Optimization Program | List of Frontiers open access articles

Systematic Review

Published on 26 Feb 2026

Clinical efficacy of immunotherapy in combination of locoregional therapies for advanced hepatocellular carcinoma: a systematic review and meta-analysis

in Cancer Immunity and Immunotherapy

Xinyue Chen
Mohan Huang
Ranran Liu
Lawrence Wing Chi Chan

Frontiers in Immunology

doi 10.3389/fimmu.2026.1706375

718 views

Perspective

Published on 26 Feb 2026

Neurorehabilitation needs a qualitative perspective: a case exemplar from stroke recovery and rehabilitation

in Motor Neuroscience

Marika Demers
Carolee J. Winstein

Frontiers in Human Neuroscience

doi 10.3389/fnhum.2026.1707789

175 views

Original Research

Published on 26 Feb 2026

Three-dimensional finite element analysis of the effects of different distal-end aligner designs on maxillary premolar distalization

in Biomechanics

Zhijie Yang
Xiangyu Ma
Yang Liu
Tao Xu
Tianwei Shang
Yue Liu
Yifan Zhang
Cunhui Fan

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1775597

Original Research

Published on 26 Feb 2026

Transcriptome profiling reveals tissue-wide gene expression in chili pepper (Capsicum annuum L.) under infection by Phytophthora capsici

in Functional and Applied Plant Genomics

Dennis Nicuh Lozada
Patricia Cabrales-Arellano
Jerlie Mhay Matres
Jorge Gil C. Angeles
Victor Velazquez-Martinez
Navdeep Kaur
Efren Delgado
Soum Sanogo

Frontiers in Plant Science

doi 10.3389/fpls.2026.1745952

316 views

Systematic Review

Published on 26 Feb 2026

Genomic landscape and subgroup stratification of thymic epithelial tumors: a systematic meta-analysis of next-generation sequencing data

in Thoracic Oncology

Eleonora Pardini
Serena Barachini
Marina Montali
Irene Sofia Burzi
Gisella Sardo Infirri
Daniele Tagliafierro
Iacopo Petrini

Frontiers in Oncology

doi 10.3389/fonc.2026.1781510

Original Research

Published on 26 Feb 2026

Associations of modified triglyceride-glucose indices with risks of dementia subtypes and brain structure: a prospective cohort study

in Dementia and Neurodegenerative Diseases

Hanying Duan
Jiayao Liu
Xiaodong Pan
Tianwen Huang
Xiaochun Chen

Frontiers in Neurology

doi 10.3389/fneur.2026.1750736

276 views

Community Case Study

Published on 26 Feb 2026

Operationalizing ESG in higher education: a pentagonal integral model approach

in Sustainable Organizations

Abror Juraev
Nilufar Omonova
Gaini Mukhanova
Nodira Makhmudova
Aruzhan Abdybaeyva
Ziyodulla Nurov
Rakhmon Amanov
Fotima Khodjaeva
Erkin Farmanov

Frontiers in Sustainability

doi 10.3389/frsus.2026.1788355

160 views

Original Research

Published on 26 Feb 2026

Digital influencers as drivers of purchase intentions and promoters of conscious consumption

in Social Networks

Adriana Oliveira
Helena Costa Oliveira
João Paulo Martins
Mariana Areal

Frontiers in Human Dynamics

doi 10.3389/fhumd.2026.1769412

Original Research

Published on 26 Feb 2026

Integrated bioinformatics and mendelian randomization reveal a six-gene diagnostic signature and key role of CYP26B1 in sarcopenia

in Molecular Diagnostics and Therapeutics

Yaoqi Wu
Xiaoqing Cai
Shiwen Fan
Lina Zhao
Yingying Jiao
Tongkai Chen
Manting Liu
Yafang Song

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1760938

122 views

Review

Published on 26 Feb 2026

Cell-free mitochondrial DNA (cf-mtDNA) in human body fluids: molecular characteristics, release mechanisms, and clinical translation—an updated review

in Molecular Diagnostics and Therapeutics

Yu Liu
Xixiang Ma
Qingmei Guan
Shunchang Zhou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1774015

120 views

Review

Published on 26 Feb 2026

Insights into the potential pathogenesis and therapeutic implications of ferroptosis in brain microvascular endothelial cells during stroke

in Multiple Sclerosis and Neuroimmunology

Wenxiu Qin
Yiran Zhao
Jianqiang Du
Qiaoli Zhang
Gang Wei
Shaokang Wang
Ziru Yu
Junfeng Xu
Jian Yang
Ying Gao

Frontiers in Immunology

doi 10.3389/fimmu.2026.1787418

276 views

Systematic Review

Published on 26 Feb 2026

The digital evolution of surgical planning: a systematic review of immersive and interactive technologies

in Surgical Oncology

Waleed Daifallah Khubzan
Shuruq Awad Alharati
Rimas Warid Aljuaid
Dhay Saleem Algethami
Suhaiyh Sanad Alotibi
Haya Msfeir Alotaibi
Shaden Sultan Aljuaid
Rimas Salem Almalki
Mohammad Eid M. Mahfouz

Frontiers in Surgery

doi 10.3389/fsurg.2026.1764132

169 views

Systematic Review

Published on 26 Feb 2026

Research–evidence gap analysis of hypofractionated radiotherapy for breast cancer: a bibliometric knowledge graph study

in Breast Cancer

Bingyu Liu
Junbao Xu
Jianing Wang
Feng Liu
Hui Xing
Shuai Wang
Xiaohua Zhao
Longgang Wang

Frontiers in Oncology

doi 10.3389/fonc.2026.1746949

Original Research

Published on 26 Feb 2026

Short-term HRV metrics as a method for intraoperative assessment of cardiac parasympathetic response to rapid atrial pacing

in Cardiac Electrophysiology

Przemysław Skoczyński
Bruno Hrymniak
Bartosz Skonieczny
Krystian Josiak
Bartosz Biel
Antoni Wileczek
Katarzyna Czarnecka
Sebastian Stec
Waldemar Banasiak
Dorota Zyśko

Frontiers in Physiology

doi 10.3389/fphys.2026.1753958

218 views

Review

Published on 26 Feb 2026

The brain–bone–gut axis: a microbial bridge underlying multisystem comorbidities

in Gut Endocrinology

Xingli Xu
Qinghan Ma
Peijie You
Jiong Wu

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1755305

Case Report

Published on 26 Feb 2026

A rare pulmonary epithelioid angiosarcoma with ALK rearrangement: a case report and literature review

in Cancer Genetics

Jiuyu Gong
Li Zheng
Fangfang Tian
Peixin Xiao
Dong Yu
Lin Jiang
Pengtao Bao

Frontiers in Oncology

doi 10.3389/fonc.2026.1780353

Articles

Clinical efficacy of immunotherapy in combination of locoregional therapies for advanced hepatocellular carcinoma: a systematic review and meta-analysis

Neurorehabilitation needs a qualitative perspective: a case exemplar from stroke recovery and rehabilitation

Three-dimensional finite element analysis of the effects of different distal-end aligner designs on maxillary premolar distalization

Transcriptome profiling reveals tissue-wide gene expression in chili pepper (Capsicum annuum L.) under infection by Phytophthora capsici

Genomic landscape and subgroup stratification of thymic epithelial tumors: a systematic meta-analysis of next-generation sequencing data

Associations of modified triglyceride-glucose indices with risks of dementia subtypes and brain structure: a prospective cohort study

Operationalizing ESG in higher education: a pentagonal integral model approach

Digital influencers as drivers of purchase intentions and promoters of conscious consumption

Integrated bioinformatics and mendelian randomization reveal a six-gene diagnostic signature and key role of CYP26B1 in sarcopenia

Cell-free mitochondrial DNA (cf-mtDNA) in human body fluids: molecular characteristics, release mechanisms, and clinical translation—an updated review

Insights into the potential pathogenesis and therapeutic implications of ferroptosis in brain microvascular endothelial cells during stroke

The digital evolution of surgical planning: a systematic review of immersive and interactive technologies

Research–evidence gap analysis of hypofractionated radiotherapy for breast cancer: a bibliometric knowledge graph study

Short-term HRV metrics as a method for intraoperative assessment of cardiac parasympathetic response to rapid atrial pacing

The brain–bone–gut axis: a microbial bridge underlying multisystem comorbidities

A rare pulmonary epithelioid angiosarcoma with ALK rearrangement: a case report and literature review