 views
5 citations

Review

Published on 26 Aug 2024

Advances in understanding the role of immune checkpoint LAG-3 in tumor immunity: a comprehensive review

in Cancer Immunity and Immunotherapy

Yingzhe Luo
Xuebin Cai
Biao Yang
Facheng Lu
Cheng Yi
Guoyu Wu

Frontiers in Oncology

doi 10.3389/fonc.2024.1402837

4,334 views
10 citations

Review

Published on 02 Jul 2020

The Role of Immunomodulatory Receptors in the Pathogenesis of HIV Infection: A Therapeutic Opportunity for HIV Cure?

in Viral Immunology

Hui Chen
Maha Moussa
Marta Catalfamo

Frontiers in Immunology

doi 10.3389/fimmu.2020.01223

11,255 views
31 citations

Original Research

Published on 17 Feb 2021

IL10- and IL35-Secreting MutuDC Lines Act in Cooperation to Inhibit Memory T Cell Activation Through LAG-3 Expression

in Immunological Tolerance and Regulation

Marianna M. Koga
Adrien Engel
Matteo Pigni
Christine Lavanchy
Mathias Stevanin
Vanessa Laversenne
Bernard L. Schneider
Hans Acha-Orbea

Frontiers in Immunology

doi 10.3389/fimmu.2021.607315

6,752 views
16 citations

Review

Published on 14 May 2025

Predictive biomarkers in the era of immunotherapy for gastric cancer: current achievements and future perspectives

in Cancer Immunity and Immunotherapy

Fujing Sun
Xiaozhuo Gao
Wentao Wang
Xiaoyan Zhao
Jingdong Zhang
Yanmei Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1599908

6,058 views
3 citations

Original Research

Published on 22 May 2019

Monitoring Patient Response to Pembrolizumab With Peripheral Blood Exhaustion Marker Profiles

in Dermatology

Moira Graves
Giovana CelliMarchett
Belinda van Zyl
Denise Tang
Ricardo E. Vilain
Andre van der Westhuizen
Nikola A. Bowden

Frontiers in Medicine

doi 10.3389/fmed.2019.00113

9,912 views
22 citations

Original Research

Published on 02 May 2018

CD3ε Expression Defines Functionally Distinct Subsets of Vδ1 T Cells in Patients With Human Immunodeficiency Virus Infection

in T Cell Biology

Pádraic J. Dunne
Christina O. Maher
Michael Freeley
Katie Dunne
Andreea Petrasca
Judy Orikiiriza
Margaret R. Dunne
Derval Reidy
Siobhan O’Dea
Aisling Loy

Frontiers in Immunology

doi 10.3389/fimmu.2018.00940

7,007 views
17 citations

Original Research

Published on 29 Sep 2022

The relationship between soluble lymphocyte activation gene-3 and coronary artery disease

in Coronary Artery Disease

Xinlin Xiong
Zonggang Duan
Haiyan Zhou
Li Niu
Zhenhua Luo
Wei Li

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2022.988582

2,827 views
4 citations

Original Research

Published on 21 Jul 2025

A novel bispecific aptamer targeting LAG3 and HER2 enhances T cell-mediated immunotherapy against HER2-positive cancer cells

in Cancer Immunity and Immunotherapy

Rui Guo
Xiaoyang Chen
Lu Ying
Wenjing Zhang
Zufa Sabeel
Lianhui Zhao
Jian Dong
Yiyang Dong
Zhao Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1557910

4,514 views
2 citations

Original Research

Published on 28 Jul 2023

Prognostic value and immune landscapes of TERT promoter methylation in triple negative breast cancer

in Cancer Immunity and Immunotherapy

Fei Lin
Jiajia Huang
Wancui Zhu
Tongchao Jiang
Jia Guo
Wen Xia
Miao Chen
Ling Guo
Wuguo Deng
Huanxin Lin

Frontiers in Immunology

doi 10.3389/fimmu.2023.1218987

6,420 views
10 citations

Review

Published on 06 Apr 2023

Targeting immune checkpoints in anti-neutrophil cytoplasmic antibodies associated vasculitis: the potential therapeutic targets in the future

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Menglu Pan
Huanhuan Zhao
Ruimin Jin
Patrick S. C. Leung
Zongwen Shuai

Frontiers in Immunology

doi 10.3389/fimmu.2023.1156212

12,114 views
19 citations

Review

Published on 11 Jun 2025

Tiragolumab and TIGIT: pioneering the next era of cancer immunotherapy

in Pharmacology of Anti-Cancer Drugs

Kosar Ghasemi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1568664

7,296 views
14 citations

Original Research

Published on 28 Sep 2023

Blockade of PD-1 and LAG-3 expression on CD8+ T cells promotes the tumoricidal effects of CD8+ T cells

in Cancer Immunity and Immunotherapy

Jiajia Ma
Shufang Yan
Ying Zhao
Huifang Yan
Qian Zhang
Xinxia Li

Frontiers in Immunology

doi 10.3389/fimmu.2023.1265255

7,354 views
28 citations

Original Research

Published on 26 Mar 2025

Exploring the possible mechanism of low-dose naloxone exposure improving the immune microenvironment of gastric cancer tumors

in Cancer Immunity and Immunotherapy

Xiangzhen Min
Yan Ma
Mingyue Lv
Xiaoxi Li
Renjun Lv
Xiaoyong Zhao
Yufang Leng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1524930

5,541 views

Articles

Lymphocyte Activation Gene 3 (Lag3) Contributes to α-Synucleinopathy in α-Synuclein Transgenic Mice

LAG3 immune inhibitors: a novel strategy for melanoma treatment

Advances in understanding the role of immune checkpoint LAG-3 in tumor immunity: a comprehensive review

The Role of Immunomodulatory Receptors in the Pathogenesis of HIV Infection: A Therapeutic Opportunity for HIV Cure?

IL10- and IL35-Secreting MutuDC Lines Act in Cooperation to Inhibit Memory T Cell Activation Through LAG-3 Expression

Predictive biomarkers in the era of immunotherapy for gastric cancer: current achievements and future perspectives

Monitoring Patient Response to Pembrolizumab With Peripheral Blood Exhaustion Marker Profiles

CD3ε Expression Defines Functionally Distinct Subsets of Vδ1 T Cells in Patients With Human Immunodeficiency Virus Infection

The relationship between soluble lymphocyte activation gene-3 and coronary artery disease

A novel bispecific aptamer targeting LAG3 and HER2 enhances T cell-mediated immunotherapy against HER2-positive cancer cells

Prognostic value and immune landscapes of TERT promoter methylation in triple negative breast cancer

Targeting immune checkpoints in anti-neutrophil cytoplasmic antibodies associated vasculitis: the potential therapeutic targets in the future

Tiragolumab and TIGIT: pioneering the next era of cancer immunotherapy

Blockade of PD-1 and LAG-3 expression on CD8+ T cells promotes the tumoricidal effects of CD8+ T cells

Exploring the possible mechanism of low-dose naloxone exposure improving the immune microenvironment of gastric cancer tumors