Open Problems | List of Frontiers open access articles

Clinical Trial

Published on 03 Mar 2026

Liposomal bupivacaine for popliteal sciatic and saphenous nerve blocks in patients undergoing foot and ankle surgery: a single-center, double-blind, randomized controlled trial

in Intensive Care Medicine and Anesthesiology

Jun Wang
Yan Yang
Fu-Qiang Chen
Kang Wang
Xue-Cheng Meng
Jian Zheng

Frontiers in Medicine

doi 10.3389/fmed.2026.1753354

104 views

Original Research

Published on 03 Mar 2026

Development-led low-rise housing in Dubai: translating resident satisfaction into design and planning insights

in Urban Science

Sabreen Dar Amer
Nour Abdel Hamid
Fayqa Akram
Hussam Safieh
Salwa Beheiry
Serter Atabay
Abdullah Gokhan Yilmaz

Frontiers in Built Environment

doi 10.3389/fbuil.2026.1754687

235 views

Original Research

Published on 03 Mar 2026

Pre-service teachers’ situation-specific skills regarding classroom management in physical education: validation of a video-based test instrument

in Assessment, Testing and Applied Measurement

Eric Jeisy
Clemens Berthold
Matthias Baumgartner

Frontiers in Education

doi 10.3389/feduc.2026.1751591

105 views

Review

Published on 03 Mar 2026

Current understanding and advances regarding the adipose-immune-metabolic axis in disease tolerance during sepsis

in Inflammation

Quanyue Du
Fanghao He
Shanchi Zhang
Xiongyan Lan
Yanqiu Pan
Jiajun Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1755423

142 views

Case Report

Published on 03 Mar 2026

Case Report: Periungual Xeligekimab injection for refractory Acrodermatitis continua of Hallopeau

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Peng Cao
Aijie Yuan
Jingchen Yang
Yuning Zhang
Tao Guo
Chen Li

Frontiers in Immunology

doi 10.3389/fimmu.2026.1753175

Original Research

Published on 03 Mar 2026

Networked evolutionary game analysis of low-carbon technology diffusion

in Social Physics

Xiaoxiao Sun
Jianguo Du
Xiaowen Zhu

Frontiers in Physics

doi 10.3389/fphy.2026.1753750

179 views

Original Research

Published on 03 Mar 2026

Ecodesign-driven material selection in fashion design: a methodological proposal and a mock-up tool

in Sustainable Supply Chain Management

Flavia Papile
Barbara Del Curto

Frontiers in Sustainability

doi 10.3389/frsus.2026.1773542

639 views

Opinion

Published on 03 Mar 2026

Peri-implantitis derived extracellular vesicle as vectors of neuroinflammation

in Cellular Neuropathology

Gestter Willian Lattari Tessarin
Rodrigo Martins dos Santos
Luan Felipe Toro

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2026.1773682

251 views

Original Research

Published on 03 Mar 2026

From clinical phenotypes to genomic signatures: machine learning integration for precision tuberculosis treatment prediction

in RNA Bioinformatics

Liping Li
Huanqing Liu
Qian Lei
Tingting Li

Frontiers in Bioinformatics

doi 10.3389/fbinf.2026.1787360

516 views

Original Research

Published on 03 Mar 2026

Real world experience with [68Ga]PentixaFor PET/CT in Primary Aldosteronism using newly developed harmonized diagnostic criteria

in Adrenal Endocrinology

Linus Hesse
Anna Herden
James MacFarlane
Daniel Gillett
Tina Kienitz
Sophie Howarth
Loreen Richter
Dominik Soll
Dominik Spira
Frederike Butz

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1787233

173 views

Original Research

Published on 03 Mar 2026

Divergent surveillance needs and resource allocation for COVID-19 and influenza: insights from a community-based syndromic surveillance study in Shanghai (2024–2025)

in Infectious Diseases: Epidemiology and Prevention

Xiao Yu
Shiying Yuan
Huanyu Wu
Shenghua Mao
Sheng Lin
Xianjin Jiang
Xiaohuan Gong
Chenyan Jiang
Yaxu Zheng
Jian Chen

Frontiers in Public Health

doi 10.3389/fpubh.2026.1777017

226 views

Original Research

Published on 03 Mar 2026

Targeting neuroinflammation: itaconate and mesaconate as therapeutic strategies against H7N7 influenza-associated CNS damage

in Cytokines and Soluble Mediators in Immunity

Melanie Ohm
Wei He
Dunja Bruder
Karsten Hiller
Martin Korte
Shirin Hosseini

Frontiers in Immunology

doi 10.3389/fimmu.2026.1776302

131 views

Opinion

Published on 03 Mar 2026

Do no harm: managing nausea and vomiting in GLP-1 based obesity therapies

in Obesity

Abdulhameed Alhazmi
Carel W. le Roux

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1788698

418 views

Original Research

Published on 03 Mar 2026

Mining the candidate transcription factors modulating dendrobine biosynthesis under phosphate deficiency in Dendrobium officinale Kimura & Migo

in Plant Metabolism and Chemodiversity

Siqi Gui
Jiening Wu
Yifei Shi
Chao Zhuang
Junjie Zhong
Xiaowei Zou
Hui Du
Wei Zhou

Frontiers in Plant Science

doi 10.3389/fpls.2026.1784768

166 views

Review

Published on 03 Mar 2026

Biophilic design in hospital environments: a rapid review of nature-integrated strategies and patient outcomes

in Environmental Health and Exposome

Yishan Du
Mei Xie
Yuanyuan Zou

Frontiers in Public Health

doi 10.3389/fpubh.2026.1786483

123 views

Opinion

Published on 03 Mar 2026

In the room but not on the byline: trust, fear, and the human role in addiction science in the age of AI

in ELSI in Science and Genetics

Anees Bahji

Frontiers in Sociology

doi 10.3389/fsoc.2026.1786377

250 views

Articles

Liposomal bupivacaine for popliteal sciatic and saphenous nerve blocks in patients undergoing foot and ankle surgery: a single-center, double-blind, randomized controlled trial

Development-led low-rise housing in Dubai: translating resident satisfaction into design and planning insights

Pre-service teachers’ situation-specific skills regarding classroom management in physical education: validation of a video-based test instrument

Current understanding and advances regarding the adipose-immune-metabolic axis in disease tolerance during sepsis

Case Report: Periungual Xeligekimab injection for refractory Acrodermatitis continua of Hallopeau

Networked evolutionary game analysis of low-carbon technology diffusion

Ecodesign-driven material selection in fashion design: a methodological proposal and a mock-up tool

Peri-implantitis derived extracellular vesicle as vectors of neuroinflammation

From clinical phenotypes to genomic signatures: machine learning integration for precision tuberculosis treatment prediction

Real world experience with [68Ga]PentixaFor PET/CT in Primary Aldosteronism using newly developed harmonized diagnostic criteria

Divergent surveillance needs and resource allocation for COVID-19 and influenza: insights from a community-based syndromic surveillance study in Shanghai (2024–2025)

Targeting neuroinflammation: itaconate and mesaconate as therapeutic strategies against H7N7 influenza-associated CNS damage

Do no harm: managing nausea and vomiting in GLP-1 based obesity therapies

Mining the candidate transcription factors modulating dendrobine biosynthesis under phosphate deficiency in Dendrobium officinale Kimura & Migo

Biophilic design in hospital environments: a rapid review of nature-integrated strategies and patient outcomes

In the room but not on the byline: trust, fear, and the human role in addiction science in the age of AI