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3 articles related to "M4 Helix"

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Articles

Original Research

Published on 04 May 2022

Mutations of the nACh Receptor M4 Helix Reveal Different Phenotypes in Different Expression Systems: Could Lipids be Responsible?

in Membrane Physiology and Membrane Biophysics

Susanne M. Mesoy
Matthew Bridgland-Taylor
Sarah C. R. Lummis

Frontiers in Physiology

doi 10.3389/fphys.2022.850782

2,536 views
4 citations

Review

Accepted on 21 Apr 2026

Direct Modulation of Human GABA-A α1β2γ2 Receptors by the Endocannabinoid 2-Arachidonoylglycerol: Implications for Cannabinoid-Related Ligands and Limitations for Anxiolytic Drug Development

in Neuropharmacology

Edgar Mixcoha
Anabel Flores Zamora
Ricardo Hernandez-Miramontes
Jorge Alberto Hernández-Calderón
Susana Martiñon

Frontiers in Neuroscience

291 views

Original Research

Published on 30 Apr 2021

A Single Mutation in the Outer Lipid-Facing Helix of a Pentameric Ligand-Gated Ion Channel Affects Channel Function Through a Radially-Propagating Mechanism

in Biological Modeling and Simulation

Alessandro Crnjar
Susanne M. Mesoy
Sarah C. R. Lummis
Carla Molteni

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.644720

4,136 views
5 citations