Problem Solving Method | List of Frontiers open access articles

Original Research

Published on 12 May 2026

GLP-1 receptor agonists alleviate inflammatory responses and endothelial dysfunction in atherosclerosis by activating the Sema3A/NRP1 pathway

in Lipids in Cardiovascular Disease

Lin Hu
Sanjun Li
Xiaoqin Deng
Zhipeng Zhou
Liu Yang
Bin Li

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1836833

650 views

Original Research

Published on 12 May 2026

Gardenoside restores blood–brain barrier integrity following ischemic stroke via AMPK-dependent ZO-1 preservation

in Pathological Conditions

Rongze Jia

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2026.1768582

296 views

Original Research

Published on 12 May 2026

Psychometric evaluation of the Patient Health Engagement Scale (PHE-s®) in adolescents with chronic diseases: evidence from Türkiye

in Health Psychology

Dilara Usta
Nebahat Bora Güneş
Guendalina Graffigna

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1810006

151 views

Original Research

Published on 12 May 2026

Comprehensive analysis based on tertiary lymphoid structures and tumor budding predicts survival rates in colorectal cancer patients with synchronous liver metastases

in Cancer Immunity and Immunotherapy

Jianzhi Zhang
Hao Zhu
Long Qian
Mengjie Liang
Ji Miao
Haitao Zhu
Xiaofei Shen
Yonghuan Mao
Qiang Li

Frontiers in Immunology

doi 10.3389/fimmu.2026.1776493

256 views

Original Research

Published on 12 May 2026

Preferential enhancement of nitrate utilization in rice by endophytic Burkholderia vietnamiensis RS1

in Plant Symbiotic Interactions

Rina Shinjo
Naoya Ogawa
Kentaro Takahama
Motohiko Kondo

Frontiers in Plant Science

doi 10.3389/fpls.2026.1753845

310 views

Systematic Review

Published on 12 May 2026

E-learning service quality and student satisfaction in public universities: a quantitative hierarchisation of determinants through systematic review

in Higher Education

Jorge Vinueza-Martínez

Frontiers in Education

doi 10.3389/feduc.2026.1818648

251 views

Original Research

Published on 12 May 2026

Characteristics of gut microbiota in pregnant hepatitis b virus carriers and their correlation with liver biochemical indicators

in Intestinal Microbiome

Tao Xie
Hui Wang
Jiawen Yang
Congcong Sun
Dan Li

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2026.1782685

219 views

Review

Published on 12 May 2026

Stress during the first 1,000 days of life in humans, when everything begins

in Cognitive Neuroscience

Tania Vitalis
Catherine Verney

Frontiers in Human Neuroscience

doi 10.3389/fnhum.2026.1781545

248 views

Original Research

Published on 12 May 2026

Digital training needs, cognitive learning ability, and teaching ability of rural teachers: the mediating role of digital literacy and the moderating role of learning engagement

in Educational Psychology

Xinyu Kong

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1821710

517 views

Systematic Review

Published on 12 May 2026

A scoping review of 24-h movement behaviours research in Chinese children and adolescents

in Children and Health

Zhang Feng
Yuanlong Lou

Frontiers in Public Health

doi 10.3389/fpubh.2026.1801708

261 views

Original Research

Published on 12 May 2026

Time-optimal trajectory planning for robotic manipulators based on an improved pufferfish optimization algorithm

in Mechatronics

Xiaofang Guo
Kaiwei Zhuang
Yifang Gao
Yongqiang Xiao
Xinmeng Wu

Frontiers in Mechanical Engineering

doi 10.3389/fmech.2026.1823141

237 views

Original Research

Published on 12 May 2026

Global epidemiological trends, distribution of NTDs and malaria, and disease burden projections for the next 15 years

in Infectious Diseases: Epidemiology and Prevention

Huan Huang
Yang Gao
Huajing Zhu
Yameng Xu
Minli Li
Fanjin Meng
Xinyan Chen
Gengting Du
Weibo Ma
Jiaojiao Qian

Frontiers in Public Health

doi 10.3389/fpubh.2026.1696185

303 views

Original Research

Published on 12 May 2026

Proposed vision for developing an adaptive e-learning environment based on artificial intelligence: a theoretically-grounded framework and its suitability from the perspective of experts

in Digital Education

Sanaa Banat

Frontiers in Education

doi 10.3389/feduc.2026.1727393

212 views

Original Research

Published on 12 May 2026

Bridging CNNs and vision transformers for efficient tea leaf phytopathogen diagnosis: GL-MobFormer

in Sustainable and Intelligent Phytoprotection

Yuntong Yang
Xiaosong Li
Qinzi Li
Yong Sun
Chunjing Yang
Hongxu Chen
Xiaoqing Yuan
Can Hu

Frontiers in Plant Science

doi 10.3389/fpls.2026.1814962

178 views

Systematic Review

Published on 12 May 2026

Induction immunochemotherapy followed by concurrent chemoradiotherapy improves survival in unresectable esophageal cancer: a systematic review, meta-analysis, and network meta-analysis

in Cancer Immunity and Immunotherapy

Xuefei Fan
Xin Liu
Song Mi
Yunxin Yang
Chenggong Li
Jiandong Zhang
Pingping Hu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1767380

113 views

Study Protocol

Published on 12 May 2026

Sintilimab plus fruquintinib with or without radiotherapy for third-line treatment of colorectal cancer with liver metastases: study protocol for a randomized controlled, multicenter phase II trial

in Cancer Immunity and Immunotherapy

Zhenyu Ma
Kunli Zhu
Fang Shi
Rui Feng
Shumei Jiang
Xue Dou
Jing Liu
Zuoxing Niu
Jinbo Yue

Frontiers in Immunology

doi 10.3389/fimmu.2026.1622828

246 views

Articles

GLP-1 receptor agonists alleviate inflammatory responses and endothelial dysfunction in atherosclerosis by activating the Sema3A/NRP1 pathway

Gardenoside restores blood–brain barrier integrity following ischemic stroke via AMPK-dependent ZO-1 preservation

Psychometric evaluation of the Patient Health Engagement Scale (PHE-s®) in adolescents with chronic diseases: evidence from Türkiye

Comprehensive analysis based on tertiary lymphoid structures and tumor budding predicts survival rates in colorectal cancer patients with synchronous liver metastases

Preferential enhancement of nitrate utilization in rice by endophytic Burkholderia vietnamiensis RS1

E-learning service quality and student satisfaction in public universities: a quantitative hierarchisation of determinants through systematic review

Characteristics of gut microbiota in pregnant hepatitis b virus carriers and their correlation with liver biochemical indicators

Stress during the first 1,000 days of life in humans, when everything begins

Digital training needs, cognitive learning ability, and teaching ability of rural teachers: the mediating role of digital literacy and the moderating role of learning engagement

A scoping review of 24-h movement behaviours research in Chinese children and adolescents

Time-optimal trajectory planning for robotic manipulators based on an improved pufferfish optimization algorithm

Global epidemiological trends, distribution of NTDs and malaria, and disease burden projections for the next 15 years

Proposed vision for developing an adaptive e-learning environment based on artificial intelligence: a theoretically-grounded framework and its suitability from the perspective of experts

Bridging CNNs and vision transformers for efficient tea leaf phytopathogen diagnosis: GL-MobFormer

Induction immunochemotherapy followed by concurrent chemoradiotherapy improves survival in unresectable esophageal cancer: a systematic review, meta-analysis, and network meta-analysis

Sintilimab plus fruquintinib with or without radiotherapy for third-line treatment of colorectal cancer with liver metastases: study protocol for a randomized controlled, multicenter phase II trial

Stress during the first 1,000 days of life in humans, when everything begins

Global epidemiological trends, distribution of NTDs and malaria, and disease burden projections for the next 15 years