Optimization Problems | List of Frontiers open access articles

Case Report

Published on 08 May 2026

Myelin oligodendrocyte glycoprotein antibody-associated disease presenting as encephalitis and concurrent Epstein-Barr virus detection: a case series

in Multiple Sclerosis and Neuroimmunology

Runzhe Chen
Xianli Song
Yupeng Du
Sijia Hou
Minzhi Zhang
Rui Liu
Huihui Xue
Jinming Li
Xiaona Xu
Ting Li

Frontiers in Immunology

doi 10.3389/fimmu.2026.1788238

293 views

Original Research

Published on 08 May 2026

A prospective comparison of the diagnostic performance of a high b-value diffusion-weighted image-guided score versus PI-RADS v2.1 for transition zone prostate cancer

in Genitourinary Oncology

Kexin Li
Tianquan Xu
Xin Yan
Shaonan Mi
Miaomiao Jiang
Lu Chen
Fu Kuang

Frontiers in Oncology

doi 10.3389/fonc.2026.1764833

121 views

Review

Published on 08 May 2026

The central role of EMT in tumor progression: mechanistic drivers, biomarker discovery, and therapeutic horizons

in Pharmacology of Anti-Cancer Drugs

Prasanna Srinivasan Ramalingam
Baby Ilma
Md Sadique Hussain
Vikash Jakhmola
Rabab Fatima
Amita Joshi Rana
Mohit Agrawal
Sumel Ashique
Janaki Ramaiah Mekala
Sivakumar Arumugam

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1820481

233 views

Original Research

Published on 08 May 2026

Identification of a plasma proteomic signature associated with sudden cardiac death risk in the UK biobank

in Cardiovascular Epidemiology and Prevention

Sijia Dai
Minjia Wu
Lei Zheng
Yuyu Chen
Shaoni Huang
Jiangyan Hao
Feiling Liu
Xiaowei He
Guangfeng Long
Yunfeng Zou

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1831086

270 views

Original Research

Published on 08 May 2026

Uterine-Sparing vNOTES vs. laparoscopic lateral suspension for pelvic organ prolapse repair: a prospective comparative study of feasibility and early outcomes

in Obstetrics and Gynecological Surgery

Abdurrahman Sengi
Mehmet Nuri Duran
Mayıs Jinda Pekgül
Nurullah Peker

Frontiers in Surgery

doi 10.3389/fsurg.2026.1797662

553 views

Original Research

Published on 08 May 2026

Exercise evokes retained motor performance without neuroprotection in a mouse model of Parkinson’s disease

in Exercise Physiology

Henry M. Skelton
Nathaniel Hyman
Alejandra M. Fernandez
Emma Acerbo
Madison Scott
Ken Berglund
Claire-Anne Gutekunst
Robert E. Gross

Frontiers in Physiology

doi 10.3389/fphys.2026.1796624

230 views

Original Research

Published on 08 May 2026

Does vertical urban development improve or worsen public health? Evidence from skyscraper concentration across U.S. States

in Urban Science

Yuval Arbel

Frontiers in Built Environment

doi 10.3389/fbuil.2026.1625392

297 views

Original Research

Published on 08 May 2026

The impact of interactive literary narrative gamification on executive function development in preschool children: a longitudinal mixed-methods study based on neuroplasticity theory

in Neuropsychology

Qiyu Chen
Fengzhu Zhao

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1656625

290 views

Original Research

Published on 08 May 2026

Elevated protein levels and mRNA upregulation of Lp-PLA2, IL-6, and TNF-α in cardiovascular disease among a Saudi population

in Atherosclerosis and Vascular Medicine

Ziad H. Al-Oanzi
Fawaz O. Alenazy
Zien A. Alhashash
Raghad A. Alshammari
Fouz M. Alruwaili
Aryaf H. Alruwaili
Aryam S. Alruwaili
Ftoon N. Al-Shammri
Shumukh H. Alfuhaigi
Hala M. Alrwily

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1774428

556 views

Review

Published on 08 May 2026

Mesenchymal stromal/stem cell-derived extracellular vesicles in brain disorders: mechanisms of repair and recovery

in Cellular Neuropathology

Masahito Nakazaki
Karen L. Lankford
Ryo Ukai
Ryosuke Hirota
Shinichi Oka
Masanori Sasaki
Jeffery D. Kocsis
Osamu Honmou

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2026.1819046

282 views

Original Research

Published on 08 May 2026

Anatomical spatial-temporal distribution and multivariate risk of acute injuries in elite rugby: a cohort based on prospective surveillance

in Exercise Physiology

Zhuo Chen
Xue Wang
Xiaodong Mei

Frontiers in Physiology

doi 10.3389/fphys.2026.1793768

122 views

Original Research

Published on 08 May 2026

Critical role of accompanying authorized surrogates among the multifactorial determinants of in-hospital delays in patients with acute stroke

in Stroke

Haoyu Wang
Wei Ni
Yao Chen
Haifang Yu
Yarong He

Frontiers in Neurology

doi 10.3389/fneur.2026.1757307

331 views

Systematic Review

Published on 08 May 2026

Association of IL-6 and IL-17 with thyroid eye disease

in Thyroid Endocrinology

Xin Sun
Yanhua Jiang
Zhili Liu
Lei Zhao

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1798278

192 views

Original Research

Published on 08 May 2026

Low follow-up rate after positive prostate cancer screening in southern China: a community-based cross-sectional survey with a prospective component

in Aging and Public Health

Zi-Qiang Li
Jin-Rong Li
Yue Li
Yue-Fen Liang
Jia-Wen Bi
Wei Li

Frontiers in Public Health

doi 10.3389/fpubh.2026.1844078

181 views

Systematic Review

Published on 08 May 2026

Bibliometric analysis of global research trends in spatially fractionated radiotherapy

in Radiation Oncology

Lingling Meng
Yupeng Di
Lin Ma
Baolin Qu

Frontiers in Oncology

doi 10.3389/fonc.2026.1828039

237 views

Original Research

Published on 08 May 2026

Value management implementation for improving sustainability in construction projects: integrating life cycle cost and weighted evaluation analysis

in Construction Management

Ahmad M. Zamil
Mohammad Alhusban
Abdullah Alharkan

Frontiers in Built Environment

doi 10.3389/fbuil.2026.1780599

290 views

Articles

Myelin oligodendrocyte glycoprotein antibody-associated disease presenting as encephalitis and concurrent Epstein-Barr virus detection: a case series

A prospective comparison of the diagnostic performance of a high b-value diffusion-weighted image-guided score versus PI-RADS v2.1 for transition zone prostate cancer

The central role of EMT in tumor progression: mechanistic drivers, biomarker discovery, and therapeutic horizons

Identification of a plasma proteomic signature associated with sudden cardiac death risk in the UK biobank

Uterine-Sparing vNOTES vs. laparoscopic lateral suspension for pelvic organ prolapse repair: a prospective comparative study of feasibility and early outcomes

Exercise evokes retained motor performance without neuroprotection in a mouse model of Parkinson’s disease

Does vertical urban development improve or worsen public health? Evidence from skyscraper concentration across U.S. States

The impact of interactive literary narrative gamification on executive function development in preschool children: a longitudinal mixed-methods study based on neuroplasticity theory

Elevated protein levels and mRNA upregulation of Lp-PLA2, IL-6, and TNF-α in cardiovascular disease among a Saudi population

Mesenchymal stromal/stem cell-derived extracellular vesicles in brain disorders: mechanisms of repair and recovery

Anatomical spatial-temporal distribution and multivariate risk of acute injuries in elite rugby: a cohort based on prospective surveillance

Critical role of accompanying authorized surrogates among the multifactorial determinants of in-hospital delays in patients with acute stroke

Association of IL-6 and IL-17 with thyroid eye disease

Low follow-up rate after positive prostate cancer screening in southern China: a community-based cross-sectional survey with a prospective component

Bibliometric analysis of global research trends in spatially fractionated radiotherapy

Value management implementation for improving sustainability in construction projects: integrating life cycle cost and weighted evaluation analysis