Pim 1 | List of Frontiers open access articles

Original Research

Published on 07 Oct 2024

Molecular insights and inhibitory dynamics of flavonoids in targeting Pim-1 kinase for cancer therapy

in Ethnopharmacology

Hani A. Alhadrami
Ahmed M. Sayed
Hossam M. Hassan
Albaraa H. Alhadrami
Mostafa E. Rateb

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1440958

3,558 views
4 citations

Original Research

Published on 21 Apr 2026

A novel quinine derivative as a PIM-1 kinase inhibitor induces apoptosis via mitochondrial depolarization with selective cytotoxicity in acute lymphoblastic leukemia cells

in Experimental Pharmacology and Drug Discovery

Viviana Donoso-Bustamante
Edison H. Osorio
Gabriela C. Torres
José A. López-Saenz
Renato J. Aguilera
Denisse A. Gutiérrez
Armando Varela-Ramírez
Yeray A. Rodríguez-Núñez
Javier Echeverría

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1799674

490 views

Original Research

Published on 15 Nov 2018

New Pim-1 Kinase Inhibitor From the Co-culture of Two Sponge-Associated Actinomycetes

in Medicinal and Pharmaceutical Chemistry

Seham S. El-Hawary
Ahmed M. Sayed
Rabab Mohammed
Mohammad A. Khanfar
Mostafa E. Rateb
Tarek A. Mohammed
Dina Hajjar
Hossam M. Hassan
Tobias A. M. Gulder
Usama Ramadan Abdelmohsen

Frontiers in Chemistry

doi 10.3389/fchem.2018.00538

10,124 views
46 citations

Original Research

Published on 10 Mar 2023

Combining machine learning and structure-based approaches to develop oncogene PIM kinase inhibitors

in Medicinal and Pharmaceutical Chemistry

Haifa Almukadi
Gada Ali Jadkarim
Arif Mohammed
Majid Almansouri
Nasreen Sultana
Noor Ahmad Shaik
Babajan Banaganapalli

Frontiers in Chemistry

doi 10.3389/fchem.2023.1137444

5,333 views
6 citations

Original Research

Published on 12 Aug 2021

Novel Bis-Thiazole Derivatives: Synthesis and Potential Cytotoxic Activity Through Apoptosis With Molecular Docking Approaches

in Organic Chemistry

Kamal M. Dawood
Mohamed A. Raslan
Ashraf A. Abbas
Belal E. Mohamed
Magda H. Abdellattif
Mohamed S. Nafie
Mohamed K. Hassan

Frontiers in Chemistry

doi 10.3389/fchem.2021.694870

14,722 views
42 citations

Original Research

Published on 26 Mar 2021

Knockdown of LncRNA PANDAR by CRISPR-dCas9 Decreases Proliferation and Increases Apoptosis in Oral Squamous Cell Carcinoma

in Molecular Diagnostics and Therapeutics

Tingting Jia
Fengze Wang
Bo Qiao
Yipeng Ren
Lejun Xing
Haizhong Zhang
Hongbo Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.653787

5,151 views
13 citations

Original Research

Published on 21 Oct 2024

Comprehensive liquid biopsy analysis for monitoring NSCLC patients under second-line osimertinib treatment

in Molecular and Cellular Oncology

Aliki Ntzifa
Theodoros Marras
Galatea Kallergi
Athanasios Kotsakis
Vasilis Georgoulias
Evi Lianidou

Frontiers in Oncology

doi 10.3389/fonc.2024.1435537

5,783 views
7 citations

Articles

Molecular insights and inhibitory dynamics of flavonoids in targeting Pim-1 kinase for cancer therapy

A novel quinine derivative as a PIM-1 kinase inhibitor induces apoptosis via mitochondrial depolarization with selective cytotoxicity in acute lymphoblastic leukemia cells

New Pim-1 Kinase Inhibitor From the Co-culture of Two Sponge-Associated Actinomycetes

Combining machine learning and structure-based approaches to develop oncogene PIM kinase inhibitors

Novel Bis-Thiazole Derivatives: Synthesis and Potential Cytotoxic Activity Through Apoptosis With Molecular Docking Approaches

Knockdown of LncRNA PANDAR by CRISPR-dCas9 Decreases Proliferation and Increases Apoptosis in Oral Squamous Cell Carcinoma

Comprehensive liquid biopsy analysis for monitoring NSCLC patients under second-line osimertinib treatment