Optimization Problems | List of Frontiers open access articles

Original Research

Published on 01 May 2026

Lobetyolin reshapes gut microbiota and bile acid metabolism to improve androgen-driven PCOS phenotypes in mice

in Microbial Symbioses

Lijuan Li
Pingping Lin
Siyuan Liu
Yuning Zhang
Siqi Wang
Jingtao Liang
Ruyu Wang
Guofeng Duan
Aixiang Chen

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1810261

454 views

Original Research

Published on 01 May 2026

Mating portfolio and neutral mechanisms are primary causes of genet-ramet frequencies and spatial distributions in smooth cordgrass (Spartina alterniflora) along salt marsh tidal gradients

in Evolutionary, Population, and Conservation Genetics

Jewel Tomasula
Seamus Caslin
Gina M. Wimp
Matthew B. Hamilton

Frontiers in Genetics

doi 10.3389/fgene.2026.1810782

508 views

Systematic Review

Published on 01 May 2026

Research trends and knowledge mapping of transcranial direct current stimulation in depression: a bibliometric study based on web of science, Scopus, and PubMed (2000-2025)

in Neurostimulation

Dongyu Feng
Liuyin Jin
Minsha Mei
HongWei Yuan

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1805441

678 views

Original Research

Published on 01 May 2026

Thinking and focusing together: short-term impact of attentional practice and philosophy for children on socio-emotional and cognitive development

in Mental Health and Wellbeing in Education

Nathalie Martin
Chiara Zanetti
Philippe Gay

Frontiers in Education

doi 10.3389/feduc.2026.1804273

374 views

Original Research

Published on 01 May 2026

Environmental dependence of visible anthocyanin accumulation mediated by the CmMYB6–CmbHLH2 complex

in Plant Bioinformatics

Qiwei Deng
Xiuting Zhu
Shuanglin Liu
Jishu Wang
Zhuo Zhou
Xiaoying Yu
Zhenkun Liao
Lu Xu
Yanlin Li
Lili Xiang

Frontiers in Plant Science

doi 10.3389/fpls.2026.1800973

232 views

Original Research

Published on 01 May 2026

Integrative RNA-seq and iRIP-seq analysis links SNRPA overexpression to transcriptomic and splicing alterations in hepatocellular carcinoma cells

in Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

Qingyao Chang
Yidi Wang
Jun Xu

Frontiers in Oncology

doi 10.3389/fonc.2026.1800728

447 views

Review

Published on 01 May 2026

Off-label and investigational drugs in the treatment of gambling disorder: a critical review

in Neuropharmacology

Leon Bissig
Jochen Mutschler

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1806954

330 views

Original Research

Published on 01 May 2026

A porcine circovirus type 2d-based virus-like particle subunit vaccine effectively protects pigs against homologous challenge

in Virology

Pengfei Chen
Yinghui Sun
Mengya Wang
Chunhua Li
Ye Xia
Huili Liu
Linlin Qi
Fusheng Si
Denian Miao

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1802883

497 views

Original Research

Published on 01 May 2026

Acute effects of different resistance training intensities on creative thinking in university students

in Sport Psychology

Jun Zhou
Yiqing Xie
Yemin Han

Frontiers in Sports and Active Living

doi 10.3389/fspor.2026.1807186

762 views

Original Research

Published on 01 May 2026

Therapeutic vulnerability shaped by the microenvironment: multi-omics and AI biomarkers for precision surgical planning in gastrointestinal tumors

in Cancer Cell Biology

Da Guan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1807136

252 views

Original Research

Published on 01 May 2026

Whole-genome sequencing reveals genomic diversity and population structure of mango germplasm from the Jazan region of Saudi Arabia

in Functional and Applied Plant Genomics

Naser B. Almarri
Salwa M. Mostafa
Nada M Alsofuani
Sara Osman
Sara M. Alomran
Mohanad A. Ibrahim
Ibrahim Alrashidi
Omar A. Al-Haidar
Shakeel Ahmad

Frontiers in Plant Science

doi 10.3389/fpls.2026.1808140

465 views

Case Report

Published on 01 May 2026

Case Report: Different faces of LRBA deficiency in five Moroccan families

in Primary Immunodeficiencies

Mohamed Hbibi
Ahamada Elamine
Ibtihal Benhsaien
Mounia Lakhdar Idrissi
Samira Tizki
Jalila El Bakkouri
Moustapha Hida
Fatima Ailal
Ahmed Aziz Bousfiha

Frontiers in Immunology

doi 10.3389/fimmu.2026.1807421

600 views

Review

Published on 01 May 2026

The function of chemokine-driven glial-neuronal interaction in chronic pain

in Autonomic Neuroscience

Mingyuan Fan
Zhi Liang
Jiayi Shen
Hui Yang
Liping Zhao
Min Li
Jie Zheng

Frontiers in Neuroscience

doi 10.3389/fnins.2026.1830053

412 views

Case Report

Published on 01 May 2026

Case Report: Integrated cardiovascular and respiratory training as a novel therapeutic approach in a case of painful left bundle branch block

in Exercise Physiology

Oscar Crisafulli
Venere Quintiero
Caio V. Spaggiari
Anna Odone
Giuseppe D’Antona

Frontiers in Physiology

doi 10.3389/fphys.2026.1793253

330 views

Policy Brief

Published on 01 May 2026

Problematic mental health-related advice: exploring the role and limitations of EU's digital toolbox on the case of #TherapyTok

in Digital Public Health

Tjaša Petročnik

Frontiers in Public Health

doi 10.3389/fpubh.2026.1793306

367 views

Systematic Review

Published on 01 May 2026

Inclusion and exclusion in gaming communities: a systematic review and future directions to increase inclusivity

in Media Psychology

Yiftach Argaman
Tamar Gur
Ben Heller
Yossi Maaravi

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1796305

801 views

Articles

Lobetyolin reshapes gut microbiota and bile acid metabolism to improve androgen-driven PCOS phenotypes in mice

Mating portfolio and neutral mechanisms are primary causes of genet-ramet frequencies and spatial distributions in smooth cordgrass (Spartina alterniflora) along salt marsh tidal gradients

Research trends and knowledge mapping of transcranial direct current stimulation in depression: a bibliometric study based on web of science, Scopus, and PubMed (2000-2025)

Thinking and focusing together: short-term impact of attentional practice and philosophy for children on socio-emotional and cognitive development

Environmental dependence of visible anthocyanin accumulation mediated by the CmMYB6–CmbHLH2 complex

Integrative RNA-seq and iRIP-seq analysis links SNRPA overexpression to transcriptomic and splicing alterations in hepatocellular carcinoma cells

Off-label and investigational drugs in the treatment of gambling disorder: a critical review

A porcine circovirus type 2d-based virus-like particle subunit vaccine effectively protects pigs against homologous challenge

Acute effects of different resistance training intensities on creative thinking in university students

Therapeutic vulnerability shaped by the microenvironment: multi-omics and AI biomarkers for precision surgical planning in gastrointestinal tumors

Whole-genome sequencing reveals genomic diversity and population structure of mango germplasm from the Jazan region of Saudi Arabia

Case Report: Different faces of LRBA deficiency in five Moroccan families

The function of chemokine-driven glial-neuronal interaction in chronic pain

Case Report: Integrated cardiovascular and respiratory training as a novel therapeutic approach in a case of painful left bundle branch block

Problematic mental health-related advice: exploring the role and limitations of EU's digital toolbox on the case of #TherapyTok

Inclusion and exclusion in gaming communities: a systematic review and future directions to increase inclusivity