Mapk Erk | List of Frontiers open access articles

Original Research

Published on 05 Jan 2026

PELI1 in human cancers: a pan-cancer exploration of its molecular function, clinical significance, and immunomodulatory roles

in Cancer Immunity and Immunotherapy

Yan Xu
Jiale Zhou
Xiaoran Chen
Xiaoqing Dong
Bing Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1682086

984 views

Original Research

Published on 29 Apr 2022

The Natural Product Andrographolide Ameliorates Calcific Aortic Valve Disease by Regulating the Proliferation of Valve Interstitial Cells via the MAPK-ERK Pathway

in Experimental Pharmacology and Drug Discovery

Yuming Huang
Ming Liu
Chungeng Liu
Nianguo Dong
Liang Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2022.871748

6,087 views
14 citations

Original Research

Published on 05 Jan 2022

Discovery of Small Molecule NSC290956 as a Therapeutic Agent for KRas Mutant Non-Small-Cell Lung Cancer

in Pharmacology of Anti-Cancer Drugs

Jiaxin Zhang
Zuojia Liu
Wenjing Zhao
Xunzhe Yin
Xiliang Zheng
Chuanbo Liu
Jin Wang
Erkang Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.797821

5,194 views
5 citations

Original Research

Published on 08 Jun 2021

Reduced PHLPP Expression Leads to EGFR-TKI Resistance in Lung Cancer by Activating PI3K-AKT and MAPK-ERK Dual Signaling

in Cancer Molecular Targets and Therapeutics

Wei Wang
Xinhang Xia
Kuifei Chen
Meng Chen
Yinnan Meng
Dongqing Lv
Haihua Yang

Frontiers in Oncology

doi 10.3389/fonc.2021.665045

6,437 views
17 citations

Original Research

Published on 04 Mar 2021

IL-12p40/IL-23p40 Blockade With Ustekinumab Decreases the Synovial Inflammatory Infiltrate Through Modulation of Multiple Signaling Pathways Including MAPK-ERK and Wnt

in Cytokines and Soluble Mediators in Immunity

Renée H. Fiechter
Henriëtte M. de Jong
Leonieke J. J. van Mens
Inka A. Fluri
Sander W. Tas
Dominique L. P. Baeten
Nataliya G. Yeremenko
Marleen G. H. van de Sande

Frontiers in Immunology

doi 10.3389/fimmu.2021.611656

9,256 views
28 citations

Original Research

Published on 30 Apr 2021

Novel Insight Into the Role of Immune Dysregulation in Amyotrophic Lateral Sclerosis Based on Bioinformatic Analysis

in Neurogenomics

Yongzhi Xie
Ximei Luo
Haiqing He
Min Tang

Frontiers in Neuroscience

doi 10.3389/fnins.2021.657465

8,972 views
16 citations

Articles

PELI1 in human cancers: a pan-cancer exploration of its molecular function, clinical significance, and immunomodulatory roles

The Natural Product Andrographolide Ameliorates Calcific Aortic Valve Disease by Regulating the Proliferation of Valve Interstitial Cells via the MAPK-ERK Pathway

Discovery of Small Molecule NSC290956 as a Therapeutic Agent for KRas Mutant Non-Small-Cell Lung Cancer

Reduced PHLPP Expression Leads to EGFR-TKI Resistance in Lung Cancer by Activating PI3K-AKT and MAPK-ERK Dual Signaling

IL-12p40/IL-23p40 Blockade With Ustekinumab Decreases the Synovial Inflammatory Infiltrate Through Modulation of Multiple Signaling Pathways Including MAPK-ERK and Wnt

Novel Insight Into the Role of Immune Dysregulation in Amyotrophic Lateral Sclerosis Based on Bioinformatic Analysis