Metallodrugs | List of Frontiers open access articles

Systematic Review

Published on 31 Aug 2023

Metallodrugs in the battle against non-small cell lung cancer: unlocking the potential for improved therapeutic outcomes

in Pharmacology of Anti-Cancer Drugs

Xianzhi Xu
Feng Dai
Yiting Mao
Kai Zhang
Ying Qin
Jiwei Zheng

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1242488

4,838 views
15 citations

Review

Published on 07 Apr 2025

The outcast of medicine: metals in medicine--from traditional mineral medicine to metallodrugs

in Ethnopharmacology

Donghan Bai
Michal Nowak
Dajun Lu
Qiaochu Wang
Martin Fitzgerald
Hui Zhang
Remy MacDonald
Ziwen Xu
Lu Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1542560

6,133 views
4 citations

Mini Review

Published on 30 Jan 2026

Ferritin-metallodrugs nanocomposites: light and shadow of drugs loading methods

in Bioinorganic Chemistry

Rosanna Lucignano
Giarita Ferraro

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1740075

307 views

Original Research

Published on 01 Dec 2021

1H -NMR Metabolomics Study of the Effect of Cisplatin and Casiopeina IIgly on MDA-MB-231 Breast Tumor Cells

in Molecular Diagnostics and Therapeutics

Karen Resendiz-Acevedo
Martha E. García-Aguilera
Nuria Esturau-Escofet
Lena Ruiz-Azuara

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.742859

4,062 views
13 citations

Perspective

Published on 28 Jan 2026

Protein metalation by anticancer metal-based drugs revealed through the integration of ESI-MS and XRD measurements. State of the art and open issues

in Bioinorganic Chemistry

Antonello Merlino
Tiziano Marzo
Luigi Messori

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1758486

326 views

Editorial

Published on 15 Dec 2025

Editorial: Metallodrugs in cancer therapy

in Inorganic Chemistry

Suman Adhikari
M. Montazerozohori
Anjoy Majhi
Surajit Pathak

Frontiers in Chemistry

doi 10.3389/fchem.2025.1758341

1,447 views

Review

Published on 23 Jul 2021

Cellular Basis of Organotin(IV) Derivatives as Anticancer Metallodrugs: A Review

in Medicinal and Pharmaceutical Chemistry

Sharifah Nadhira Syed Annuar
Nurul Farahana Kamaludin
Normah Awang
Kok Meng Chan

Frontiers in Chemistry

doi 10.3389/fchem.2021.657599

9,936 views
92 citations

Mini Review

Published on 20 May 2020

Gold(III) Complexes: An Overview on Their Kinetics, Interactions With DNA/BSA, Cytotoxic Activity, and Computational Calculations

in Medicinal and Pharmaceutical Chemistry

Snežana Radisavljević
Biljana Petrović

Frontiers in Chemistry

doi 10.3389/fchem.2020.00379

13,534 views
51 citations

Review

Published on 25 Apr 2024

A review of hydrazide-hydrazone metal complexes’ antitumor potential

in Bioinorganic Chemistry

Nádia Ribeiro
Isabel Correia

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1398873

20,890 views
25 citations

Original Research

Published on 02 Oct 2018

Decavanadate Salts of Cytosine and Metformin: A Combined Experimental-Theoretical Study of Potential Metallodrugs Against Diabetes and Cancer

in Inorganic Chemistry

Eduardo Sánchez-Lara
Samuel Treviño
Brenda L. Sánchez-Gaytán
Enrique Sánchez-Mora
María Eugenia Castro
Francisco J. Meléndez-Bustamante
Miguel A. Méndez-Rojas
Enrique González-Vergara

Frontiers in Chemistry

doi 10.3389/fchem.2018.00402

8,974 views
50 citations

Editorial

Published on 31 May 2024

Editorial: Metallodrugs in cancer therapy: past, present and new strategies

in Medicinal and Pharmaceutical Chemistry

Irena Kostova

Frontiers in Chemistry

doi 10.3389/fchem.2024.1428502

2,042 views
3 citations

Original Research

Published on 26 Jan 2023

Interaction of copper potential metallodrugs with TMPRSS2: A comparative study of docking tools and its implications on COVID-19

in Medicinal and Pharmaceutical Chemistry

Sergio Vazquez-Rodriguez
Diego Ramírez-Contreras
Lisset Noriega
Amalia García-García
Brenda L. Sánchez-Gaytán
Francisco J. Melendez
María Eugenia Castro
Walter Filgueira de Azevedo
Enrique González-Vergara

Frontiers in Chemistry

doi 10.3389/fchem.2023.1128859

4,712 views
32 citations

Original Research

Published on 27 Mar 2023

Synthesis, characterization, and antibacterial activities of a heteroscorpionate derivative platinum complex against methicillin-resistant Staphylococcus aureus

in Clinical and Diagnostic Microbiology and Immunology

Syong H. Nam-Cha
Elena Domínguez-Jurado
Selena L. Tinoco-Valencia
Ramón Pérez-Tanoira
Noelia Morata-Moreno
Rocío Alfaro-Ruiza
Agustín Lara-Sánchez
Jaime Esteban
Rafael Luján
Carlos Alonso-Moreno

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2023.1100947

5,252 views
6 citations

Original Research

Accepted on 02 Mar 2026

Comparative reactivity studies of imine-copper(II) and zinc(II) complexes containing both oxindole-and benzimidazole-scaffolds toward biomolecules and tumor cells

in Structure, Spectroscopy & Imaging

Aline M. L. Zaballa
Ana Paula Araujo De Oliveira
Rodrigo Boni Fazzi
Raphael de Paiva
Carla C. Oliveira
Sayuri Miyamoto
Ana Maria da Costa Ferreira

Frontiers in Chemical Biology

Review

Published on 17 Sep 2021

Recent Advances in Repurposing Disulfiram and Disulfiram Derivatives as Copper-Dependent Anticancer Agents

in Cellular Biochemistry

Vinodh Kannappan
Misha Ali
Benjamin Small
Gowtham Rajendran
Salena Elzhenni
Hamza Taj
Weiguang Wang
Q. Ping Dou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.741316

26,538 views
127 citations

Original Research

Published on 21 Oct 2020

Reactions of Medicinal Gold(III) Compounds With Proteins and Peptides Explored by Electrospray Ionization Mass Spectrometry and Complementary Biophysical Methods

in Medicinal and Pharmaceutical Chemistry

Lara Massai
Carlotta Zoppi
Damiano Cirri
Alessandro Pratesi
Luigi Messori

Frontiers in Chemistry

doi 10.3389/fchem.2020.581648

4,685 views
51 citations

Articles

Metallodrugs in the battle against non-small cell lung cancer: unlocking the potential for improved therapeutic outcomes

The outcast of medicine: metals in medicine--from traditional mineral medicine to metallodrugs

Ferritin-metallodrugs nanocomposites: light and shadow of drugs loading methods

1H -NMR Metabolomics Study of the Effect of Cisplatin and Casiopeina IIgly on MDA-MB-231 Breast Tumor Cells

Protein metalation by anticancer metal-based drugs revealed through the integration of ESI-MS and XRD measurements. State of the art and open issues

Editorial: Metallodrugs in cancer therapy

Cellular Basis of Organotin(IV) Derivatives as Anticancer Metallodrugs: A Review

Gold(III) Complexes: An Overview on Their Kinetics, Interactions With DNA/BSA, Cytotoxic Activity, and Computational Calculations

A review of hydrazide-hydrazone metal complexes’ antitumor potential

Decavanadate Salts of Cytosine and Metformin: A Combined Experimental-Theoretical Study of Potential Metallodrugs Against Diabetes and Cancer

Editorial: Metallodrugs in cancer therapy: past, present and new strategies

Interaction of copper potential metallodrugs with TMPRSS2: A comparative study of docking tools and its implications on COVID-19

Synthesis, characterization, and antibacterial activities of a heteroscorpionate derivative platinum complex against methicillin-resistant Staphylococcus aureus

Comparative reactivity studies of imine-copper(II) and zinc(II) complexes containing both oxindole-and benzimidazole-scaffolds toward biomolecules and tumor cells

Recent Advances in Repurposing Disulfiram and Disulfiram Derivatives as Copper-Dependent Anticancer Agents

Reactions of Medicinal Gold(III) Compounds With Proteins and Peptides Explored by Electrospray Ionization Mass Spectrometry and Complementary Biophysical Methods