Preclinical Stage | List of Frontiers open access articles

Original Research

Published on 02 Oct 2025

Expression levels of interleukin-17 and interferon-γ in peripheral blood and relationship with thyroid function in patients with Hashimoto’s thyroiditis

in Micronutrient Biology

Zhiyong Huang
Jiaming Zhang
Si Chen
Mingfeng Mao
Boyong Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1645736

884 views

Systematic Review

Published on 02 Oct 2025

Influencing factors of digital health technology anxiety in the elderly: a systematic review and meta-analysis

in Psychology of Aging

Ying Han
Jiquan Zhang
Wei Qing
Shouqi Zheng
Lin Xia
Yuxin Li
Lin He

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1645753

2,681 views

Systematic Review

Published on 02 Oct 2025

Global research trends in neurosyphilis: a bibliometric analysis from 2010 to 2024

in Microbial Immunology

Wei Wei
Wei Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1649106

656 views

Original Research

Published on 02 Oct 2025

Historical ecosystem models can serve as a baseline for indicator-based assessment: the North Sea

in Marine Fisheries, Aquaculture and Living Resources

İsmet Saygu
Ruth H. Thurstan
Callum Roberts
Zoe Heard
Ekin Akoglu
Paul R. Halloran

Frontiers in Marine Science

doi 10.3389/fmars.2025.1646031

1,226 views

Original Research

Published on 02 Oct 2025

Projected shifts in the spatio-temporal distribution of larval chub mackerel (Scomber japonicus) under climate change in the western North Pacific

in Global Change and the Future Ocean

Seonggil Go
Sukgeun Jung

Frontiers in Marine Science

doi 10.3389/fmars.2025.1648650

1,301 views

Review

Published on 02 Oct 2025

Targeting RNA-binding proteins with small molecules: perspectives and challenges

in Medicinal and Pharmaceutical Chemistry

Olivier Mpungi Konde
Williams Balela Balela
Tania Bishola Tshitenge

Frontiers in Chemistry

doi 10.3389/fchem.2025.1649692

843 views

Case Report

Published on 02 Oct 2025

Long-term use of cannabis-based medicines in two children with Tourette syndrome: a case report

in Adolescent and Young Adult Psychiatry

Lara-Katharina Woerner
Natalia Szejko
Carolin Fremer
Simon Schmitt
Kirsten R. Müller Vahl

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1647969

610 views

Review

Published on 02 Oct 2025

Emerging macrophage-based therapies for cancer: a review of preclinical and clinical advances

in Cancer Immunity and Immunotherapy

Jan Brancewicz
Paulina Kucharzewska

Frontiers in Immunology

doi 10.3389/fimmu.2025.1679271

402 views

Original Research

Published on 02 Oct 2025

Repairing the medial meniscus posterior root during open-wedge high tibial osteotomy does not significantly affect clinical outcomes

in Orthopedic Surgery

Conglei Dong
Lingce Kong
Yingzhen Niu
Jiangtao Dong

Frontiers in Surgery

doi 10.3389/fsurg.2025.1672154

260 views

Original Research

Published on 02 Oct 2025

Leisure-time physical activity, daily sitting time, and risk of mortality among CVD patients: a prospective cohort study

in Cardiovascular Epidemiology and Prevention

Changnan Xu
Kai Jin
Yike Sun
Mengbiao Cai
Jian Zhu
Yi Yang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1672135

367 views

Original Research

Published on 02 Oct 2025

Clinical efficacy evaluation of TiRobot-assisted minimally invasive treatment for calcaneal fractures based on enhanced recovery after surgery principles

in Orthopedic Surgery

Dai Yonghong
Hong Shi
Wang Shiheng
Zeng Yanhui
Yang Kuangyang
Wang Shaoyun

Frontiers in Surgery

doi 10.3389/fsurg.2025.1673655

243 views

Perspective

Published on 02 Oct 2025

Industrializing the Earth–Moon system: a conceptual study for a space factory at Lagrange point L5

in Space Exploration

Werner Grandl

Frontiers in Space Technologies

doi 10.3389/frspt.2025.1677693

567 views

Original Research

Published on 02 Oct 2025

The impact of modern agricultural technology promotion and adoption on agri-food system resilience

in Food Policy and Economics

Yuting Zhang
Juan Shang
Ziling Yu

Frontiers in Nutrition

doi 10.3389/fnut.2025.1677104

1,007 views

Original Research

Published on 02 Oct 2025

Dose-dependent hemato-biochemical and genotoxic responses of common carp (Cyprinus carpio) to flupyradifurone

in Aquatic Physiology

Önder Yıldırım
Ümit Acar
Rifat Tezel
Yavuz Erden
Gökçen Bilge
Sercan Yapıcı

Frontiers in Physiology

doi 10.3389/fphys.2025.1676992

2,491 views

Original Research

Published on 02 Oct 2025

Combining AI and new genomic techniques to ‘fine-tune’ plants: challenges in risk assessment

in Plant Biotechnology

Matthias Juhas
Bernd Rodekohr
Andreas Bauer-Panskus
Christoph Then

Frontiers in Plant Science

doi 10.3389/fpls.2025.1677066

2,156 views

Original Research

Published on 02 Oct 2025

Bulk and single-cell transcriptome profiling reveals the dynamic immune response in granulomatous amebic encephalitis caused by Balamuthia mandrillaris: a cohort study

in Comparative Immunology

Jingjia Zhang
Xinmiao Jia
Bin Yang
Ying Ge
Wei Jiang
Yang Cong
Huanwen Wu
Huifang Liu
Jingjing Tian
Yingchun Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677014

1,116 views

Articles

Expression levels of interleukin-17 and interferon-γ in peripheral blood and relationship with thyroid function in patients with Hashimoto’s thyroiditis

Influencing factors of digital health technology anxiety in the elderly: a systematic review and meta-analysis

Global research trends in neurosyphilis: a bibliometric analysis from 2010 to 2024

Historical ecosystem models can serve as a baseline for indicator-based assessment: the North Sea

Projected shifts in the spatio-temporal distribution of larval chub mackerel (Scomber japonicus) under climate change in the western North Pacific

Targeting RNA-binding proteins with small molecules: perspectives and challenges

Long-term use of cannabis-based medicines in two children with Tourette syndrome: a case report

Emerging macrophage-based therapies for cancer: a review of preclinical and clinical advances

Repairing the medial meniscus posterior root during open-wedge high tibial osteotomy does not significantly affect clinical outcomes

Leisure-time physical activity, daily sitting time, and risk of mortality among CVD patients: a prospective cohort study

Clinical efficacy evaluation of TiRobot-assisted minimally invasive treatment for calcaneal fractures based on enhanced recovery after surgery principles

Industrializing the Earth–Moon system: a conceptual study for a space factory at Lagrange point L5

The impact of modern agricultural technology promotion and adoption on agri-food system resilience

Dose-dependent hemato-biochemical and genotoxic responses of common carp (Cyprinus carpio) to flupyradifurone

Combining AI and new genomic techniques to ‘fine-tune’ plants: challenges in risk assessment

Bulk and single-cell transcriptome profiling reveals the dynamic immune response in granulomatous amebic encephalitis caused by Balamuthia mandrillaris: a cohort study