Problem Solving Method | List of Frontiers open access articles

Original Research

Published on 12 May 2026

Proposed vision for developing an adaptive e-learning environment based on artificial intelligence: a theoretically-grounded framework and its suitability from the perspective of experts

in Digital Education

Sanaa Banat

Frontiers in Education

doi 10.3389/feduc.2026.1727393

212 views

Systematic Review

Published on 12 May 2026

Induction immunochemotherapy followed by concurrent chemoradiotherapy improves survival in unresectable esophageal cancer: a systematic review, meta-analysis, and network meta-analysis

in Cancer Immunity and Immunotherapy

Xuefei Fan
Xin Liu
Song Mi
Yunxin Yang
Chenggong Li
Jiandong Zhang
Pingping Hu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1767380

113 views

Study Protocol

Published on 12 May 2026

Sintilimab plus fruquintinib with or without radiotherapy for third-line treatment of colorectal cancer with liver metastases: study protocol for a randomized controlled, multicenter phase II trial

in Cancer Immunity and Immunotherapy

Zhenyu Ma
Kunli Zhu
Fang Shi
Rui Feng
Shumei Jiang
Xue Dou
Jing Liu
Zuoxing Niu
Jinbo Yue

Frontiers in Immunology

doi 10.3389/fimmu.2026.1622828

246 views

Original Research

Published on 12 May 2026

Development and validation of a measure of early adverse experiences: childhood adversity scale

in Psychopathology

Medaim Yanik
Burcu Uysal
Seyda Eruyar
Ayse Nur Dogan Ceyhan
Erkan Hasan Atalmış

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1701294

472 views

Mini Review

Published on 12 May 2026

Exploring the migration of magic numbers in neutron-rich systems via knockout reactions

in Nuclear Physics

Hongna Liu

Frontiers in Physics

doi 10.3389/fphy.2026.1778872

295 views

Original Research

Published on 12 May 2026

Impact of severe thrombocytopenia on the safety of splenectomy in patients with cirrhosis predominantly caused by Wilson's disease

in Visceral Surgery

Huicong Min
Zhou Zheng
Qingsheng Yu
Yi Shen

Frontiers in Surgery

doi 10.3389/fsurg.2026.1747136

314 views

Original Research

Published on 12 May 2026

Digital climate education for rural resilience: validation and effectiveness of an e-learning module for farmers in flood- and cyclone-prone regions of India

in Climate Risk Management

Sudip Kumar Gorai
Rabindra Nath Padaria
Rajarshi Roy Burman
S. Aiswarya
Shantanu Rakshit
Sujit Sarkar
Bhagirath Das
Md Yeasin
Achal Lama
Sk Wasaful Quader

Frontiers in Climate

doi 10.3389/fclim.2026.1756972

297 views

Original Research

Published on 12 May 2026

Defining reference values for the gut microbiota in a Southern European population

in Intestinal Microbiome

Chiara Pollicardo
Franca Gotta
Paolo Bottino
Daria Vay
Valentina Pizzo
Sara Scaglione
Giulia Pontarollo
Marialuisa Novi
Lara Boatti
Flavio Mignone

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2026.1766733

288 views

Original Research

Published on 12 May 2026

Real-world effectiveness of first-line immunotherapy with or without chemotherapy versus chemotherapy alone in advanced non-small cell lung cancer

in Cancer Immunity and Immunotherapy

Lihua Li
Juan Du
Jing Yang
Limin Chai
Jingxu Nie
Xinfeng Cai
Linxiu He
Junting Jia
Rong Ma
Yimeng Guo

Frontiers in Immunology

doi 10.3389/fimmu.2026.1753591

156 views

Original Research

Published on 12 May 2026

Mechanism of Inonotus hispidus in suppressing renal cell carcinoma proliferation via regulation of the PI3K/AKT/mTOR pathway

in Renal Pharmacology

Yujie Wei
Hui Liu
Anxin Wang
Qi Huang
Ruyi Liu
Hao Yu
Yongxue Song
Ruining Hu
Xiuming Li

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1773406

211 views

Original Research

Published on 12 May 2026

Comparative agreement between tuberculin skin test and QuantiFERON-TB Gold In-Tube across different levels of exposure in a college-based tuberculosis outbreak

in Infectious Diseases: Epidemiology and Prevention

Zheng Sun
Yunliang Wu
Xiaoyan Ding
Qiao Liu
Yan Shao
Haiqing Zhang
Wei Lu
Limei Zhu
Cheng Chen
Leonardo Martinez

Frontiers in Public Health

doi 10.3389/fpubh.2026.1742551

238 views

Brief Research Report

Published on 12 May 2026

A giant solution to the disk mass budget problem of planet formation

in Planetary Science

Sofia Savvidou

Frontiers in Astronomy and Space Sciences

doi 10.3389/fspas.2026.1742823

382 views

Review

Published on 12 May 2026

Research progress of exosomes in renal ischemia-reperfusion injury

in Renal Pharmacology

Supeng Tai
Weibo Wang
Guangyue Luo
Junyue Tao
Chaozhao Liang
Jun Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1763241

227 views

General Commentary

Published on 12 May 2026

Commentary: Concerns regarding the predictive performance of the composite index for mitral regurgitation improvement after TAVI

in Structural Interventional Cardiology

Karim Hnid

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1755552

582 views

Correction

Published on 12 May 2026

Correction: Immunosenescence and metabolic reprogramming in MASLD: an age-dependent immunometabolic vicious cycle and therapeutic opportunities

in Cell Death and Survival

Yuxin Xu
Qiuxiang Li
Xuehua Jiao

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1849677

203 views

Editorial

Published on 12 May 2026

Editorial: Case reports in psychopharmacology, volume IV

in Psychopharmacology

Matej Stuhec
Patricia Di Ciano

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1861985

574 views

Articles

Proposed vision for developing an adaptive e-learning environment based on artificial intelligence: a theoretically-grounded framework and its suitability from the perspective of experts

Induction immunochemotherapy followed by concurrent chemoradiotherapy improves survival in unresectable esophageal cancer: a systematic review, meta-analysis, and network meta-analysis

Sintilimab plus fruquintinib with or without radiotherapy for third-line treatment of colorectal cancer with liver metastases: study protocol for a randomized controlled, multicenter phase II trial

Development and validation of a measure of early adverse experiences: childhood adversity scale

Exploring the migration of magic numbers in neutron-rich systems via knockout reactions

Impact of severe thrombocytopenia on the safety of splenectomy in patients with cirrhosis predominantly caused by Wilson's disease

Digital climate education for rural resilience: validation and effectiveness of an e-learning module for farmers in flood- and cyclone-prone regions of India

Defining reference values for the gut microbiota in a Southern European population

Real-world effectiveness of first-line immunotherapy with or without chemotherapy versus chemotherapy alone in advanced non-small cell lung cancer

Mechanism of Inonotus hispidus in suppressing renal cell carcinoma proliferation via regulation of the PI3K/AKT/mTOR pathway

Comparative agreement between tuberculin skin test and QuantiFERON-TB Gold In-Tube across different levels of exposure in a college-based tuberculosis outbreak

A giant solution to the disk mass budget problem of planet formation

Research progress of exosomes in renal ischemia-reperfusion injury

Commentary: Concerns regarding the predictive performance of the composite index for mitral regurgitation improvement after TAVI

Correction: Immunosenescence and metabolic reprogramming in MASLD: an age-dependent immunometabolic vicious cycle and therapeutic opportunities

Editorial: Case reports in psychopharmacology, volume IV